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Biotechnology Letters

, Volume 17, Issue 6, pp 643–648 | Cite as

α-Amylase production by Bacillus amyloliquefaciens in a membrane recycle bioreactor

  • Caroline Morcel
  • Claus Emborg
  • Søren Madsen
  • K. Biedermann
Article

Abstract

A strain of Bacillus amyloliquefaciens was cultivated in a membrane recycle bioreactor for the production of an extracellular α-amylase. Continuous cultivations of B. amyloliquefaciens in the recycle fermentor led to higher cell mass and volumetric productivities than the ones obtained in batch or chemostat cultivations; the α-amylase activities were lower than in the batch mode but significantly higher than in the chemostat mode. The operation of the membrane recycle bioreactor was sometimes disturbed by high broth viscosity leading to a stronger fouling of the membrane.

Keywords

Viscosity Organic Chemistry Bacillus Cell Mass High Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Chapman & Hall 1995

Authors and Affiliations

  • Caroline Morcel
    • 1
  • Claus Emborg
    • 1
  • Søren Madsen
    • 1
  • K. Biedermann
    • 1
  1. 1.Department of Biotechnology, Building 223The Technical University of DenmarkLyngbyDenmark

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