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Biotechnology Letters

, Volume 15, Issue 5, pp 489–494 | Cite as

The kinetics of end-product inhibition of l-lactate production from xylose and glucose by Lactococcus lactis IO-1

  • Ayaaki Ishizaki
  • Tomoko Ueda
  • Kenji Tanaka
  • Peter F. Stanbury
Article

Summary

The relative contributions of lactate inhibition and the generation of sterile (undividing) cells to the low xylose utilisation rate of Lactococcus lactis IO-1 was investigated. The lactate inhibition constant of xylose grown cells was shown to be 9.3 times more than that of glucose grown cells. However, the sterile cell production rate and LDH inactivation rate of the xylose cultures were at least 10 times less than the glucose cultures. Thus, it is suggested that the slower substrate consumption rate in xylose medium is caused mainly by the large inhibition constant for the end product.

Keywords

Xylose Lactis Inhibition Constant Inactivation Rate Grown Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Chapman & Hall 1993

Authors and Affiliations

  • Ayaaki Ishizaki
    • 1
  • Tomoko Ueda
    • 1
  • Kenji Tanaka
    • 1
  • Peter F. Stanbury
    • 2
  1. 1.Department of Food Science and Technology, Faculty of Agriculture46-09 Kyushu UniversityFukuokaJapan
  2. 2.Division of BiosciencesUniversity of HertfordshireHatfield. Herts.UK

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