In vivo behaviour of three calcium phosphate cements and a magnesium phosphate cement

  • F. C. M. Driessens
  • M. G. Boltong
  • M. I. Zapatero
  • R. M. H. Verbeeck
  • W. Bonfield
  • O. Bérmúdez
  • E. Fernández
  • M. P. Ginebra
  • J. A. Planell
Paper

Three types of calcium phosphate cements and one magnesium phosphate cement were implanted subcutaneously in rats under exclusion of direct cellular contact. Retrieval times were either 1, 2, 4 or 8 weeks. Before and after retrieval the compressive strength, the diametral tensile strength, the quantitative chemical composition, the qualitative phase composition, the FTIR spectrum and the microstructure were determined. The three calcium phosphate cements maintained their strength during implantation. The phase DCPD was completely transformed into a Na- and CO3-containing apatite, the phases DCP and CDHA only partially. It could not be ruled out that OCP is also transformed into a bone-mineral-like apatite to a certain extent. That this latter process occurs much faster during the turn-over of living bone, is probably due to the very small crystal size of the OCP particles in bone.

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Copyright information

© Chapman & Hall 1995

Authors and Affiliations

  • F. C. M. Driessens
    • 1
  • M. G. Boltong
    • 1
  • M. I. Zapatero
    • 2
  • R. M. H. Verbeeck
    • 3
  • W. Bonfield
    • 4
  • O. Bérmúdez
    • 4
  • E. Fernández
    • 1
  • M. P. Ginebra
    • 1
  • J. A. Planell
    • 1
  1. 1.Dept de Ciencia dels Materials i Enginyeria Metal.lúrgicaUniversitat Politècnica de CatalunyaBarcelonaSpain
  2. 2.Centro de Investigación y Desarrollo AplicadoCentro Industrial Santiga(Barcelona)Spain
  3. 3.Laboratory for Analytical ChemistryUniversity of GhentGentBelgium
  4. 4.Interdisciplinary Research Centre in Biomedical MaterialsQueen Mary and Westfield CollegeLondonUK

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