, Volume 5, Issue 3, pp 187–196

Time-to-event analyses of ecotoxicity data

  • Michael C. Newman
  • John T. McCloskey

DOI: 10.1007/BF00116339

Cite this article as:
Newman, M.C. & McCloskey, J.T. Ecotoxicology (1996) 5: 187. doi:10.1007/BF00116339

Intensity and duration of exposure dictate the effect of a toxicant. Consequently, any assessment of ecological risk that does not include a sound understanding of both concentration and duration effects is compromised. This being the case, it is surprising that the predominant approach in ecotoxicology (concentration-effect modeling) inefficiently includes exposure duration. Ecological risk assessment can be enhanced with time-to-event models that can easily include concentration, exposure duration, and other important covariates. Time-to-event methods are described and linkage made to relevant ecological techniques, i.e. life table analyses and genetic selection models.


statistics survival time toxicity ecological risk assessment 

Copyright information

© Chapman & Hall 1996

Authors and Affiliations

  • Michael C. Newman
    • 1
  • John T. McCloskey
    • 1
  1. 1.Savannah River Ecology LaboratoryUniversity of GeorgiaAikenUSA
  2. 2.Savannah River Ecology LaboratoryUniversity of GeorgiaAikenUSA

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