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Cancer Causes & Control

, Volume 4, Issue 5, pp 449–454 | Cite as

Occupational risk factors for lung cancer among nonsmoking women: a case-control study in Missouri (United States)

  • Ross C. Brownson
  • Michael C. R. Alavanja
  • Jian C. Chang
Research Paper

Occupationally related risk of lung cancer among women and among nonsmokers has not been widely studied. A recently conducted population-based, case-control study in Missouri (United States) provided the opportunity to evaluate risk of lung cancer associated with several occupational factors. Incident cases (n=429) were identified through the Missouri Cancer Registry for the period 1986 through 1991, and included 294 lifetime nonsmokers and 135 ex-smokers who had stopped at least 15 years prior to diagnosis or had smoked for less than one pack-year. Controls (n=1,021) were selected through driver's license and Medicare files. Risk was elevated among women exposed to asbestos (ever: odds ratio [OR]=3.5, 95 percent confidence interval [CI]=1.2–10.0; >9 yrs: OR=4.6, CI=1.1–19.2) and pesticides (ever: OR=2.4, CI=1.1–5.6; >17.5 yrs: OR=2.4, CI=0.8–7.0). Risk also was elevated among dry cleaning workers (ever: OR=1.8, CI=1.1–3.0; >1.125 yrs: OR=2.9, CI=1.5–5.4). Occupational risks for lung cancer among women merit further study.

Key words

Asbestos case-control study lung neoplasms occupational diseases smoking United States women 

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Copyright information

© Rapid Communications of Oxford Ltd 1993

Authors and Affiliations

  • Ross C. Brownson
  • Michael C. R. Alavanja
  • Jian C. Chang

There are no affiliations available

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