Structure and function of the receptor-like protein kinases of higher plants
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Cell surface receptors located in the plasma membrane have a prominent role in the initiation of cellular signalling. Recent evidence strongly suggests that plant cells carry cell surface receptors with intrinsic protein kinase activity. The plant receptor-like protein kinases (RLKs) are structurally related to the polypeptide growth factor receptors of animals which consist of a large extracytoplasmic domain, a single membrane spanning segment and a cytoplasmic domain of the protein kinase gene family. Most of the animal growth factor receptor protein kinases are tyrosine kinases; however, the plant RLKs all appear to be serine/threonine protein kinases. Based on structural similarities in their extracellular domains the RLKs fall into three categories: the S-domain class, related to the self-incompatibility locus glycoproteins of Brassica; the leucine-rich repeat class, containing a tandemly repeated motif that has been found in numerous proteins from a variety of eukaryotes; and a third class that has epidermal growth factor-like repeats. Distinct members of these putative receptors have been found in both monocytyledonous plants such as maize and in members of the dicotyledonous Brassicaceae. The diversity among plant RLKs, reflected in their structural and functional properties, has opened up a broad new area of investigation into cellular signalling in plants with far-reaching implications for the mechanisms by which plant cells perceive and respond to extracellular signals.
Key wordsProtein kinase protein phosphorylation receptor self-incompatibility signal transduction
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- 1.Ahn NG, Seger R, Krebs EG: The mitogen-activated protein kinase activator. Curr Biol 4: 992–999 (1992).Google Scholar
- 3.Benson D, Lipman DJ, Ostell J: GenBank. Nucl Acid Res 21: 2963–2965 (1993).Google Scholar
- 20.Kohorn BD, Fujiki M: A family of proteins containing a serine/threonine kinase and/or an EGF repeat hasmembers in the plasma membrane and chloroplast. Fifth International Conference on Arabidopsis Research (1993).Google Scholar
- 26.Mizoguchi T, Gotoh Y, Nishida E, Yamaguchi-Shinozaki K, Hayashida N, Iwasaki T, Kamada H, Shinozaki K: Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. Plant J 5: 111–122 (1994).CrossRefPubMedGoogle Scholar
- 29.Nasrallah JB, Rundle SJ, Nasrallah ME: Genetic evidence for the requirement of the Brassica S-locus receptor kinase gene in the self-incompatibility response. Plant J 5: 373–384 (1994).Google Scholar
- 32.Pearce G, Strydom D, Johnson S, Ryan CA: A polypeptide from tomato leaves induces wound-inducible proteinase inhibitor proteins. Science 253: 895–898 (1991).Google Scholar
- 38.Smith RD, Walker JC: Isolation and expression of a maize type 1 protein phosphatase. Plant Physiol 97: 677–683 (1991).Google Scholar
- 43.Tobias CM, Howlett B, Nasrallah JB: An Arabidopsis thaliana gene with sequence similarity to the S-Locus receptor kinase of Brassica oleracea. Plant Physiol 99: 284–290 (1992).Google Scholar