Summary
The inclusion of vitamin C in the drinking water of BALB/c mice was without effect on the humoral antibody response to sheep red blood cells and bacterial lipopolysaccharide. However, there was a significantly increased cell-mediated immune response as determined by increased T-lymphocyte responses to concanavalin A. This might suggest a mechanism, along with interferon enhancement, for the possible protection by vitamin C against some viral infections.
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Siegel, B.V., Morton, J.I. Vitamin C and the immune response. Experientia 33, 393–395 (1977). https://doi.org/10.1007/BF02002847
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DOI: https://doi.org/10.1007/BF02002847