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The fine structure of blood vessels in chromophobe adenoma

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Summary

The fine structure of the small blood vessels in chromophobe adenoma was compared to normal pituitary. The most striking difference was the relative paucity of endothelial fenestrae in the tumor accompanied by a widened perivascular space. The origin of these changes and their possible functional significance are discussed.

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References

  • Bennett, H. S., Luft, J. H., Hampton, J. C.: Morphological classification of vertebrate blood capillaries. Amer. J. Physiol.196, 381–390 (1959).

    Google Scholar 

  • Bergland, R. M., Torack, R. M.: An ultrastructural study of follicular cells in the human anterior pituitary. Amer. J. Path.57, 273–297 (1969).

    Google Scholar 

  • Cardell, R. R., Knighton, R. S.: The cytology of a human pituitary tumor: An electron microscopic study. Trans. Amer. micr. Soc.85, 58–78 (1966).

    Google Scholar 

  • Farquhar, M. G.: Fine structure and function in capillaries of the anterior pituitary gland. Angiology12, 270–292 (1961).

    Google Scholar 

  • Fukumitsu, T.: Electron microscopic study of the human pituitary adenomas. Arch. jap. Chir.33, 329–349 (1964).

    Google Scholar 

  • Gusek, W.: Vergleichende licht- und elektronenmikroskopische Untersuchungen menschlicher Hypophysenadenome bei Akromegalie. Endokrinologie42, 257–283 (1962).

    Google Scholar 

  • Hirano, A., Zimmerman, H. M., Levine, S.: The fine structure of cerebral fluid accumulation. III. Extracellular spread of cryptococcal polysaccharides in the acute stage. Amer. J. Path.45, 1–19 (1964).

    Google Scholar 

  • ———: The fine structure of cerebral fluid accumulation. IX. Edema following silver nitrate implantation. Amer. J. Path.47, 537–548 (1965).

    Google Scholar 

  • Luse, S.: Ultrastructure characteristics of normal and neoplastic cells. Progr. exp. Tumor Res. (Basel)2, 1–35 (1961).

    Google Scholar 

  • Matsuda, H., Sugiura, S.: Ultrastructure of “tubular body” in the endothelial cells of the ocular blood vessels. Invest. Ophthal.9, 919–925 (1970).

    Google Scholar 

  • Oliva, H., Navarro, V., Obrador, S.: Microscópico electrónica de los adenomas cromófobos de la hipófisis. Acta neurochir. (Wien)14, 141–153 (1966).

    Google Scholar 

  • Poon, T. P., Hirano, A., Zimmerman, H. M.: Electron microscopic atlas of brain tumors. New York: Grune & Stratton 1971.

    Google Scholar 

  • Porter, K. R., Bonneville, M. A.: Fine structure of cells and tissues. Philadelphia: Lea & Feibiger 1968.

    Google Scholar 

  • Rinehart, J. F., Farquhar, M. G.: The fine vascular organization of the anterior pituitary gland. Anat. Rec.121, 207–239 (1955).

    Google Scholar 

  • Salazar, H., MacAulay, M. A., Charles, D., Pardo, M.: The human hypophysis in anancephaly. I. Ultrastructure of the pars distalis. Arch. Path.87, 201–211 (1969).

    Google Scholar 

  • Schelin U.: Chromophobe and acidophil adenomas of the human pituitary gland. A light and electron microscopic study. Acta path. microbiol. scand. Suppl.158, 5–80 (1962).

    Google Scholar 

  • Wechsler, W., Hossmann, K. A.: Elektronenmikroskopische Untersuchungen chromophober Hypophysen-Adenoma des Menschen. Zbl. Neurochir.26, 105–122 (1965).

    Google Scholar 

  • Weibel, E. R., Palade, G. E.: New cytoplasmic components in arterial endothelia. J. Cell Biol.23, 101–112 (1964).

    Google Scholar 

  • Zambrano, D., Amezua, L., Dickmann, G., Franke, E.: Ultrastructure of human pituitary adenoma. Acta neurochir. (Wien)18, 78–94 (1968).

    Google Scholar 

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Hirano, A., Tomiyasu, U. & Zimmerman, H.M. The fine structure of blood vessels in chromophobe adenoma. Acta Neuropathol 22, 200–207 (1972). https://doi.org/10.1007/BF00684523

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  • DOI: https://doi.org/10.1007/BF00684523

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