Abstract
The objective of this study was to investigate the feasibility of potential fiducial markers consisting of various materials in a Vero real-time tumor-tracking (RTTT) system. In order to determine the applicability of fiducial markers for the Vero RTTT system, we tested various markers consisting of 8 kinds of material (titanium, stainless steel, high-carbon steel, pure steel, copper, silver, tantalum, and gold) with various diameters ranging from 0.3 mm to 1.6 mm and a length of 5 mm. Additionally, a commercial gold coil marker (Visicoil™, IBA dosimetry, Schwarzenbruck, Germany) of diameter 0.5 mm and length 1 cm was included for evaluation. The radiologic visibility on kV fluoroscopy/kV CT scan images of the fiducial markers was evaluated. The detectability on the RTTT system was tested using a two-dimensional moving phantom (Brainlab AG, Feldkirchen, Germany), producing sinusoidal motion. The target center’s accuracy was evaluated by calculating the deviation of the position of a metal sphere from the center on the dose profile. Dose profiles were measured using Gafchromic EBT2 films (International Specialty Products, NJ, USA). All markers were visible on kV fluoroscopy/kV CT while markers with atomic number ≥ 25.7 were detectable on the Vero RTTT system. All the detected markers showed excellent geometric accuracy.
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References
T. J. Scarbrough et al., Int. J. Radiat. Oncol. Biol. Phys. 65, 378 (2006).
M. Imura et al., Int. J. Radiat. Oncol. Biol. Phys. 63, 1442 (2005).
D. F. Abawi et al., Accuracy in optical tracking with fiducial markers: An accuracy function for ARToolKit. in Proceedings of the 3rd IEEE/ACM International Symposium on Mixed and Augmented Reality (Arlington, VA, USA, 2004).
K. M. Langen et al., Int. J. Radiat. Oncol. Biol. Phys. 71, 1084 (2008).
R. I. Whyte et al., Annals Thoracic Surg. 75, 1097 (2003).
E. Sotiropoulou et al., Cardiovas. Intervent. Rad. 33, 586 (2010).
J. Loh et al., Rad. Oncol. 10, 38 (2015).
R. Kinoshita et al., Int. J. Radiat, Oncol. Biol. Phys. 70, 931 (2008).
T. Depuydt et al., Radiother. Oncol. 98, 365 (2011).
K. Poels et al., Radiother. Oncol. 112, 352 (2014).
T. Depuydt et al., Radiother. Oncol. 106, 236 (2013).
N. Mukumoto et al., Radiother. Oncol. 111, 301 (2014).
M. L. Taylor et al., Med. Phys. 39, 1769 (2012).
F. M. Kahn and J. P. Gibbons, The Physics of Radiation Therapy (5th Edition, Wolters Kluwer, Lippincott Williams & Wilkins, Philadelphia, 2014), p. 63.
D. Habermehl et al., J. Radiat. Res. 54 Suppl 1, i61 (2013).
J. Carl et al., Acta. Oncol. 47, 1358 (2008).
S. Song et al., Radiother. Oncol. 103, 270 (2012).
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Park, SH., Kim, JC. & Kim, S.J. Alternative fiducial markers for Vero real-time tumor tracking radiotherapy: A phantom study. Journal of the Korean Physical Society 69, 1700–1704 (2016). https://doi.org/10.3938/jkps.69.1700
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DOI: https://doi.org/10.3938/jkps.69.1700
Keywords
- Real-time tumor tracking
- Vero
- Fiducial marker
- Respiratory motion
- Four-dimensional image-guided radiotherapy