Abstract
The information optics techniques, such as polarimetry and spectropolarimetry, are applied for identifying the changes of optical-geometrical structure in various biological tissues with solid tumours. It is shown that a linear dichroism appears in biological tissues (human esophagus, muscle tissue of rats, human prostate tissue, and cervical smear) with cancer diseases whose magnitude depends on the type of tissue and on the time of cancer process development.
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Selected papers on tissue optics: applications in medical diagnostics and therapy, Tuchin, V.V., Ed., Bellingham, SPIE, vol. MS102, 1994.
Tuchin, V.V., Utz, S.R., and Yaroslavsky, I.V., Tissue optics, light distribution, and spectroscopy, Opt. Eng., 1994, vol. 33, pp. 3178–3188.
Alfano, R.R. and Fujimoto, J.G., Eds., Advances in optical imaging and photon migration, Topics in Optics and Photonics Series, Optical Society of America, Washington, D.C., 1996.
Demos, S.G. and Alfano, R.R., Optical Polarization Imaging, Appl. Opt., 1997, vol. 36, pp. 150–155.
Wang, W.B., Ali, J.H., Vitenson, J.H., Lombardo, J.M., and Alfano, R.R., Spectral polarization imaging of human prostate tissues, Proc. SPIE, 2000, vol. 3917, p. 75.
Handbook of Coherent-Domain Optical Methods. Biomedical Diagnostics, Environmental and Material Science, Tuchin, V., ed., Kluwer Academic Publishers, 2004.
Angelsky, O.V., Ushenko, A.G., Burkovets, D.N., and Ushenko, Yu.A., Polarization visualization and selection of biotissue image two-layer scattering medium, Journal of biomedical optics, 2005, vol. 10, no. 1, p. 14010.
Angelsky, O.V., Ushenko, A.G., Archelyuk, A.D., Ermolenko, S.B., and Burkovets, D.N., Structure of matrices for the transformation of laser radiation by biofractals, Quantum Electronics, 1999, vol. 29, no. 12, pp. 1074–1077.
Angelsky, O.V., Polyanskii, P.V., and Felde, C.V., The emerging field of correlation optics, Optics and Photonics News, 2012, vol. 23, no. 4, pp. 25–29.
Bekshaev, A.Y., Angelsky, O.V., Hanson, S.G., and Zenkova, C.Y., Scattering of inhomogeneous circularly polarized optical field and mechanical manifestation of the internal energy flows, Phys. Rev. A, 2012, vol. 86, p. 023847.
Angelsky, O.V., Bekshaev, A.Ya., Maksimyak, P.P., Maksimyak, A.P., Hanson, S.G., and Zenkova, C.Yu., Self-diffraction of continuous laser radiation in a disperse medium with absorbing particles, Optics Express, 2013, vol. 21,issue 7, pp. 8922–8938.
Bartel, S. and Hielscher, A.H., Monte Carlo simulation of the diffuse backscattering Mueller matrix for highly scattering media, Appl. Opt., vol. 39, 2000, pp. 1580–1588.
Wang, X. and Wang, L.V., Propagation of polarized light in birefringent turbid media: A Monte Carlo study, J. Biomed. Opt., 2002, vol. 7, pp. 279–290.
Wang, X., Wang, L.V., Sun, C.-W., and Yang, C.-C., Polarized light propagation through scattering media: time-resolved Monte Carlo simulation and experiments, J. Biomed. Opt., 2003, vol. 8, pp. 608–617.
Heppner, G.H., Tumor heterogeneity, Cancer Res., 1984, vol. 44, pp. 2259–2265.
Martin, D.S., Balis, M.E., Fisher, B., Frei, E., Freireich, E.J., Heppner, G.H., and Holland, J.F., “Role of murine tumor models in cancer treatment research,” Cancer Res., 1986, vol. 46, pp. 2189–2192.
Angelsky, O.V., Ushenko, A.G., Yermolenko, S.B., et al., Polarization-based visualization of multifractal structures for the diagnostics of pathological changes in biological tissues, Optics and Spectroscopy, 2000, vol. 89, pp. 799–804.
Gruia, M.I., Olinescu, R., Marinescu, M., and Gruia, I., Evaluation of antioxidants role in diminution of lipid peroxidation at tumor bearer mice, Rom. J. Comp. Oncol., 2001, vol. 4, pp. 268–273.
Angelsky, O.V., Yermolenko, S.B., Prydij, O.G., Ushenko, A.G., and Ushenko, Ye.G., Polarization-interference structure of speckle fields of the rough skin surface, J. Holography Speckle, 2006, vol. 3, pp. 27–34.
Angelsky, O.V., Yermolenko, S.B., Zenkova, C.Yu., and Angelskaya, A.O., Polarization manifestations of correlation (intrinsic coherence) of optical fields, Appl. Opt., 2008, vol. 47, pp. 5492–5499.
Angelsky, O.V., Demianovsky, G.V., Ushenko, A.G., Burkovets, D.N., Ushenko, Y.A., Wavelet analysis of two-dimensional birefringence images of architectonics in biotissues for diagnosing pathological changes, Journal of Biomedical Optics, 2004, vol. 9, no. 4, pp. 679–690.
Yermolenko, S.B., Ivashko, P.V., Prydij, O.G., and Gruia, I., Statistical analysis of polarized images of biotissues for diagnose of their pathological changes, Optoelectronics and advanced materials-rapid comunications, 2010, vol. 4, no. 4, pp. 527–530.
Gruia, I., Yermolenko, S.B., Gruia, M., Ivashko, P.V., and Stefanescu, T., Spectral and biochemical methods for identification of cellular and tissues malignant changes, Optoelectronics and Advanced Materials-Rapid Communication, 2010, vol. 4, no. 4, pp. 523–526.
Angelsky, O.V., Hanson, S.G., Maksimyak, A.P., and Maksimyak, P.P., Interference diagnostics of surfaces, Optical Memory and Neural Networks (Information Optics), 2007, vol. 16, pp. 269–280.
Zenkova, C.Yu., Yermolenko, S.B., Angelskaya, A.O., and Soltys, I.V., The polarization peculiarities of the correlation (intrinsic coherence) of optical fields, Optical Memory and Neural Networks (Information Optics), 2011, vol. 20, no. 4, pp. 247–254.
Zenkova, C.Yu., Gorsky, M.P., Soltys, I.V., and Angelsky, P.O., The Investigation of the peculiarities of the motion of testing nanoobjects in the inhomogeneously polarized optical field, Optical Memory and Neural Networks (Information Optics), 2012, vol. 21, no. 1, pp. 34–44.
Angelskaya, A.O., Gruia, I., Yermolenko, S.B., Gruia, M., Ivashko, P.V., and Gruia, M.I., Manifestations of linear dichroism changes in cancer biotissues, Romanian Reports in Physics, 2013, vol. 65, no. 3, pp. 1052–1062.
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Yermolenko, S.B., Peresunko, O.P., Gruia, I. et al. Information optics approach in diagnostics of malignant changes of biological tissues. Opt. Mem. Neural Networks 23, 191–199 (2014). https://doi.org/10.3103/S1060992X14030126
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DOI: https://doi.org/10.3103/S1060992X14030126