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4-amino-2-phenylindole-based compounds with potential antibacterial activity

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Moscow University Chemistry Bulletin Aims and scope

Abstract

Primary condensation of 4-amino-2-phenylindole with ethyl acetoacetate and 4,4,4-trifluoroacetoacetate resulted in corresponding amides, which under acidic conditions were converted to pyrrolo[2,3-h]quinolones. Antibacterial activity of the amide obtained from aminoindole and ethyl 4,4,4-trifluoroacetylacetate was detected.

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Authors and Affiliations

  1. Evsev’ev Mordovia State Pedagogical Institute, Saransk, 430007, Russia

    E. A. Alyamkina & S. A. Yamashkin

  2. Ogarev Mordovia State University, Saransk, 430005, Russia

    I. S. Stepanenko

  3. Department of Chemistry, Moscow State University, Moscow, 119991, Russia

    M. A. Yurovskaya

Authors
  1. E. A. Alyamkina
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  2. I. S. Stepanenko
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  3. S. A. Yamashkin
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  4. M. A. Yurovskaya
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Corresponding author

Correspondence to M. A. Yurovskaya.

Additional information

Original Russian Text © E.A. Alyamkina, I.S. Stepanenko, S.A. Yamashkin, M.A. Yurovskaya, 2016, published in Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya, 2016, No. 6, pp. 410–417.

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Alyamkina, E.A., Stepanenko, I.S., Yamashkin, S.A. et al. 4-amino-2-phenylindole-based compounds with potential antibacterial activity. Moscow Univ. Chem. Bull. 72, 24–28 (2017). https://doi.org/10.3103/S0027131417010023

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  • DOI: https://doi.org/10.3103/S0027131417010023

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