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Fast Determination of Toxic Arsenic Species in Food Samples Using Narrow-bore High-Performance Liquid-Chromatography Inductively Coupled Plasma Mass Spectrometry

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Abstract

A new method for the speciation analysis of arsenic in food using narrow-bore high-performance liquid-chromatography inductively coupled plasma mass spectrometry (HPLC-ICP-MS) has been developed. Fast separation of arsenite, arsenate, monomethylarsonic acid and dimethylarsinic acid was carried out in 7 min using an anion-exchange narrow-bore Nucleosil 100 SB column and 12 mM ammonium dihydrogen phosphate of pH 5.2 as the mobile phase, at a flow rate of 0.3 mL min–1. A PFA-ST micronebulizer jointed to a cyclonic spray chamber was used for HPLC-ICP-MS coupling. Compared with standard-bore HPLC-ICP-MS, the new method has provided higher sensitivity, reduced mobile-phase consumption, a lower matrix plasma load and a shorter analysis time. The achieved instrumental limits of detection were in the 0.3–0.4 ng As mL–1 range, and the precision was better than 3%. The arsenic compounds were efficiently (>80%) extracted from various food samples using a 1:5 methanol/water solution, with additional ultrasonic treatment for rice products. The applicability of this method was demonstrated by the analysis of several samples, such as seafood (fish, mussels, shrimps, edible algae) and rice-based products (Jasmine and Arborio rice, spaghetti, flour, crackers), including three certified reference materials.

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Acknowledgments

This research was supported by the Urakami Foundation for Food and Food Culture Promotion.

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Authors and Affiliations

  1. Department of Chemistry and Industrial Chemistry, University of Genoa, Via Dodecaneso 31, 16146, Italy

    Amanda Terol, Francisco Ardini & Marco Grotti

  2. Department of Trace Element Analysis by Spectroscopy Method, Adam Mickiewicz University in Poznań, 89b Umultowska Street, 61-614, Poland

    Monika Marcinkowska

Authors
  1. Amanda Terol
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  2. Monika Marcinkowska
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  3. Francisco Ardini
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  4. Marco Grotti
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Correspondence to Marco Grotti.

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Terol, A., Marcinkowska, M., Ardini, F. et al. Fast Determination of Toxic Arsenic Species in Food Samples Using Narrow-bore High-Performance Liquid-Chromatography Inductively Coupled Plasma Mass Spectrometry. ANAL. SCI. 32, 911–915 (2016). https://doi.org/10.2116/analsci.32.911

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  • DOI: https://doi.org/10.2116/analsci.32.911

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