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Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Bioactive Lignan

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Abstract

Multiphoton ionization time-of-flight mass spectrometry (MPI-TOFMS) combined with a pulsed laser for sample vaporization was developed for the detection of a low-volatile compound in a solution. A solution containing Taiwanin A ((3E,4E)-3,4-bis(1,3-benzodioxol-5-ylmethylene)dihydro-2(3H)-furanone), which is a lignan that has an anticancer effect, was employed in the present study. Consequently, Taiwanin A could be detected by irradiating a laser pulse for vaporization to an inlet nozzle, rather than by heating. Therefore, the present method could be effective for detecting compounds with lower volatilities in a liquid sample.

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Acknowledgements

This work was supported by a research grant provided by the Kurita Water and Environment Foundation.

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Authors and Affiliations

  1. Department of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui, 910-8507, Japan

    Tomohiro Uchimura & Goro Tokumoto

  2. Department of Frontier Fiber Technology and Science, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui, 910-8507, Japan

    Onon Batnyam & Satoshi Fujita

  3. Department of Cosmeceutic and Tsuzuki Institute for Traditional Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan, 40402, China

    Chih-Wei Chou

Authors
  1. Tomohiro Uchimura
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  2. Goro Tokumoto
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  3. Onon Batnyam
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  4. Chih-Wei Chou
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  5. Satoshi Fujita
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Correspondence to Tomohiro Uchimura.

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Uchimura, T., Tokumoto, G., Batnyam, O. et al. Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Bioactive Lignan. ANAL. SCI. 32, 255–257 (2016). https://doi.org/10.2116/analsci.32.255

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  • DOI: https://doi.org/10.2116/analsci.32.255

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