Abstract
A multi-functional eletrogenerated chemiluminescence (ECL) imaging analyzer including both a photomultiplier tube and charged coupled device as detectors has been developed. The ECL imaging analyzer can effectively work for electrochemical study, ECL intensity detection at electrode array, and ECL imaging at bipolar electrodes or electrode array. As an ECL imaging example, an ECL biosensor for visual detection of matrix metalloproteinase 7 in the range from 0.05 to 1 ng/mL is demonstrated.
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References
A. J. Bard, “Electrogenerated Chemiluminescence”, 2004, Marcel Dekker, New York.
M. M. Richter, Chem. Rev., 2004, 104, 3003.
W. Miao, Chem. Rev., 2008, 108, 2506.
R. J. Forster, P. Bertoncello, and T. E. Keyes, Annu. Rev. Anal. Chem., 2009, 2, 359.
L. Z. Hu and G. B. Xu, Chem. Soc. Rev., 2010, 39, 3275.
H. Qi, Y. Zhang, Y. Peng, and C. Zhang, Talanta, 2008, 75, 684.
Y. Li, Anal. Sci., 2011, 27, 193.
L. Zhang, Z. Xu, X. Sun, and S. Dong, Biosens. Bioelectron., 2007, 22, 1097.
X. B. Yin, S. J. Dong, and E. K. Wang, TrAC Trends Anal. Chem., 2004, 23, 432.
M. Sato and T. Yamada, Anal. Sci., 2006, 2, 529.
H. Yang, J. K. Leland, D. Yost, and R. J. Massey, Biotechnology, 1994, 12, 193.
Roche Diagnostics Corp., https://www.roche.com. Note: The initial Igen International and then BioVeris Corp. have now been acquired by Roche Diagnostics Corp.
Meso Scale Discovery, https://www.mesoscale.com.
Xi'an Remax Electronic Co. Ltd., http://remax.testmart.cn.
Bioveris Diagnostics, https://www.bioveris.com.
P. Pantano and W. G. Kuhr, Anal. Chem., 1991, 63, 1413.
R. G. Maus and R. M. Wightman, Anal. Chem., 2001, 73, 3993.
G. Valenti, M. Zangheri, S. E. Sansaloni, M. Mirasoli, A. Penicaud, A. Roda, and F. Paolucci, Chem. Eur. J., 2015, 21, 12640.
L. L. Shultz, J. S. Stoyanoff, and T. A. Nieman, Anal. Chem., 1996, 68, 349.
E. G. Hvastkovs, M. So, S. Krishnan, B. Bajrami, M. Tarun, I. Jansson, J. B. Schenkman, and J. F. Rusling, Anal. Chem., 2007, 79, 1897.
F. Deiss, C. N. LaFratta, M. Symer, T. M. Blicharz, N. Sojic, and D. R. Walt, J. Am. Chem. Soc., 2009, 131, 6088.
M. S. Wu, D. J. Yuan, J. J. Xu, and H. Y. Chen, Chem. Sci., 2013, 4, 1182.
J. Y. Zhou, G. Z. Ma, Y. Chen, D. J. Fang, D. C. Jiang, and H. Y. Chen, Anal. Chem., 2015, 87, 8138.
D. D. Zhang, Y. G. Peng, H. L. Qi, Q. Gao, and C. X. Zhang, Sens. Actuators, B, 2009, 136, 113.
H. R. Zhang, Y. Z. Wang, W. Zhao, J. J. Xu, and H. Y. Chen, Anal. Chem., 2016, 88, 2884.
X. Li, L. Shen, D. Zhang, H. Qi, Q. Gao, F. Ma, and C. Zhang, Biosens. Bioelectron., 2008, 23, 1624.
W. Miao, J. P. Choi, and A. J. Bard, J. Am. Chem. Soc., 2002, 124, 14478.
K.-F. Chow, F. Mavré, and R. M. Crooks, J. Am. Chem. Soc., 2008, 130, 7544.
G. Liu, J. Wang, D. S. Wunschel, and Y. Lin, J. Am. Chem. Soc., 2006, 128, 12382.
Acknowledgments
We thank the National Science Foundation of China (Nos. 21027007, 21275095, 21475082, 21522504), the Natural Science Basic Research Plan in Shaanxi Province of China (No. 2013SZS08-Z01 and 2013SZS08-P01) and the Fundamental Research Funds for the Central Universities (No. GK201603041).
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Jiang, G., Liu, X., Wang, Y. et al. Design and Application of Multi-functional Electrogenerated Chemiluminescence Imaging Analyzer. ANAL. SCI. 32, 1023–1027 (2016). https://doi.org/10.2116/analsci.32.1023
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DOI: https://doi.org/10.2116/analsci.32.1023