Abstract
Background
Since the first description of adult blaschkitis (AB), the existence of this entity has been a matter of great debate.
Objectives
To compare clinicopathological features of lichen striatus (LS) and AB cases. Materials and Methods: We retrospectively reviewed the clinicopathological features of patients who clinically showed linear inflammatory dermatosis along Blaschko’s lines based on a skin biopsy registry.
Results
Through a process of clinicopathological differential diagnosis, 27 cases of LS, three of AB, eight of linear lichen planus, and two of linear psoriasis were identified. Clinicopathological differences between LS and ABwere mostly insignificant except for age at onset and multiple site involvement. In these cases, females were affected more frequently than males. The mean age at onset was 31.6 years, and the most common involved site was the leg. The lesions lasted approximately 8.3 months with few relapses. The most common histopathological finding was perivascular infiltration followed by peri-appendageal infiltration.
Conclusion
Distinction between LS and AB appears to be unnecessary given their overlapping features.
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References
Hofer T. Lichen striatus in adults or ‘adult blaschkitis’? There is no need for a new naming. Dermatology 2003; 207: 89–92.
Charles CR, Johnson BL, Robinson TA. Lichen striatus - clinical, histologic and electron-microscopic study of an unusual case. J Cutan Pathol 1974; 1: 265–74.
Zhang YQ, McNutt NS. Lichen striatus - histological, immunohistochemical, and ultrastructural study of 37 cases. J Cutan Pathol 2001; 28: 65–71.
Zhou Y, Yu ZZ, Peng J, Yang PP, Li SJ, Fan YM. Lichen striatus versus linear lichen planus: a comparison of clinicopathological features, immunoprofile of infiltrated cells, and epidermal proliferation and differentiation. Int J Dermatol 2016; 55: E204–10.
Taieb A, el Youbi A, Grosshans E, Maleville J. Lichen striatus: a Blaschko linear acquired inflammatory skin eruption. J Am Acad Dermatol 1991; 25: 637–42.
Muller CS, Schmaltz R, Vogt T, Pfohler C. Lichen striatus and blaschkitis: reappraisal of the concept of blaschkolinear dermatoses. Br J Dermatol 2011; 164: 257–62.
Grosshans E, Marot L. Blaschkitis in adults. Ann Dermatol Venereol 1990; 117: 9–15.
Grosshans EM. Acquired blaschkolinear dermatoses. Am J Med Genet 1999; 85: 334–7.
Megahed M, Reinauer S, Scharffetter-Kochanek K, et al. Acquired relapsing self-healing Blaschko dermatitis. J Am Acad Dermatol 1994; 31: 849–52.
Lee HJ, Kang WH, Hann SK. Acquired Blaschko dermatitis: acquired relapsing self-healing Blaschko dermatitis. J Dermatol 1996; 23: 639–42.
Lipsker D, Stark J, Schneider GA. Blaschko-linear dermatitis in adulthood (Grosshans-Marot disease) with antinuclear antibodies. Hautarzt 2000; 51: 774–7.
Keegan BR, Kamino H, Fangman W, Shin HT, Orlow SJ, Schaffer JV. “Pediatric blaschkitis”: expanding the spectrum of childhood acquired Blaschko-linear dermatoses. Pediatric Dermatol 2007; 24: 621–7.
Reiter H, Feldmann R, Breier F, Happle R, Gschnait F. Lichen striatus or Blaschkitis in the adults. Variations of the same entity? Hautarzt 2000; 51: 770–3.
Suarez-Penaranda JM, Figueroa O, Rodriguez-Blanco I, Aliste C, Casas L. Unusual interface dermatoses distributed along Blaschko’s lines in adult patients. Am J Dermatopathol 2017; 39: 144–9.
Lenormand C, Cribier B, Lipsker D. Blaschko-linear manifestations of polygenic inflammatory diseases: analysis of 17 cases. Eur J Dermatol 2013; 23: 671–6.
Happle R, Lenz W. Striation of bones in focal dermal hypoplasia: manifestation of functional mosaicism? Br J Dermatol 1977; 96: 133–5.
Lipsker D, Cribier B, Girard-Lemaire F, Flori E, Grosshans E. Genetic mosaicism in an acquired inflammatory dermatosis following the lines of Blaschko. Arch Dermatol 2000; 136: 805–7.
Campanati A, Brandozzi G, Giangiacomi M, Simonetti O, Marconi B, Offidani AM. Lichen striatus in adults and pimecrolimus: open, off-label clinical study. Int J Dermatol 2008; 47: 732–6.
Taïeb A, Grosshans E. Lichen striatus. In: Harper’s Textbook of Pediatric Dermatology, Vol 1. 3rd Ed. Irvine AD, Hoeger PH, Yan AC. Wiley-Blackwell, 2011: 86.81–7.
Kus S, Ince U. Lichen striatus in an adult patient treated with pimecrolimus. J Eur Acad Dermatol Venereol 2006; 20: 360–1.
Ishikawa M, Ohashi T, Yamamoto T. Lichen striatus following influenza infection. J Dermatol 2014; 41: 1133–4.
Richarz NA, Fusta-Novell X, Fatsini-Blanch V, Fortuny C, Gonzalez-Ensenat MA, Vicente A. Lichen striatus following scarlet fever in a 3-year-old female patient. Int J Dermatol 2018; 57: 1118–9.
Hafner C, Landthaler M, Vogt T. Lichen striatus (blaschkitis) following varicella infection. J Eur Acad Dermatol Venereol 2006; 20: 1345–7.
Hwang SM, Ahn SK, Lee SH, Choi EH. Lichen striatus following BCG vaccination. Clin Exp Dermatol 1996; 21: 393–4.
Karakas M, Durdu M, Uzun S, Karakas P, Tuncer I, Cevlik F. Lichen striatus following HBV vaccination. J Dermatol 2005; 32: 506–8.
Karouni M, Kurban M, Abbas O. Lichen striatus following yellow fever vaccination in an adult woman. Clin Exp Dermatol 2017; 42: 823–4.
Unal E, Balta I, Bozkurt O. Lichen striatus: after a bite by bumblebee. Cutan Ocul Toxicol 2015; 34: 171–2.
Shepherd V, Lun K, Strutton G. Lichen striatus in an adult following trauma. Australas J Dermatol 2005; 46: 25–8.
Brennand S, Khan S, Chong AH. Lichen striatus in a pregnant woman. Australas J Dermatol 2005; 46: 184–6.
Mun JH, Park HJ, Kim HS, et al. Lichen striatus occurring after allogenic peripheral blood stem cell transplantation in an adult with aplastic anemia. Ann Dermatol 2012; 24: 87–9.
Monteagudo B, Cabanillas M, Suarez-Amor O, Ramirez-Santos A, Alvarez JC, de Las Heras C. Adult blaschkitis (lichen striatus) in a patient treated with adalimumab. Actas Dermosifiliogr 2010; 101: 891–2.
Lora V, Kanitakis J, Latini A, Cota C. Lichen striatus associated with etanercept treatment of rheumatoid arthritis. J Am Acad Dermatol 2014; 70: e90–2.
Plantin P, Le Noach E, Abgrall JF, Le Roy JP. Case for diagnosis: lichen striatus. Ann Dermatol Venereol 1993; 120: 251–2.
Mask-Bull L, Vangipuram R, Carroll BJ, Tarbox MB. Lichen striatus after interferon therapy. JAAD Case Rep 2015; 1: 254–6.
Brinkmeier T, Herbst RA, Schaller J, et al. Drug-induced blaschkitis. Acta Derm Venereol 2004; 84: 314–5.
Say M, Boralevi F, Lenormand C, et al. Clinical and therapeutic aspects of linear psoriasis: a study of 30 cases. Am J Clin Dermatol 2018; 19: 609–15.
Kim SJ, Kim YC. Linear psoriasis along Blaschko’s lines. Ann Dermatol 2017; 29: 106–7.
Sorgentini C, Allevato MA, Dahbar M, Cabrera H. Lichen striatus in an adult: successful treatment with tacrolimus. Br J Dermatol 2004; 150: 776–7.
Lee DY, Kim S, Kim CR, Kim HJ, Byun JY, Yang JM. Lichen striatus in an adult treated by a short course of low-dose systemic corticosteroid. J Dermatol 2011; 38: 298–9.
Saez-Rodriguez M, Rodriguez-Martin M, Carnerero-Rodriguez A, et al. Lichen striatus in an adult successfully treated with pimecrolimus cream. J Eur Acad Dermatol Venereol 2006; 2: 1140–1.
Funding
Disclosure. Funding sources: This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (NRF-2018R1D1A1B07045088). Conflicts of interest: none
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Baek, Y.S., Seo, J.Y., Seo, S.H. et al. Adult-onset lichen striatus versus adult blaschkitis: a clinicopathological review of 40 cases of acquired blaschkolinear inflammatory dermatosis. Eur J Dermatol 29, 281–286 (2019). https://doi.org/10.1684/ejd.2019.3556
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DOI: https://doi.org/10.1684/ejd.2019.3556