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Fabrication and characterization of Plantago psyllium mucilage/ chitosan composite scaffold: Physico-mechanical and antibacterial properties

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Abstract

Mucilage/ polymer hybrids are promising materials for biomedical applications and tissue engineering. Plantago psyllium mucilage/ chitosan composite scaffold was prepared by the freeze-drying method. The different ratio (v/v) of mucilage (2.5%, 5%) and chitosan (5%) was used to obtain the perfect scaffold with optimum properties. The scanning electron microscope images exhibited composite scaffolds have relatively large cylindrical porosity in which small spherical pores are enclosed and the porosity is reduced and come close to spherical shape by increasing the concentration of Plantago psyllium mucilage from 2.5% to 5%. The in vitro degradation studies showed the decreasing weight loss % with the addition of chitosan. Antibacterial activity of the obtained scaffolds against Escherichia coli and Staphylococcus aureus bacteria indicated acceptable activity against both of them.

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Acknowledgments

The authors would like to express their personal thanks to Islamic Azad University, Najafabad, Iran.

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Authors and Affiliations

  1. Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran

    Fereshteh Beheshti

  2. Department of Chemistry, Najafabad Branch, Islamic Azad University, Najafabad, Iran

    Hossein Abbastabar Ahangar

  3. Department of Biochemistry, Najafabad Branch, Islamic Azad University, Najafabad, Iran

    Elahe Poorazizi

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  1. Fereshteh Beheshti
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  2. Hossein Abbastabar Ahangar
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  3. Elahe Poorazizi
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Correspondence to Hossein Abbastabar Ahangar.

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Beheshti, F., Ahangar, H.A. & Poorazizi, E. Fabrication and characterization of Plantago psyllium mucilage/ chitosan composite scaffold: Physico-mechanical and antibacterial properties. Journal of Materials Research 37, 1440–1450 (2022). https://doi.org/10.1557/s43578-022-00544-y

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