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Outcomes of Immunosuppressed Patients Who Develop Melanoma: A Population-Based Propensity-Matched Cohort Study

  • Melanoma
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Introduction

Few studies have examined outcomes in immunosuppressed patients who develop melanoma. The purpose of this study is to compare survival in immunosuppressed patients who developed melanoma with that in patients with melanoma who are not immunosuppressed.

Methods

Immunosuppressed patients were defined as having solid organ transplant, lymphoma, leukemia, or human immunodeficiency virus prior to diagnosis of melanoma. Patients with cutaneous melanoma with and without immunosuppression were identified retrospectively from the Ontario Cancer Registry (2007–2015) and linked with administrative databases to identify demographics, treatment, and outcomes. Immunosuppressed patients were matched with non-immunosuppressed patients based on age at diagnosis, sex, birth year, stage at diagnosis, and propensity score. The primary outcome was overall survival. Multivariable Cox proportional hazard regression was used to identify factors associated with survival.

Results

Baseline characteristics were well balanced in 218 immunosuppressed patients matched to 436 controls. Of the patients, 186 (28.4%) were female, and median age at melanoma diagnosis was 69 (interquartile range, IQR 59–78) years. Three-year overall survival (OS) was 65% for immunosuppressed patients and 79% for non-immunosuppressed patients. Melanoma was the leading cause of death for both groups. On multivariable analysis, immunosuppression was associated with increased mortality [hazard ratio (HR) 1.70, 95% confidence interval (CI) 1.30–2.23]. Adequate treatment (HR 0.36, 95% CI 0.22–0.58) and dermatologist visits either before (HR 0.52, 95% CI 0.36–0.73) or after (HR 0.61, 95% CI 0.41–0.90) melanoma diagnosis were associated with improved OS.

Conclusions

Immunosuppressed patients who develop melanoma have worse outcomes when matched to non-immunosuppressed patients. This decrease in survival appears related to the underlying condition rather than diagnosis of melanoma.

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Acknowledgement

Academic Enrichment Fund for General Surgery at Sunnybrook Health Sciences Centre. Mahaffy Research Grant.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nicole J. Look Hong MD.

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None of the above authors have any conflicts of interest to declare.

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Appendix

Appendix

ICD-O-3 morphology and behavior codes for melanoma

Code

Description

8720/3

Malignant melanoma, NOS; melanoma, NOS

8721/3

Nodular melanoma

8722/3

Balloon cell melanoma

8723/3

Malignant melanoma, regressing

8728/3

Meningeal melanomatosis

8730/3

Amelanotic melanoma

8740/3

Malignant melanoma in junctional nevus

8741/3

Malignant melanoma in precancerous melanosis

8742/3

Lentigo maligna melanoma; Malignant melanoma in Hutchinson melanotic freckle

8743/3

Superficial spreading melanoma

8744/3

Acral lentiginous melanoma, malignant

8745/3

Desmoplastic melanoma, malignant; Neurotropic melanoma, malignant; Desmoplastic melanoma, amelanotic

8746/3

Mucosal lentiginous melanoma

8761/3

Malignant melanoma in giant pigmented nevus; Malignant melanoma in congenital melanocytic nevus

8770/3

Mixed epithelioid and spindle cell melanoma

8771/3

Epithelioid cell melanoma

8772/3

Spindle cell melanoma, NOS

8773/3

Spindle cell melanoma, type A

8774/3

Spindle cell melanoma, type B

ICD-O-3 topography codes

Code

Description

C00.0

External upper lip

C00.1

External lower lip

C44.0

Skin of lip, NOS

C44.1

Eyelid

C44.2

External ear

C44.3

Skin of other and unspecified parts of face

C44.4

Skin of scalp and neck

C44.5

Skin of trunk

C44.6

Skin of upper limb and shoulder

C44.7

Skin of lower limp and hip

C44.8

Overlapping lesion of skin

C44.9

Skin, NOS

C49.0

Connective, subcutaneous, and other soft tissues of head, face, and neck

C49.1

Connective, subcutaneous, and other soft tissues of upper limb and shoulder

C49.2

Connective, subcutaneous, and other soft tissues of lower limb and hip

C49.3

Connective, subcutaneous, and other soft tissues of thorax

C49.9

Connective, subcutaneous, and other soft tissues, NOS

C50.1

Central portion of breast

C50.9

Breast, NOS

C51.0

Labium majus

C51.1

Labium minus

C51.2

Clitoris

C60.0

Prepuce

C60.9

Penis, NOS

C63.2

Scrotum, NOS

C77.3

Lymph nodes of axilla or arm

C77.4

Lymph nodes of inguinal region or leg

C77.9

Lymph node, NOS

Morphology Codes for Lymphoma

9590/3 9591/3 9596/3 9597/3 9650/3 9651/3 9652/3 9653/3 9654/3 9655/3 9659/3 9663/3 9664/3 9665/3 9667/3 9670/3 9671/3 9673/3 9675/3 9678/3 9679/3 9680/3 9684/3 9687/3 9688/3 9689/3 9690/3 9691/3 9695/3 9698/3 9699/3 9700/3 9702/3 9705/3 9708/3 9709/3 9712/3 9714/3 9716/3 9717/3 9718/3 9719/3 9725/3 9726/3 9735/3 9737/3 9738/3

Morphology Codes for Leukemia

9742/3 9800/3 9801/3 9805/3 9806/3 9807/3 9808/3 9809/3 9811/3 9812/3 9813/3 9814/3 9815/3 9816/3 9817/3 9818/3 9820/3 9823/3 9826/3 9827/3 9831/3 9832/3 9833/3 9834/3 9840/3 9860/3 9861/3 9863/3 9865/3 9866/3 9867/3 9869/3 9870/3 9871/3 9872/3 9873/3 9874/3 9875/3 9876/3 9891/3 9895/3 9896/3 9897/3 9897/3 9910/3 9911/3 9940/3 9945/3 9946/3 9948/3

Consultation OHIP fee codes

Code

Fee code description

A025

CONSULT.-DERM

A035

CONSULT.-GEN. SURG

A085

CONSULT.-PLASTIC SURG

Surgical OHIP fee codes

Excision

Code

Fee code description

R010

WIDE EXCISION MALIGNANT MELANOMA

R081

SURG PROC-SKIN-SURGERY (M.O.H’S TECHNIQUE)

R990

SURGICAL PROCEDURE-NOT SPECIFICALLY LISTED-I.C

Sentinel lymph node biopsy

Code

Fee code description

Z427

Sentinel node biopsy, per draining basin

R914

LYMPHATIC-NODES-EXC.AUXILLARY/INGUINAL LIMITED

Lymph node dissection

Code

Fee code description

R912

LYMPHATIC-NODES-EXC.ILEOINGUINAL-RADICAL

R913

LYMPHATIC-NODES-EXC.-AXILLARY, INGUINAL-RADICAL RESECTION

J661

NUCLEAR MED. LYMPHANGIOGRAM

J861

NUCLEAR MED. CORRES. TO J661

Neck dissection

Code

Fee code description

R910

LYMPHATIC-NODES-EXC.-NECK-LIMITED

R915

LYMPHATIC NODES-EXC.-MODIFIED RADICAL-PRESERV.SPIN.ACC NERVE

Flap

Code

Fee code description

E227

TEMPORAL ROTATIONAL FLAP-EYELIDS

R002

SKIN-ADV. FLAPS-OTHER AREAS-DEFECT-2.1-5 CM.

R003

SKIN-ADV. FLAPS-OTHER AREAS-DEFECT-5.1-10 CM.

R004

SKIN-ADV. FLAPS-OTHER AREAS-DEFECT OVER 10 CM.

R005

SKIN-MYOCUTAN.FLAP-INCL.CLOS-STERNOMASTOID/TENSOR FASC. LATA

R011

SKIN-ADV.FLAPS-FACE/NECK/SCALP DEFECT 2.1CM-5CM

R012

SKIN-ADV.FLAPS-FACE/NECK/SCALP DEFECT 5.1CM-10CM.

R045

SKIN-ROT’N/TRANS./Z PLASTY FACE/NECK/SCALP UP TO 2CM

R046

SKIN-ROT’N/TRANS./Z PLASTY FACE/NECK/SCALP 2.1CM TO 5CM

R047

SKIN-ROT’N/TRANS./Z PLASTY FACE/NECK/SCALP 5.1CM TO 10CM

R072

SKIN-FLAPS-ROT/TRANS/ZPLASTY-OTHER AREAS-LESS THAN 2CM DIAM.

R073

SKIN-FLAPS-ROT/TRANS/ZPLASTY-OTHER AREAS-5.1-10 CM.DIAM.

R074

SKIN-FLAPS/ROTATIONS/TRANSPOSIT/ZPLASTY MORE THAN 10CM DIAM.

R075

SKIN-FLAPS-ROT/TRANS/ZPLASTY-OTHER AREAS-2.1-5 CM.DIAM.

R076

SKIN FLAPS—DEFECT MORE THAN 10 CM AVE. DIAM.—FACE/NECK/S

Graft

Code

Fee code description

R083

SKIN-FULL THICKNESS GRAFT-MAJOR-OVER 5CM DIAMETER

R085

SKIN-SPLIT THICKNESS GRAFT-MINOR, MEDIUM AREA

R086

SKIN-SPLIT THICKNESS GRAFT-INTERMEDIATE, LARGE AREAS

R087

SKIN-SPLIT THICKNESS GRAFT-MAJOR-COMPLEX AREA

R088

SKIN-SPLIT THICKNESS GRAFT-EXT-MAJOR-LARGE AREAS

R091

SKIN-FULL THICKNESS GRAFT-COMPLEX-EYELID, NOSE, LIP, FACE

R093

SKIN-FULL THICKNESS GRAFT-INTERMED.-1-5 CM.

Amputation

Code

Fee code description

E102

EYEBALL-EXC.-ENUCLEATION

R606

EXTREMITIES-AMPUTATION-THROUGH PHALANX-UPPER

R610

EXTREMITIES-AMPUTATION-TRANS METACARPAL-2ND OR 5TH RAY

R620

EXTREMITIES-AMPUTATION-LOWER-THROU.METATARSAL/M.P.JOINTS

R621

EXTREMITIES-AMPUTATION -RAY SINGLE

R622

EXTREMITIES-AMPUTATION -TRANSMETATARSAL/TRANSTARSAL

CCI procedure codes

Code

Fee code description

1.CX.80

Repair, eyelid NEC

1.CX.80.UD

Repair, eyelid NEC no tissue used (for repair) using full-thickness repair (involving lid margin)

1.CX.80.UD-XX-A

Repair, eyelid NEC with autograft using full-thickness repair (involving lid margin)

1.CX.80.UD-XX-E

Repair, eyelid NEC with local flap [e.g., Zplasty] using full-thickness repair (involving lid margin)

1.CX.80.VP

Repair, eyelid NEC no tissue used (for repair) using partial-thickness repair (involving lid margin)

1.CX.80.VP-XX-A

Repair, eyelid NEC with autograft using partial-thickness repair (involving lid margin)

1.CX.80.VP-XX-E

Repair, eyelid NEC with local flap [e.g., Zplasty] using partial-thickness repair (involving lid margin)

1.CX.80.WJ-XX-A

Repair, eyelid NEC with autograft using excision technique

1.CX.80.WJ-XX-E

Repair, eyelid NEC with local flap [e.g., Zplasty] using excision technique

1.CX.87

Excision partial, eyelid NEC

1.CX.87.LA-XX-A

Excision partial, eyelid NEC with autograft using simple excision

1.CX.87.LA-XX-K

Excision partial, eyelid NEC with homograft [e.g., amniotic membrane transplant (AMT) or graft] using simple excision

1.CX.87.UD

Excision partial, eyelid NEC no tissue used (for repair) using full-thickness excision of lesion (more than one-fourth of lid margin)

1.CX.87.UD-XX-A

Excision partial, eyelid NEC with autograft full-thickness excision of lesion (more than one-fourth of lid margin)

1.CX.87.UD-XX-K

Excision partial, eyelid NEC with homograft [e.g., amniotic membrane transplant (AMT) or graft] full-thickness excision of lesion (more than one-fourth of lid margin)

1.CX.87.VP-XX-A

Excision partial, eyelid NEC with autograft partial-thickness excision of lesion (up to one-fourth of lid margin)

1.CX.87.VP-XX-K

Excision partial, eyelid NEC with homograft [e.g., amniotic membrane transplant (AMT) or graft] partial-thickness excision of lesion (up to one-fourth of lid margin)

1.MA.52.LA

Drainage, lymph node(s), head region using open approach

1.MA.87.LA

Excision partial, lymph node(s), head region using open approach

1.MC.52.LA

Drainage, lymph node(s), neck region NEC (cervical) using open approach

1.MC.87.LA

Excision partial, lymph node(s), neck region NEC (cervical) using open approach with no tissue

1.MC.87.LA-XX-A

Excision partial, lymph node(s), neck region NEC (cervical) using open approach with full-thickness graft

1.MC.87.LA-XX-E

Excision partial, lymph node(s), neck region NEC (cervical) using open approach with local flap

1.MC.87.LA-XX-F

Excision partial, lymph node(s), neck region NEC (cervical) using open approach with free distant flap

1.MC.87.LA-XX-G

Excision partial, lymph node(s), neck region NEC (cervical) using open approach with pedicled distant flap

1.MC.87.LA-XX-N

Excision partial, lymph node(s), neck region NEC (cervical) using open approach with synthetic tissue

1.MC.89.LA

Excision total, lymph node(s), neck region NEC (cervical) using open approach with no tissue

1.MC.89.LA-XX-A

Excision total, lymph node(s), neck region NEC (cervical) using open approach with full-thickness graft

1.MC.89.LA-XX-E

Excision total, lymph node(s), neck region NEC (cervical) using open approach with local flap

1.MC.89.LA-XX-F

Excision total, lymph node(s), neck region NEC (cervical) using open approach with free distant flap

1.MC.89.LA-XX-G

Excision total, lymph node(s), neck region NEC (cervical) using open approach with pedicled distant flap

1.MC.89.LA-XX-N

Excision total, lymph node(s), neck region NEC (cervical) using open approach with synthetic tissue

1.MC.91.LA

Excision radical, lymph node(s). neck region NEC (cervical) without tissue radical neck dissection (1)

1.MC.91.LA-XX-A

Excision radical, lymph node(s). neck region NEC (cervical) using full-thickness graft radical neck dissection

1.MC.91.LA-XX-E

Excision radical, lymph node(s). neck region NEC (cervical) using local flap radical neck dissection (1)

1.MC.91.LA-XX-F

Excision radical, lymph node(s). neck region NEC (cervical) using free distant flap radical neck dissection (1)

1.MC.91.LA-XX-G

Excision radical, lymph node(s). neck region NEC (cervical) using pedicled distant flap radical neck dissection (1)

1.MC.91.VB

Excision radical, lymph node(s). neck region NEC (cervical) without tissue modified radical neck dissection (2)

1.MC.91.VB-XX-A

Excision radical, lymph node(s). neck region NEC (cervical) using full-thickness graft modified radical neck dissection

1.MC.91.VB-XX-E

Excision radical, lymph node(s). neck region NEC (cervical) using local flap modified radical neck dissection (2)

1.MC.91.VB-XX-F

Excision radical, lymph node(s). neck region NEC (cervical) using free distant flap modified radical neck dissection (2)

1.MC.91.VB-XX-G

Excision radical, lymph node(s). neck region NEC (cervical) using pedicled distant flap modified radical neck dissection (2)

1.MD.52.LA

Drainage, lymph node(s), axillary using open approach

1.MD.87.LA

Excision partial, lymph node(s), axillary using open approach

1.MD.89.LA

Excision total, lymph node(s), axillary using open approach

1.MD.89.LA-XX-A

Excision total, lymph node(s), axillary using open approach with full-thickness graft

1.MD.89.LA-XX-E

Excision total, lymph node(s), axillary using open approach with local flap

1.MD.89.LA-XX-F

Excision total, lymph node(s), axillary using open approach with free distant flap

1.MD.89.LA-XX-G

Excision total, lymph node(s), axillary using open approach with pedicled distant flap

1.MD.89.LA-XX-N

Excision total, lymph node(s), axillary using open approach with synthetic tissue

1.MH.52.DA

Drainage, lymph node(s), pelvic using endoscopic approach

1.MH.52.LA

Drainage, lymph node(s), pelvic using open approach

1.MH.87.DA

Excision partial, lymph node(s), pelvic using endoscopic approach

1.MH.87.LA

Excision partial, lymph node(s), pelvic using open approach

1.MH.89.DA

Excision total, lymph node(s), pelvic using endoscopic approach

1.MH.89.LA

Excision total, lymph node(s), pelvic using open approach

1.MJ.52.LA

Drainage, lymph node(s), inguinal using open approach

1.MJ.87.DA

Excision partial, lymph node(s), inguinal using endoscopic approach

1.MJ.87.LA

Excision partial, lymph node(s), inguinal using open approach

1.MJ.89.DA

Excision total, lymph node(s), inguinal using endoscopic approach

1.MJ.89.LA

Excision total, lymph node(s), inguinal using open approach

1.MJ.91.LA-XX-A

Excision radical, lymph node(s), inguinal using open approach with full-thickness graft

1.MJ.91.LA-XX-E

Excision radical, lymph node(s), inguinal using open approach with local flap

1.MJ.91.LA-XX-F

Excision radical, lymph node(s), inguinal using open approach with free distant flap

1.MJ.91.LA-XX-G

Excision radical, lymph node(s), inguinal using open approach with pedicled distant flap

1.MJ.91.LA-XX-N

Excision radical, lymph node(s), inguinal using open approach with synthetic tissue

1.UI.93

Amputation, first phalanx of hand

1.UI.93.LA

Amputation, first phalanx of hand using simple apposition technique [e.g., suturing] (for closure of stump)

1.UI.93.LA-XX-A

Amputation, first phalanx of hand using autograft [e.g., full-thickness skin graft or bone graft] (for closure of stump)

1.UI.93.LA-XX-B

Amputation, first phalanx of hand using split-thickness skin graft (for closure of stump)

1.UI.93.LA-XX-E

Amputation, first phalanx of hand using local flap [e.g., V–Y plasty]

1.UI.93.LA-XX-F

Amputation, first phalanx of hand using free flap [e.g., toe-to-finger flap]

1.UI.93.LA-XX-G

Amputation, first phalanx of hand using pedicled transposition flap [e.g., finger rotation flap]

1.UJ.93

Amputation, phalanx of hand

1.UJ.93.LA

Amputation, other phalanx of hand using simple apposition technique [e.g., suturing] (for closure of stump)

1.UJ.93.LA-XX-A

Amputation, other phalanx of hand using autograft [e.g., full-thickness skin graft or bone graft] (for closure of stump)

1.UJ.93.LA-XX-B

Amputation, other phalanx of hand using split-thickness skin graft (for closure of stump)

1.UJ.93.LA-XX-E

Amputation, other phalanx of hand using local flap [e.g., V–Y plasty]

1.UJ93.LA-XX-F

Amputation, other phalanx of hand using free flap [e.g., toe-to-finger flap]

1.UJ93.LA-XX-G

Amputation, other phalanx of hand using pedicled transposition flap [e.g., finger rotation flap]

1.WI.93

Amputation, first metatarsal bone and first metatarsophalangeal joint

1.WI.93.LA

Amputation, first metatarsal bone and first metatarsophalangeal joint using open approach (with or without simple apposition for closure of stump)

1.WI.93.LA-XX-A

Amputation, first metatarsal bone and first metatarsophalangeal joint using skin autograft (for closure of stump)

1.WI.93.LA-XX-E

Amputation, first metatarsal bone and first metatarsophalangeal joint using local flap (for closure of stump)

1.WJ.93

Amputation, tarsometatarsal joints, metatarsal bones and metatarsophalangeal joints [forefoot]

1.WJ.93.LA

Amputation, tarsometatarsal joints, other metatarsal bones and other metatarsophalangeal joints [forefoot] using open approach (with or without simple apposition for closure of stump)

1.WJ.93.LA-XX-A

Amputation, tarsometatarsal joints, other metatarsal bones and other metatarsophalangeal joints [forefoot] using skin autograft (for closure of stump)

1.WJ.93.LA-XX-E

Amputation, tarsometatarsal joints, other metatarsal bones and other metatarsophalangeal joints [forefoot] using local flap (for closure of stump)

1.WK.93

Amputation, first phalanx of foot

1.WK.93.LA

Amputation, first phalanx of foot using simple apposition technique [e.g., suturing] (for closure of stump)

1.WK.93.LA-XX-A

Amputation, first phalanx of foot using skin graft (for closure of stump)

1.WK.93.LA-XX-G

Amputation, first phalanx of foot using pedicled transposition flap [e.g., toe rotation flap]

1.WL.93

Amputation, phalanx of foot

1.WL.93.LA

Amputation, other phalanx of foot using simple apposition technique [e.g., suturing] (for closure of stump)

1.WL.93.LA-XX-A

Amputation, other phalanx of foot using skin graft (for closure of stump)

1.WL.93.LA-XX-G

Amputation, other phalanx of foot using pedicled transposition flap [e.g., toe rotation flap]

1.YA.80

Repair, scalp

1.YA.80.JA-XX-K

Repair, scalp using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YA.80.JA-XX-P

Repair, scalp using cultured tissue

1.YA.80.LA-XX-A

Repair, scalp using full-thickness autograft

1.YA.80.LA-XX-B

Repair, scalp using split-thickness autograft

1.YA.80.LA-XX-E

Repair, scalp using local flap [e.g., rotation, advancement, juri, Z-plasty]

1.YA.80.LA-XX-F

Repair, scalp using free flap [e.g., fasciocutaneous]

1.YA.87

Excision partial, scalp

1.YA.87.LA-AY-A

Excision partial, scalp open [excisional] approach and dermatome using full-thickness autograft

1.YA.87.LA-AY-B

Excision partial, scalp open [excisional] approach and dermatome using split-thickness autograft

1.YA.87.LA-AY-E

Excision partial, scalp open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YA.87.LA-AY-F

Excision partial, scalp open [excisional] approach and dermatome using free flap

1.YA.87.LA-XX-A

Excision partial, scalp open [excisional] approach using full-thickness autograft

1.YA.87.LA-XX-B

Excision partial, scalp open [excisional] approach using split-thickness autograft

1.YA.87.LA-XX-E

Excision partial, scalp open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YA.87.LA-XX-F

Excision partial, scalp open [excisional] approach using free flap

1.YB.80

Repair, skin of forehead

1.YB.80.JA-XX-K

Repair, skin of forehead using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YB.80.JA-XX-P

Repair, skin of forehead using cultured tissue

1.YB.80.LA-XX-A

Repair, skin of forehead using full-thickness autograft

1.YB.80.LA-XX-B

Repair, skin of forehead using split-thickness autograft

1.YB.80.LA-XX-E

Repair, skin of forehead using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YB.80.LA-XX-F

Repair, skin of forehead using free flap [e.g., microvascular free flap]

1.YB.87

Excision partial, skin of forehead

1.YB.87.LA-AY-A

Excision partial, skin of forehead open [excisional] approach and dermatome using full-thickness autograft

1.YB.87.LA-AY-B

Excision partial, skin of forehead open [excisional] approach and dermatome using split-thickness autograft

1.YB.87.LA-AY-E

Excision partial, skin of forehead open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YB.87.LA-AY-F

Excision partial, skin of forehead open [excisional] approach and dermatome using free flap

1.YB.87.LA-AY-P

Excision partial, skin of forehead open [excisional] approach and dermatome using cultured tissue

1.YB.87.LA-XX-A

Excision partial, skin of forehead open [excisional] approach using full-thickness autograft

1.YB.87.LA-XX-B

Excision partial, skin of forehead open [excisional] approach using split-thickness autograft

1.YB.87.LA-XX-E

Excision partial, skin of forehead open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YB.87.LA-XX-F

Excision partial, skin of forehead open [excisional] approach using free flap

1.YB.87.LA-XX-P

Excision partial, skin of forehead open [excisional] approach using cultured tissue

1.YC.80

Repair, skin of ear

1.YC.80.JA-XX-K

Repair, skin of ear using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YC.80.JA-XX-P

Repair, skin of ear using cultured tissue

1.YC.80.LA-XX-A

Repair, skin of ear using full-thickness autograft

1.YC.80.LA-XX-B

Repair, skin of ear using split-thickness autograft

1.YC.80.LA-XX-E

Repair, skin of ear using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YC.87

Excision partial, skin of ear

1.YC.87.LA-XX-A

Excision partial, skin of ear open [excisional] approach using full-thickness autograft

1.YC.87.LA-XX-B

Excision partial, skin of ear open [excisional] approach using split-thickness autograft

1.YC.87.LA-XX-E

Excision partial, skin of ear open [excisional] approach using local flap

1.YD.80

Repair, skin of nose

1.YD.80.JA-XX-K

Repair, skin of nose using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YD.80.JA-XX-P

Repair, skin of nose using cultured tissue

1.YD.80.LA-XX-A

Repair, skin of nose using full-thickness autograft

1.YD.80.LA-XX-B

Repair, skin of nose using split-thickness autograft

1.YD.80.LA-XX-E

Repair, skin of nose using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YD.80.LA-XX-F

Repair, skin of nose using free flap

1.YD.87

Excision partial, skin of nose

1.YD.87.LA-AY-A

Excision partial, skin of nose open [excisional] approach and dermatome using full-thickness autograft

1.YD.87.LA-AY-B

Excision partial, skin of nose open [excisional] approach and dermatome using split-thickness autograft

1.YD.87.LA-AY-E

Excision partial, skin of nose open [excisional] approach and dermatome using local flap [e.g., advancement flap]

1.YD.87.LA-XX-A

Excision partial, skin of nose open [excisional] approach using full-thickness autograft

1.YD.87.LA-XX-B

Excision partial, skin of nose open [excisional] approach using split-thickness autograft

1.YD.87.LA-XX-E

Excision partial, skin of nose open [excisional] approach using local flap [e.g., advancement, transposition or rotation flap]

1.YE.80

Repair, lip

1.YE.80.LA-XX-A

Repair, lip using full-thickness autograft

1.YE.80.LA-XX-B

Repair, lip using split-thickness autograft

1.YE.80.LA-XX-E

Repair, lip using local flap [e.g., rotation, advancement, transposition, Zplasty, Millard]

1.YE.80.LA-XX-K

Repair, lip using homograft (e.g., alloderm)

1.YE.87

Excision partial, lip

1.YE.87.LA-XX-E

Excision partial, lip using open [excisional] approach with local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YE.87.WJ

Excision partial, lip using open wedge resection approach with apposition technique (e.g., suture, glue) for closure

1.YE.87.WJ-XX-E

Excision partial, lip using open wedge resection with local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YF.80

Repair, skin of face

1.YF.80.JA-XX-K

Repair, skin of face using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YF.80.JA-XX-P

Repair, skin of face using cultured tissue

1.YF.80.LA

Repair, skin of face using apposition technique [suture]

1.YF.80.LA-XX-A

Repair, skin of face using full-thickness autograft

1.YF.80.LA-XX-B

Repair, skin of face using split-thickness autograft

1.YF.80.LA-XX-E

Repair, skin of face using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YF.80.LA-XX-F

Repair, skin of face using free flap [e.g., microvascular free flap]

1.YF.80.LA-XX-G

Repair, skin of face using pedicled flap

1.YF.87

Excision partial, skin of face

1.YF.87.LA

Excision partial, skin of face open [excisional] approach with apposition technique (e.g., suture, glue) for closure

1.YF.87.LA-AY

Excision partial, skin of face open [excisional] approach and dermatome with apposition technique (e.g., suture, glue) for closure

1.YF.87.LA-AY-A

Excision partial, skin of face open [excisional] approach and dermatome using full-thickness autograft

1.YF.87.LA-AY-B

Excision partial, skin of face open [excisional] approach and dermatome using split-thickness autograft

1.YF.87.LA-AY-E

Excision partial, skin of face open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YF.87.LA-AY-F

Excision partial, skin of face open [excisional] approach and dermatome using free flap for closure

1.YF.87.LA-XX-A

Excision partial, skin of face open [excisional] approach using full-thickness autograft

1.YF.87.LA-XX-B

Excision partial, skin of face open [excisional] approach using split-thickness autograft

1.YF.87.LA-XX-E

Excision partial, skin of face open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YF.87.LA-XX-F

Excision partial, skin of face open [excisional] approach using free flap for closure

1.YG.80

Repair, skin of neck

1.YG.80.JA-XX-K

Repair, skin of neck using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YG.80.JA-XX-P

Repair, skin of neck using cultured tissue

1.YG.80.LA

Repair, skin of neck using apposition technique [suture]

1.YG.80.LA-XX-A

Repair, skin of neck using full-thickness autograft

1.YG.80.LA-XX-B

Repair, skin of neck using split-thickness autograft

1.YG.80.LA-XX-E

Repair, skin of neck using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YG.80.LA-XX-F

Repair, skin of neck using free flap [e.g., microvascular free flap]

1.YG.87

Excision partial, skin of neck

1.YG.87.LA

Excision partial, skin of neck open [excisional] approach with apposition technique (e.g., suture, glue) for closure

1.YG.87.LA-AY

Excision partial, skin of neck open [excisional] approach and dermatome with apposition technique (e.g., suture, glue) for closure

1.YG.87.LA-AY-A

Excision partial, skin of neck open [excisional] approach and dermatome using full-thickness autograft

1.YG.87.LA-AY-B

Excision partial, skin of neck open [excisional] approach and dermatome using split-thickness autograft

1.YG.87.LA-AY-E

Excision partial, skin of neck open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YG.87.LA-AY-F

Excision partial, skin of neck open [excisional] approach and dermatome using free flap

1.YG.87.LA-XX-A

Excision partial, skin of neck open [excisional] approach using full-thickness autograft

1.YG.87.LA-XX-B

Excision partial, skin of neck open [excisional] approach using split-thickness autograft

1.YG.87.LA-XX-E

Excision partial, skin of neck open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YG.87.LA-XX-F

Excision partial, skin of neck open [excisional] approach using free flap

1.YR.80

Repair, skin of axillary region

1.YR.80.JA-FF

Repair, skin of axillary region using closure device (e.g., clip, adhesive skin closure [Steri-Strips])

1.YR.80.JA-XX-K

Repair, skin of axillary region using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YR.80.JA-XX-P

Repair, skin of axillary region using cultured tissue

1.YR.80.LA

Repair, skin of axillary region using apposition technique [suture]

1.YR.80.LA-XX-A

Repair, skin of axillary region using full-thickness autograft

1.YR.80.LA-XX-B

Repair, skin of axillary region using split-thickness autograft

1.YR.80.LA-XX-E

Repair, skin of axillary region using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YR.80.LA-XX-F

Repair, skin of axillary region using free flap [e.g., microvascular free flap]

1.YR.87

Excision partial, skin of axillary region

1.YR.87.LA

Excision partial, skin of axillary region open [excisional] approach with apposition technique (e.g., suture, glue) for closure

1.YR.87.LA-AY

Excision partial, skin of axillary region open [excisional] approach and dermatome with apposition technique (e.g., suture, glue) for closure

1.YR.87.LA-AY-A

Excision partial, skin of axillary region open [excisional] approach and dermatome using full-thickness autograft

1.YR.87.LA-AY-B

Excision partial, skin of axillary region open [excisional] approach and dermatome using split-thickness autograft

1.YR.87.LA-AY-E

Excision partial, skin of axillary region open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YR.87.LA-XX-A

Excision partial, skin of axillary region open [excisional] approach using full-thickness autograft

1.YR.87.LA-XX-B

Excision partial, skin of axillary region open [excisional] approach using split-thickness autograft

1.YR.87.LA-XX-E

Excision partial, skin of axillary region open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YS.80

Repair, skin of abdomen and trunk

1.YS.80.JA-FF

Repair, skin of abdomen and trunk using closure device (e.g., clip, adhesive skin closure [Steri-Strips])

1.YS.80.JA-XX-K

Repair, skin of abdomen and trunk using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YS.80.JA-XX-P

Repair, skin of abdomen and trunk using cultured tissue

1.YS.80.LA

Repair, skin of abdomen and trunk using apposition technique [suture]

1.YS.80.LA-XX-A

Repair, skin of abdomen and trunk using full-thickness autograft

1.YS.80.LA-XX-B

Repair, skin of abdomen and trunk using split-thickness autograft

1.YS.80.LA-XX-E

Repair, skin of abdomen and trunk using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YS.80.LA-XX-F

Repair, skin of abdomen and trunk using free flap [e.g., fasciocutaneous free flap]

1.YS.87

Excision partial, skin of abdomen and trunk

1.YS.87.LA

Excision partial, skin of abdomen and trunk open [excisional] approach with apposition technique (suture, glue) for closure

1.YS.87.LA-AY

Excision partial, skin of abdomen and trunk open [excisional] approach and dermatome with apposition technique (suture, glue) for closure

1.YS.87.LA-AY-A

Excision partial, skin of abdomen and trunk open [excisional] approach and dermatome using full-thickness autograft

1.YS.87.LA-AY-B

Excision partial, skin of abdomen and trunk open [excisional] approach and dermatome using split-thickness autograft

1.YS.87.LA-AY-E

Excision partial, skin of abdomen and trunk open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YS.87.LA-AY-F

Excision partial, skin of abdomen and trunk open [excisional] approach and dermatome using free flap

1.YS.87.LA-XX-A

Excision partial, skin of abdomen and trunk open [excisional] approach using full-thickness autograft

1.YS.87.LA-XX-B

Excision partial, skin of abdomen and trunk open [excisional] approach using split-thickness autograft

1.YS.87.LA-XX-E

Excision partial, skin of abdomen and trunk open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YS.87.LA-XX-F

Excision partial, skin of abdomen and trunk open [excisional] approach using free flap

1.YT.80

Repair, skin of arm

1.YT.80.JA-FF

Repair, skin of arm using closure device (e.g., clip, adhesive skin closure [Steri-Strips])

1.YT.80.JA-XX-K

Repair, skin of arm using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YT.80.JA-XX-P

Repair, skin of arm using cultured tissue

1.YT.80.LA

Repair, skin of arm using apposition technique [suture]

1.YT.80.LA-XX-A

Repair, skin of arm using full-thickness autograft

1.YT.80.LA-XX-B

Repair, skin of arm using split-thickness autograft

1.YT.80.LA-XX-E

Repair, skin of arm using local flap [e.g., rotational, V Y advancement, transposition, Z plasty, Cutler flap]

1.YT.80.LA-XX-F

Repair, skin of arm using free flap [e.g., microvascular free flap]

1.YT.80.LA-XX-G

Repair, skin of arm using pedicled (distant)flap

1.YT.87

Excision partial, skin of arm

1.YT.87.LA

Excision partial, skin of arm open [excisional] approach with apposition technique (suture, glue) for closure

1.YT.87.LA-AY

Excision partial, skin of arm open [excisional] approach and dermatome with apposition technique (suture, glue) for closure

1.YT.87.LA-AY-A

Excision partial, skin of arm open [excisional] approach and dermatome using full-thickness autograft

1.YT.87.LA-AY-B

Excision partial, skin of arm open [excisional] approach and dermatome using split-thickness autograft

1.YT.87.LA-AY-E

Excision partial, skin of arm open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YT.87.LA-AY-F

Excision partial, skin of arm open [excisional] approach and dermatome using free flap

1.YT.87.LA-XX-A

Excision partial, skin of arm open [excisional] approach using full-thickness autograft

1.YT.87.LA-XX-B

Excision partial, skin of arm open [excisional] approach using split-thickness autograft

1.YT.87.LA-XX-E

Excision partial, skin of arm open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YT.87.LA-XX-F

Excision partial, skin of arm open [excisional] approach using free flap

1.YU.80

Repair, skin of hand

1.YU.80.JA-XX-K

Repair, skin of hand using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YU.80.JA-XX-P

Repair, skin of hand using cultured tissue

1.YU.80.LA-XX-A

Repair, skin of hand using full-thickness autograft

1.YU.80.LA-XX-B

Repair, skin of hand using split-thickness autograft

1.YU.80.LA-XX-E

Repair, skin of hand using local flap [e.g., rotational, V Y advancement, transposition, Z plasty, Cutler flap]

1.YU.80.LA-XX-F

Repair, skin of hand using free flap

1.YU.80.LA-XX-G

Repair, skin of hand using pedicled (distant) flap

1.YU.87

Excision partial, skin of hand

1.YU.87.LA-XX-A

Excision partial, skin of hand open [excisional] approach using full-thickness autograft

1.YU.87.LA-XX-B

Excision partial, skin of hand open [excisional] approach using split-thickness autograft

1.YU.87.LA-XX-E

Excision partial, skin of hand open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YU.87.LA-XX-F

Excision partial, skin of hand open (excisional) approach using free flap

1.YV.80

Repair, skin of leg

1.YV.80.JA-FF

Repair, skin of leg using closure device (e.g., clip, adhesive skin closure [Steri-Strips])

1.YV.80.JA-XX-K

Repair, skin of leg using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YV.80.JA-XX-P

Repair, skin of leg using cultured tissue

1.YV.80.LA

Repair, skin of leg using apposition technique [suture]

1.YV.80.LA-XX-A

Repair, skin of leg using full-thickness autograft

1.YV.80.LA-XX-B

Repair, skin of leg using split-thickness autograft

1.YV.80.LA-XX-E

Repair, skin of leg using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YV.80.LA-XX-F

Repair, skin of leg using free flap [e.g., fasciocutaneous flap]

1.YV.87

Excision partial, skin of leg

1.YV.87.LA

Excision partial, skin of leg open [excisional] approach with apposition technique (suture, glue) for closure

1.YV.87.LA-AY

Excision partial, skin of leg open [excisional] approach and dermatome with apposition technique (suture, glue) for closure

1.YV.87.LA-AY-A

Excision partial, skin of leg open [excisional] approach and dermatome using full-thickness autograft

1.YV.87.LA-AY-B

Excision partial, skin of leg open [excisional] approach and dermatome using split-thickness autograft

1.YV.87.LA-AY-E

Excision partial, skin of leg open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YV.87.LA-AY-F

Excision partial, skin of leg open [excisional] approach and dermatome using free flap

1.YV.87.LA-XX-A

Excision partial, skin of leg open [excisional] approach using full-thickness autograft

1.YV.87.LA-XX-B

Excision partial, skin of leg open [excisional] approach using split-thickness autograft

1.YV.87.LA-XX-E

Excision partial, skin of leg open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YV.87.LA-XX-F

Excision partial, skin of leg open [excisional] approach using free flap

1.YW.80

Repair, skin of foot

1.YW.80.JA-XX-K

Repair, skin of foot using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YW.80.JA-XX-P

Repair, skin of foot using cultured tissue

1.YW.80.LA-XX-A

Repair, skin of foot using full-thickness autograft

1.YW.80.LA-XX-B

Repair, skin of foot using split-thickness autograft

1.YW.80.LA-XX-E

Repair, skin of foot using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YW.80.LA-XX-F

Repair, skin of foot using free flap [e.g., fasciocutaneous]

1.YW.87

Excision partial, skin of foot

1.YW.87.LA-XX-A

Excision partial, skin of foot open [excisional] approach using full-thickness autograft

1.YW.87.LA-XX-B

Excision partial, skin of foot open [excisional] approach using split-thickness autograft

1.YW.87.LA-XX-E

Excision partial, skin of foot open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YZ.80

Repair, skin NEC

1.YZ.80.JA-FF

Repair, skin NEC using closure device (e.g., clip, adhesive skin closure [Steri-Strips])

1.YZ.80.JA-XX-K

Repair, skin NEC using homograft (e.g., GRAFTJACKET regenerative tissue matrix)

1.YZ.80.JA-XX-P

Repair, skin NEC using cultured tissue

1.YZ.80.LA

Repair, skin NEC using apposition technique [suture]

1.YZ.80.LA-XX-A

Repair, skin NEC using full-thickness autograft

1.YZ.80.LA-XX-B

Repair, skin NEC using split-thickness autograft

1.YZ.80.LA-XX-E

Repair, skin NEC using local flap [e.g., rotation, advancement, transposition, Z-plasty]

1.YZ.80.LA-XX-F

Repair, skin NEC using open approach and free flap [e.g., microvascular free flap]

1.YZ.87

Excision partial, skin NEC

1.YZ.87.LA

Excision partial, skin NEC open [excisional] approach with apposition technique (suture, glue) for closure

1.YZ.87.LA-AY

Excision partial, skin NEC open [excisional] approach and dermatome with apposition technique (suture, glue) for closure

1.YZ.87.LA-AY-A

Excision partial, skin NEC open [excisional] approach and dermatome using full-thickness autograft

1.YZ.87.LA-AY-B

Excision partial, skin NEC open [excisional] approach and dermatome using split-thickness autograft

1.YZ.87.LA-AY-E

Excision partial, skin NEC open [excisional] approach and dermatome using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YZ.87.LA-AY-F

Excision partial, skin NEC open [excisional] approach and dermatome using free flap

1.YZ.87.LA-XX-A

Excision partial, skin NEC open [excisional] approach using full-thickness autograft

1.YZ.87.LA-XX-B

Excision partial, skin NEC open [excisional] approach using split-thickness autograft

1.YZ.87.LA-XX-E

Excision partial, skin NEC open [excisional] approach using local flap [e.g., rotation, advancement, transposition, Z-plasty] for closure

1.YZ.87.LA-XX-F

Excision partial, skin NEC open [excisional] approach using free flap

Radiation CCI procedure codes

Local

Code

Fee code description

1.YF.27

Radiation, skin of face

1.YS.27

Radiation, skin of abdomen and trunk

1.YT.27

Radiation, skin of arm

1.YV.27

Radiation, skin of leg

1.YZ.27

Radiation, skin NEC

Regional

Code

Fee code description

1.MD.27

Radiation, lymph node(s), axillary

1.MH.27

Radiation, lymph node(s), pelvic

1.MJ.27

Radiation, lymph node(s), inguinal

Metastases

Code

Fee code description

1.AN.27

Radiation, brain

1.AW.27

Radiation, spinal cord

1.EA.27

Radiation, cranium

1.Equation 27

Radiation, soft tissue of head and neck

1.GT.27

Radiation, lung NEC

1.MF.27

Radiation, lymph node(s), intrathoracic NEC

1.MH.27

Radiation, lymph node(s), pelvic

1.PB.27

Radiation, adrenal gland

1.PC.27

Radiation, kidney

1.SC.27

Radiation, spinal vertebrae

1.SH.27

Radiation, soft tissue of the back

1.SL.27

Radiation, ribs

1.SQ.27

Radiation, pelvis

1.SZ.27

Radiation, soft tissue of the chest and abdomen

1.TX.27

Radiation, soft tissue of arm NEC

1.TZ.27

Radiation, arm NEC

1.VX.27

Radiation, soft tissue of leg

1.VZ.27

Radiation, leg NEC

1.WZ.27

Radiation, Musculoskeletal system NEC

1.YM.27

Radiation, breast

Chemotherapy DINs

DIN

Description

02241093

TEMOZOLOMIDE

02241094

TEMOZOLOMIDE

02241095

TEMOZOLOMIDE

02241096

TEMOZOLOMIDE

02312794

TEMOZOLOMIDE

02312816

TEMOZOLOMIDE

02380242

VEMURAFENIB

02395274

TEMOZOLOMIDE

02395282

TEMOZOLOMIDE

02395290

TEMOZOLOMIDE

02395312

TEMOZOLOMIDE

02409607

DABRAFENIB

02409615

DABRAFENIB

02409623

TRAMETINIB RECOMBINANT

02409658

TRAMETINIB RECOMBINANT

02441152

PEMBROLIZUMAB

Chemotherapy OHIP fee codes

Code

Fee code description

G281

D./T. PROC.INJ/INF-INTRAVEN-CHEMOTHERAPY-EA.ADD.INJ.TO G381

G345

D&T MULT.AGENTS CHEMOTHER.GREATER THAN 10 UNITS PER MET.SQ

G359

D&T SING.AGENT CHEMOTHER.(GREATER THAN 2G/M2 OR 1G/M2.)

G381

D./T. PROC. INJECT/INFUS. INTRAVENOUS CHEMOTHERAPY-1ST INJ

Inadequate surgery OHIP fee codes

Code

Fee code description

E300

EAR-EXT.-EXC-RESECT.PINNA-WITH PRIMARY CLOSURE

E301

EAR-EXT.-EXC-RESECT.PINNA-WITH LOCAL FLAP

E540

SKIN-MALIG.LESION-EXC-IN HOSP-TUMOUR FREE MARGIN ADD 25%

E542

ADD ON CODE TO SERVICES WHEN PERFORMED OUTSIDE HOSPITAL

M012

NOSE-EXC.-SEPTUM-SUBMUCOUS RESECTION INCL. SEPTOPLASTY

R018

SKIN-CURRET-ELECTRO DESIC/CRYOSURG-LOC.MALIG-FACE/NECK-1 LES

R019

SKIN-CURRET/ELECTRO DESIC/CRYOSURG-LOC.MALIG-FACE/NECK-2 LES

R020

SKIN-CURRET/ELECTRO DESIC/CRYOSURG-LOC.MALIG-FACE/NECK-3/MOR

R031

SKIN & SUBCUT.TISSUE-CURETT.& ELECTRODES.LOC MALIG.1 LESION

R032

SKIN & SUBCUT.TISSUE-CURETT.& ELECTRODES.LOC MALIG 2 LESIONS

R033

SKIN & SUBCUT.TISS.-CURET.& ELECTRO-LOC MALIG-3/MORE LESIONS

R040

SKIN-EXC/CURET + DESSICAT./CRYOSURG.INCL.BIOPSY LOCAL.MALIG.-2

R041

SKIN-EXC/CURET + DESSICAT/CRYOSURG.INCL.BIOP.LOCAL MALIG3/MORE

R048

SKIN-EXC.-LOC.MALIG.INCL.BIOPSY-FACE/NECK-1 LESION.

R049

SKIN-EXC.-LOC.MALIG.INCL.BIOPSY-FACE/NECK-2 LESIONS

R050

SKIN-EXC.-LOC.MALIG.INCL.BIOPSY-FACE/NECK-3/MORE LESIONS.

R094

SKIN-EXC-SIMPLE-MALIG.LESION-OTHER AREA-INCL.BIOPSY-ONE

R160

Pre-malignant lesions including biopsy of each lesion—face or neck—simple excision—single lesion

R161

Face or neck—simple excision—two lesions

R162

Face or neck—simple excision—three or more lesions

R163

Pre-malignant lesions including biopsy of each lesion—other areas—simple excision—single lesion

R164

Other areas—simple excision—two lesions

R165

Other areas—simple excision—three or more lesions

R993

TUMOUR-EXCISION-NOT SPECIFICALLY LISTED-I.C.

S010

LIPS-EXC.-WEDGE RESECTION & PLASTIC REPAIR

S011

LIPS-EXC.-WEDGE RESECTION VERMILLION.

S249

ANUS-EXC.-LOCAL FOR MALIGNANCY

Z080

Debridement of wound(s) and/or ulcer(s) extending into subcutaneous tissue—one

Z081

Debridement of wound(s) and/or ulcer(s) extending into subcutaneous tissue—two

Z082

Debridement of wound(s) and/or ulcer(s) extending into subcutaneous tissue—three

Z083

Debridement of wound(s) and/or ulcer(s) extending into subcutaneous tissue—four or more

Z084

Debridement of wound(s) and/or ulcer(s) extending into any of the following structures: tendon, ligament, bursa and/or bone—one

Z085

Debridement of wound(s) and/or ulcer(s) extending into any of the following structures: tendon, ligament, bursa and/or bone—two or more

Z117

SKIN.CHEM/CRYOTHERAPY MINOR SKIN LESIONS 1/MORE

Z123

SKIN-EXC.-GROUP 4-FACE/NECK-TWO LESIONS-LOC. ANAES.

Z128

SKIN-DESTRUCTION FINGER/TOENAIL PART/COMP./NAIL PLATE EXC.1

Z129

SKIN-DESTRUCTION-FINGER/TOENAIL-SIMPLE-PART/COMPL.-MULTI

Z162

SKIN-EXC-SUT.-NAEVUS-ONE.

Z163

SKIN-EXC-SUT.-NAEVUS-TWO.

Z164

SKIN-EXC-SUT.-NAEVUS-THREE/MORE.

Z165

SKIN-EXC-SUT.-NAEVUS-CONGENITAL-EXTENSIVE.

Z166

SKIN-EXC-SUT.-PLANTAR-ONE.

Z169

SKIN & SUBCUT.-PLANTAR-REMOVAL BY ELECTRO.-SINGLE LESION

Z170

SKIN & SUBCUT.-PLANTAR-REMOVAL BY ELECTRO.-TWO LESIONS

Z171

SKIN & SUBCUT.-PLANTAR-REMOVAL BY ELECTRO-THREE/MORE LESIONS

Z502

MOUTH-EXC-LESION-LESS THAN 2CM.

Z504

LIPS-EXC.-LESION

Biopsy OHIP fee codes

Code

Fee code description

E172

EYE ORBIT-EXC.-BIOPSY-ANTERIOR ROUTE

E542

ADD ON CODE TO SERVICES WHEN PERFORMED OUTSIDE HOSPITAL

Z113

INTEGUMENTARY SYST.BIOPSY(S)-ANY METHOD, SUTURES NOT USED

Z116

SURG.PROC SKIN-BIOPSY(S)ANY METHOD WHEN SUTURES USED

Z155

SKIN-INC.-BIOPSY EXTENSIVE/COMPLICATED/GEN.ANAES.-SOLE PROC

Z309

NOSE-EXC.-BIOPSY-LOC. ANAES

Z405

LYMPHATIC-NODES-EXC.-BIOPSY-CERVICAL,AXILLARY,INGUINAL

Z406

LYMPHATIC-NODES-EXC.-BIOPSY-SCALENE

Z411

Axillary or inguinal lymph node(s), unilateral

Z475

VULVA & INTROITUS-EXCISION-BIOPSY-GEN.ANAESTHETIC

Z477

VULVA & INTROITUS-EXCISION-BIOPSY-LOC.ANAESTHETIC

Z501

MOUTH-INC.-BIOPSY

Z503

LIPS-INC.-BIOPSY

Z544

ANUS-INC. BIOPSY

Z702

PENIS-EXC.-BIOPSY

Z722

VAGINA-EXC.-BIOPSY-LOCAL ANAESTHETIC-SOLE PROCEDURE

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Austin, J., Wright, F.C., Cheng, S.Y. et al. Outcomes of Immunosuppressed Patients Who Develop Melanoma: A Population-Based Propensity-Matched Cohort Study. Ann Surg Oncol 27, 2927–2948 (2020). https://doi.org/10.1245/s10434-020-08265-4

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