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Therapeutic potential of ginger bio-active compounds in gastrointestinal cancer therapy: the molecular mechanism

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A Correction to this article was published on 12 August 2022

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Abstract

The scientific literature indicates that ginger is known for its medicinal properties from ancient times. Ginger is an excellent source of bio-active compounds. It can stimulate the immune system to protect against various types of cancers. In the review, the bio-active compounds of ginger like gingerols, shogaols, paradols, terpenes, camphene, zingerone, and zingiberene and their role in ameliorating liver, pancreatic, colorectal, and gastric cancer types by inhibiting multiple pathways of carcinogenesis are discussed. Additionally, ginger compound-based nanoparticles have been discussed in terms of cancer therapeutics. Various ginger-derived nanoparticles synthesized employing technology have focused on delivering chemotherapeutic medications into specific cancer cells. Future studies should be an integrative method that uses nature-derived nanoparticles from edible plants to load and release cancer therapy into various malignant tissues, allowing for a faster recovery in people with multiple primary tumors.

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Authors and Affiliations

  1. School of Life Sciences, Jaipur National University, Jaipur, India

    Sharmistha Mathur, Shalini Pareek, Divya Shrivastava & Prakash S. Bisen

  2. School of Studies in Biotechnology, Jiwaji University, Gwalior, 474011, India

    Ravindra Verma & Prakash S. Bisen

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Mathur, S., Pareek, S., Verma, R. et al. Therapeutic potential of ginger bio-active compounds in gastrointestinal cancer therapy: the molecular mechanism. Nutrire 47, 15 (2022). https://doi.org/10.1186/s41110-022-00166-8

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