Background

Globally, aging has become an increasingly urgent issue and a significant challenge facing public healthcare [1]. China has one of the world’s largest ageing populations, the proportion of the population aged 65 or older had reached 14.2% in 2021, representing 200.6 million people, and this number is projected increase to 400 million by 2050 [2]. Inevitably, with greater longevity the number of chronic age-related diseases will increased. The existing disconnected and fragmented healthcare may fail to meet the demands of the ageing population, such as lack of care coordination and the uneven distribution of health services, resulting in enormous costs and burdens on the system [3]. It is estimated that older people will consume 75% of health care resources by 2030 [4]. How to fulfill healthy ageing has become a key public health challenge with the escalation of population aging. Quality of life (QoL) is one concept that has been identified as a critical aspect for healthy ageing and health promotion in old age [5].

QoL is a broad multidimensional construct assessing individuals’ perception of overall wellbeing and life, involving physical health, psychological state, social functioning, and environment [6]. Lower levels of QoL are strongly associated with adverse health outcomes. For example, poorer QoL in later life is significantly predictive of a higher frequency of hospitalization, reduced physical independence and psychosocial well-being level and, notably, increased socioeconomic burden and mortality amongst older adults [7]. Conversely, those negative outcomes have a deteriorate effect upon QoL, creating a vicious cycle that ultimately may result in decreased life expectancy [8]. On the other hand, ageing can be accompanied with the onset of comorbid diagnoses, disability, changes in lifestyle behavior, and the potential loss of independence, all of which lead to poorer QoL [8, 9]. Given the increase in life expectancy and the importance role of QoL in older people’s, maintaining and improving QoL at an advanced age has become an increasingly important nursing consideration.

Regarding QoL, literature has mainly focused on the influencing factors of QoL in older age, pointing to a dynamic interaction amongst these factors. Specifically, QoL can be affected in a complex manner by demographic and health characteristics, psychological states, social engagement, and living conditions [5, 10]. For instance, having multiple chronic diseases, cognitive and physical impairments, polypharmacy, and psychological morbidity may have a negative relationship with QoL [11, 12]. Whilst, independence in daily living life, engaging in physical exercise and other healthy lifestyle behaviors are positive predictors for good QoL [13]. In addition, there is a recognized link between social support and QoL in older adults, that is, the quality and quantity of an individual’ social support interactions can be positively related to both their health status and QoL [10, 14].

Recently developments in the field of positive psychology have provided new perspectives for understanding the connection between individual variation in QoL and positive aspects of human potential, strengths, and resources, commanding increasing attention [15]. Several positive psychological constructs have been identified to be beneficial in the field of healthy ageing [16, 17], including optimism, which can be defined as the tendency to expect positive outcomes across a variety of life domain [18]. Numerous studies have shown that optimism is a positively correlated with well-being and physical health in older people [19, 20]. Optimists are capable of adapting to and dealing with the negative impacts of ageing, reporting more positive affect and life satisfaction, and less negative affect [21]. Similarly, a graded and independent positive relationship has been reported between optimism and objective indicators of QoL (e.g., mortality) in older people [22, 23].

Gratitude, another relevant positive psychological trait in older people, it can be defined as “a generalized orientation toward recognizing and appreciating the positive in the world” [24]. Given the robust association between gratitude and multiple domains of physical and mental well-being, this construct may represent a relevant and meaningful process to positively affect QoL [24]. In addition, gratitude has been shown to be an important and independent contributor to bolster QoL, even in people struggling with adversity, such as chronic illness [25, 26]. Despite this, the association between gratitude and QoL in older people, particularly those residing in nursing residential care homes, has received little attention.

Previous studies have focused on the relationship between the total QoL scores of older adults and individual variables. However, these studies have mostly adopted a traditional variable-centered approach (e.g., regression analysis) [27, 28], ignoring the multidimensional features of QoL and the heterogeneity of sample and limiting the ability to precision intervene. Latent profile analysis (LPA), a person-centered modeling approach that attempts to identify and characterize unobserved subpopulations of multiple observed variables that recur among individuals, thereby classify heterogeneous samples into more meaningful subgroups [29, 30]. Importantly, this method allows for the identification of populations most in need of intervention and identifies where there is a need for intervention in different domains [31]. In recent years, LPA has been applied to examine QoL in older adulthood, confirming four distinct health-related QoL profiles (stable type, physical disability type, emotional disability type, and crisis type) using the European Quality of Life-5 Dimensions Questionnaire (EQ-5D) scale among community-dwelling older Korean adults [32]. Following a similar approach, Băjenaru et al. [33] identified three subgroups using the World Health Organization Quality of Life-Brief (WHOQOL-BREF) instrument in older Romanian patients, low and very low QoL, moderate QoL, and high QoL. Therefore, the application of LPA can give the potential to identify homogeneous QoL subgroups, allowing us to better understand patterns across older population and the differences between patterns.

The past few years have seen vigorous development of China’s institutional care model. According to the 2022 National Economic and Social Development Statistical Bulletin issued by the National Bureau of Statistics [34], China has approximately 40,000 nursing homes with 8.223 million nursing beds and 34 beds per thousand older adults. Due to the late development of China’s nursing home system, most nursing care institutions mainly focus on life care and lack professional medical and healthcare services, and these institutions cannot fully meet the healthcare needs of care home residents. Previous studies have shown that nursing home residents face a higher risk of poor QoL than community-dwelling older people because of poor health status, high level of dependency, absence of physical activities, and social isolation [35]. Applying an appropriate statistical approach to focus on assessing the QoL of older adults in these institutions is pivotal to improved patient care. However, to the best of our knowledge, no study has applied LPA to study QoL in older adults in Chinese nursing homes. More importantly, there is scant information concerning the contribution of positive psychological constructs (e.g., gratitude) to the QoL and its specific subgroups in residential care setting. Having a greater understanding of these psychological characteristics of QoL latent subgroups is crucial for developing resources in a targeted manner to improve QoL amongst older people.

The aim of this study is to classify patterns of QoL in Chinese older adults living in nursing homes using the LPA method, and determined whether sociodemographic factors (e.g., age), health-related factors (e.g., physical health status), and positive psychosocial factors (e.g., gratitude) are associated with a specific profile membership of QoL. We anticipate that the finding of this research may help to develop tailored interventions based upon identified patterns, particularly for those with poorer level of QoL, to enhance QoL in this population.

Methods

Design

This was a cross-sectional study that focused on older adults sampled from three nursing homes in Guangzhou, China that had long-term cooperative relationships with the study team.

Participants

Detailed data collection methods have been described in a previous study [36]. Briefly, two trained nursing researchers conducted in-person interviews using structured questionnaires to investigate the level of subjective well-being and positive psychosocial factors, including optimism, gratitude, and other variables in residents of nursing homes from November 2020 to January 2021. They also investigated the quality of life in those older adults. All participants were ≥ 60 years of age, had lived at least one month in a nursing home, had no cognitive impairment, and consented to participate. Participants were excluded if they had significant communication deficits or acute or end-stage medical conditions. All three nursing homes were located in urban districts of Guangzhou, were privately owned, had a similar size (more than 300 beds), and belonged to the medical-nursing combined model. Furthermore, they provided diverse types of activities, such as playing chess, singing, and dancing, to meet the daily life needs of older adults. As such, there were no significant differences between the facilities in terms of healthcare models or activity types (Supplementary Table S1). Ethical approval for this study was obtained from Guangzhou Medical University Institutional Review Board with the number of 202,042,009, after receiving information about the study the respondents and/or their legal guardians signed the written informed consent to participate in our study, the voluntary nature of the study and their data anonymity and confidentiality were strictly assured. The sample size was calculated using Kendall’s sample size estimation method, ensuring it would be 5–10 times that of the number of variables [37]; the number of variables in this study was 22 and so the sample size was estimated to be 110–220. Considering the possibility of invalid questionnaires, the sample size was expanded by 20%, for a final sample size of 132–264. In total, we enrolled 380 nursing home residents and sixteen responses were excluded due to the missing or invalid data, 354 participants were included for final analysis (response rate 93.15%).

Measurement outcomes

Demographic, health-related, and clinical characteristics of participants

Demographic information was collected from participants including age, gender, marital status, education, monthly pension, number of children and weekly visit by their children. Health-related variables included smoking(yes/no), drinking status(yes/no), number of times and the duration of physical activity within the previous seven days. Clinical characteristics included the presence of chronic diseases, medication regime, and number of hospitalizations within the previous year. In our study, the number of chronic diseases was defined as the sum of the presence of self-reported cardiovascular disease, cerebrovascular disease, respiratory system diseases, endocrine, nutritional, and metabolic diseases, cancer, and other diseases. The medication regime was assessed via one question, “Have you taken medications currently?”. If the older adult responded “yes”, the next question would be asked, “How many medications did you take?”. Polypharmacy was termed as when individual has taken five prescriptions drugs or more daily based upon the previously published study [38]. Number of hospitalizations was investigated by one question, “Have you been hospitalized in the past year?”.

Quality of life

The World Health Organization Quality of Life-Brief (WHOQOL-BREF) was used to assess individuals’ levels of QoL [6, 39]. The measurement includes 26 items, and 24 of these items are divided into the following four domains: physical health (seven items; e.g., “How well are you able to get around”), psychological health (six items; e.g., “How much do you enjoy life”), social relationships (three items; e.g., “How satisfied are you with your personal relationships”), and environmental health (eight items; e.g., “How safe do you feel in your daily life”).Two items assess the perception of overall quality of life and general health. All items are rated on a 5-point scale, and raw domain scores via a formula were converted to a scale ranging from 0 to 100, with higher scores denoting higher QoL [40]. In present study, Cronbach’s alpha was 0.94, 0.85, 0.85, 0.70 and 0.82 for the total WHOQOL-BREF scale, the physical health, psychological health, social relationships, and environmental health, respectively.

Optimism

The Life Orientation Test-Revised (LOT-R) scale was composed of 10 items, including three items to assess optimism, three items to assess pessimism, and four filler items [41, 42]. Sample item was “In uncertain times, I usually expect the best”. Participants indicated level of agreement on a 5-point scale, from 0 (strongly disagree) to 4(strongly agree); Optimism and pessimism scores were calculated by adding the corresponding three items, with a score range of 0 to 12. Total scores were summed up the optimism score and the inverted pessimism score, with a higher score suggesting greater sense of optimism. The Cronbach’s alpha coefficient for the LOT-R was 0.82.

Gratitude

The Gratitude questionnaire-six-item form (GQ-6) is a unidimensional scale with six items designed to assess the level of gratitude (e.g., “I have so much in life to be thankful for”) [43, 44]. Each item was responded to using a 7-point scale (1 = strongly disagree, 7 = strongly agree). Higher scores represented higher levels of gratitude. The scale demonstrated satisfactory reliability in current study with Cronbach’s alpha of 0.92.

Social support

The Perceived Social Support Scale (PSSS) included 12 items and was used to quantify the level of social support [45, 46]. It assessed the degree to which older adults perceive their support from family, friend, and significant others (e.g., I get the emotional help and support from my family when in need). Participants responded to the items on a 7-point scale from 1 (very strongly disagree) to 7 (very strongly agree). Higher values indicated greater sense of perceived social support. The Cronbach’s alpha coefficient in the study was 0.93.

Data analysis

Descriptive statistics and bivariate correlations were analyzed using SPSS 26.0. Mplus 8.3 software was used to conduct the LPA and identify the QoL subgroups based on the four WHOQOL-BREF domains. A series of model fit indices were used to determine the optimal number of latent subgroups, including Akaike information criterion (AIC), Bayesian information criterion (BIC), sample-size-adjusted BIC (ABIC), and the Vuong-Lo-Mendell-Rubin likelihood ratio test (VLMR-LRT), bootstrapped likelihood ratio test (BLRT) and Entropy. Lower values in the AIC, BIC and ABIC represented a better model fit. LMR and BLRT compared the model fit improvements between two neighboring models, and a significant P-value suggested that the k-class model fits the data better than the k-1-class model [47]. Entropy was used to determine the classification quality, with a value closer to 1 indicating a better separation of the classes [48]. Additionally, the posterior probability of classes was used to further validate the classifications, with a value ≥ 0.80 representing good discriminability [49]. Once the profiles were identified, each profile was named to best describe its characteristics and to differentiate it from other profiles. Next, an ANOVA was conducted to test the differences in the QoL subscales between the three classes. Subsequently, differences in demographic, clinical and psychosocial variables were analyzed using the chi-square and ANOVA tests for the QoL potential subtypes. Multinomial logistic regression analysis was conducted to explore the association between the identified QoL profiles and independent variables. A two-tailed P < 0.05 was considered as statistically significant.

Results

Descriptive statistics and correlations

A total of 354 older adults were analyzed in the study, with a mean (SD) age of 86.01(6.48) years, (range: 61–108 years). Among them, 264(74.6%) were females and 90(254%) were males. The majority were widowed (222, 62.7%) or married (118, 33.3%). Nearly half of the residents (48.6%) had an elementary school or below education; 61.3% reported having a monthly pension income of ≤ 5,000 Chinese yuan, 52.5% had 3 + children; and 79.1% of residents had child visits per week. Nearly all were non-smokers (96.9%) or non-drinkers (97.7%); 74.6% reported performing at least one type of physical activity at least seven times per week, and 69.8% reported at least one hour of each activity. In terms of clinical characteristics, the mean number of chronic diseases was 2.01 (SD 0.77; range 0–6) and 94.1% of residents reported having at least one chronic disease; 48% presented polypharmacy, and 20.3% reported hospitalizations in the past year. From the four QoL subscales, the environmental health domain had the highest mean score of 61.9(12.3) and the social relationships domain had the lowest mean score of 58.1(11.9). In terms of psychosocial variables, the mean score of optimism, gratitude, and social support were 17.3(3.2), 24.9(7.2), and 56.0(9.5), respectively. The bivariate correlations among the study variables are presented in Supplemental Table S2. QoL subscales showed small correlations with optimism, gratitude, and social support (all correlations were below 0.50).

Latent profile analysis for QoL

The model fit statistics for 1–4 latent profile models were presented in Table 1. With an increase in the number of latent profiles, the AIC, BIC, and ABIC gradually decreased, and the BLRT showed significant results in comparisons, which are all the models with k and k-1class. Therefore, these values did not suggest any latent solution. Although the 4-class model had the highest entropy, the P-value of the VLMR-LRT was 0.264, suggesting that the 4-class model was rejected. The 3-class model emerged a new class with clinically relevant patterns of item-response probabilities when compared with the 2-class solution. Moreover, classification quality, based on the average latent profile probabilities for most likely class membership, suggested that the 3-classes had a good discriminability and reliable classification: 0.918 for latent class 1; 0.925 for latent class 2; 0.924 for latent class 3. As such, the 3‐class model was chosen for the following analysis.

Table 1 Model fit indices for the compared latent profiles(n = 354)

Figure 1 illustrated the three classes. Class 1 consisted of 64 (18.1%) older adults and was characterized by the lowest QoL scores for all four subscales compared with the other group, particularly on psychological domain, and therefore was named ‘low quality of life with poor psychological health’ subgroup. Class 2(n = 163, 46.0%) was closed to the average QoL scores on each subscale and was labelled as ‘moderate quality of life’ subgroup. Class 3(n = 127, 35.9%) was characterized by a high QoL score and higher than average QoL scores across all subscales and was considered as ‘high quality of life’ subgroup.

The ANOVA and Bonferroni post-hoc tests indicated that QoL subscales scores differed in all three classes (P < 0.05), with psychological health exhibited the largest effect size (η2 = 0.749). Specifically, psychological health differentiates the QoL classes from each other the most, suggesting that it is the most important variable for the classification. Furthermore, as all dimensions of QoL differ between the classes in the same direction (i.e., those lowest in one dimension were likely to be the lowest in the other three), it supported the interpretability of the classifications by LPA (See Table 2).

Fig. 1
figure 1

QoL subscales for the latent profile classes. Note: Class1 = Low QoL with poor psychological health, Class2 = Moderate QoL, Class3 = High QoL. Whiskers indicate the standard error of the mean

Table 2 Differences of QoL subscales scores among three different latent classes

Comparison of demographic and psychosocial variables in each latent profile

Table 3 outlined the comparison of demographic and psychosocial variables in different profiles. Among these variables, gender, education, pension, weekly frequency of physical activity, average hours spent per time on physical activity, number of chronic diseases, optimism, gratitude, and social support were different among the three QoL classes (all P < 0.05). Additionally, there were no significant differences with respect to age, marital status, number of children, has child visits per week, smoking, drinking, polypharmacy, and hospitalizations in the past year among the three QoL classes (all P > 0.05).

Table 3 Profiles of QoL in demographic and psychosocial characteristics among older adults(n = 354)

Association of QoL profiles with demographic and psychosocial factors

We used multinomial logistic regression to examine the association of the QoL profiles with demographic and psychosocial factors. Only variables that were significantly associated with QoL in the univariate analysis were entered as the independent variables in the logistic regression analysis.

First, Class 1(low QoL with poor psychological health group, as the reference class) was compared with the other classes (Fig. 2). Weekly frequency of physical activity (OR = 3.88–15.47), optimism (OR = 1.32–1.55), gratitude (OR = 1.07–1.10), and social support (OR = 1.05–1.15) were associated with the increased likelihood of belonging to the moderate-to-high QoL classes. Additionally, the probability of belonging to the low QoL with poor psychological health subgroup was associated with a college degree or higher (OR = 0.29) as compared with their respective reference groups. The probability of belonging to the high QoL group was higher for the average time spent on physical activity more than 1 h (OR = 4.40) than for less than 1 h.

Second, Class 2(moderate QoL group, reference) was compared with Class3(high QoL group). Higher weekly frequency activity and longer average hours spent on activity exhibited higher odds of belonging to high QoL class (OR = 3.99; OR = 2.54). Also, the high QoL group had a high level of optimism (OR = 1.18) and social support (OR = 1.10).

Fig. 2
figure 2

Multinomial logistic regressions showing the association of demographics, optimism, gratitude, and social support with Classes 2–3, compared with Class 1 and Class 2. The black filled circle represents the odds ratio (OR) and the horizontal line represents the 95% confidence interval (CI), ***p < 0.001 **p < 0.01 *p < 0.05. Class1 = Low QoL with poor psychological health, Class2 = Moderate QoL, Class3 = High QoL.

Discussion

The current study is the first to identify the heterogeneity of QoL and examined the variables associated with the latent subtypes via the WHOQOL-BREF, using LPA in Chinese older nursing homes residents. Two main findings emerged from our study. Firstly, three distinct profiles of QoL were identified, and these were named ‘low QoL with poor psychological mental’, ‘moderate QoL’, and ‘high QoL’. Secondly, six mainly associated factors of QoL profile were determined. A high frequency of weekly physical activity, increased time spent on activity, greater levels of optimism, gratitude, and social support were found to be associated with moderate-high QoL profiles. These findings allow the identification of predictors, which may facilitate with the development of tailormade-interventions to improve QoL of older adults.

Of the three profiles identified, the largest was the moderate QoL subgroup, to which 46.0% of older adults belonged, it was characterized by a moderate level of all WHOQOL-BREF domains (e.g., physical health, psychological health, social relationships, and environmental health). The second largest profile was the high QoL subgroup, accounting for 35.9% of older adults, these participants reported the highest level of QoL. The third profile (18.1% of older adulthood) was named low QoL with poor psychological health, as it was characterized by a low level of all QoL areas, particularly for psychological aspect. These results indicated that older adults’ perceptions of QoL varied, exhibiting individual differences. Among these groups, older adults in the low QoL with poor psychological health profile require the most attention. Thus, it is imperative to develop tailored interventions specifically targeting this population group, particularly in the realm of psychological health, so as to improve their QoL and promote healthy aging. Our findings are partially consistent with one recent Romanian study on variable-centered research of QoL, showing that the existence of three distinct QoL profiles based on WHOQOL-BREF four domains in older patients. Specifically, they found 63.3% of older people classified in the moderate QoL subgroup, 28.3% in the low QoL with poor psychological health subgroup, and 8.4% in the high QoL subgroup [33]. This discrepancy with our findings may be due to differences in sample characteristics, culture, or geographical region. Additionally, our study has revealed that the importance of psychological health in classifying the QoL among older adults. Consequently, within the different subscales of QoL, psychological health emerges as a crucial aspect that needs significant attention in our study. This finding suggests a potential necessity to customize interventions based on older adults’ psychological health condition.

The higher frequency of weekly physical activity and longer average time spent on activity, increase the likelihood of belonging to the moderate-high QoL group. Physical activity is considered a vital intervention for increasing overall well-being and quality of life in older adults [13, 50], and the frequency and duration of weekly physical activities appear to be important. The WHO evidence-based guidelines for physical activity amongst older adulthood clearly stipulates that at older adults require at least 150 to 300 min of moderate-intensity, or 75 to 150 min of vigorous-intensity physical activity every week to maintain health [51]. In addition, evidence suggests that increasing physical activity to recommended levels (moderate-to-vigorous activity performed in bouts of at least 10 min) can help prevent and reduce the prevalence of non-communicable diseases among older adults [52]. Studies have demonstrated that several types of exercise such as Yoga, Qigong, and Tai Chi all generated a positive effect on QoL of older people [53]. However, the level of physical activity among nursing home residents is generally low [54], possibly due to their inadequate awareness of activity and relatively poor physical condition. Because of this, institutional-level awareness programs and the provision of fitness facilities are required to motivate nursing home residents to engage in daily physical activity. Considering that the level of physical activity that care home residents can engage in may depend on their level of mobility, targeted physical activities should be developed to offer appropriate exercises based on the capabilities of individual residents. One unanticipated finding of this study was that older people with a college degree or higher had a higher likelihood of having poor QoL. This finding seems to correlate with the different perceptions of QoL in highly educated residents, attributed to their different attitudes, expectations, and coping strategies; this educated group generally has higher expectations, may be more critical of nursing home care, may be less willing to accept their circumstances, and may feel that they have no voice in the nursing home [55]. Nursing home life may be more stressful for them and, consequently, more destructive to their sense of identity [56]. Together, these factors may have led to low satisfaction and reported QoL, indicating that more attention should be paid to highly educated individuals in care homes to find ways to improve their QoL.

In terms of the most salient findings, older adults with higher levels of optimism, gratitude, and social support had a greater chance of being in the moderate-to-high QoL classes compared to the low QoL groups. The finding is strongly supported by previous studies, which have consistently indicated that higher levels of optimism, gratitude, and social support are associated with greater levels of QoL amongst older adults [14, 22, 25]. Old age is a significant period in which many biological, psychological, and social changes take place, and various challenges are encountered, influencing QoL. Optimism and gratitude both are positive psychological traits which not only focus on or appreciate the positive aspects of life, but can also mobilize affective or cope resources to better deal with and adapt to various challenges with aging [18]. Specifically, optimism can exert a positive effect on QoL via attention, interpretation, and memory cognitive processes [57]. Moreover, optimists are less likely to develop negative emotions, and use more adaptive and active coping strategies when confronting stressful situations than pessimist, which are possible explanations of how optimism positive affects QoL [58].

Regarding gratitude, “grateful” thinking may help individuals concentrate on positive feature of one’s environment, generates positive emotion, and motivates prosocial behavior that helps to build the appropriate social resources to decrease the deleterious effects of adverse events, which is then linked with better QoL [25]. This finding also corresponds to the broaden-and-build theory that greater degree of gratitude is associated with higher QoL [59]. Social support, an important external resource, is mainly provided by family, friends, or significant others, which adds older adults’ social contacts and engagement, promoting their psychological adaptation and successful aging, thereby maintaining good QoL [60]. This finding could be explained by the social escort convoy theory model, in that, individuals are given surrounded from their social networks throughout their lives, these social relationships have a protective function for their health [61]. This finding provides further support to the social support buffer model that social support is a key “buffer” against the negative impact of aging-related stress on QoL [62]. Taken together, these findings highlight the need for establishing and fostering positive psychosocial resources to maintain better QoL among older adults in the context of population aging.

This study had some limitations. Firstly, a cross-sectional design was used, meaning that the results can only identify associations between the different constructs; Additional longitudinal research with a more rigorous study design should be conducted to explore the associations derived from the results of this study. Secondly, data were collected only from older nursing home residents living in Guangzhou; this data may not be representative of the entire elderly Chinese population, limiting the ability to generalize these results to other geographical areas. Lastly, other factors influencing QoL in older adults exist, beyond those assessed in this study; for example, some organizational factors (e.g., staff attitude and care routines in nursing homes) can significantly influence QoL among nursing home residents. These factors should be incorporated in future studies examining the QoL of older adults. Despite these limitations, this study was able to show the benefits of using LPA to identify QoL profiles and examined the role of positive psychosocial resources in influencing QoL levels among older adults living in nursing homes. The results provide new insights into the associations between psychosocial resources and QoL profiles, providing a basis for developing proactive interventions.

Conclusion

This study examined three distinct profiles of QoL among older adults living in nursing homes using LPA: ‘low QoL with poor psychological health’ class, ‘moderate QoL’ class, and ‘high QoL’ class. Within Chinese older people, we have identified that frequency of weekly physical activity, activity duration, number of chronic diseases, optimism, gratitude, and social support were associated with QoL profiles. Our findings may help staffs in nursing care homes to focus on those residents who are at elevated risk for poor QoL and provide them with targeted and actionable intervention to improve the QoL of older adults in the residential setting.