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Epoxymethylation of 2-Acyl-Substituted NH Heterocycles and Transformations of the Epoxymethylation Products

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Abstract

A new procedure has been proposed for the synthesis of previously unknown pyrrolo- and indolo-1,4-epoxy[1,4]oxazepines by epoxymethylation of 2-benzoyl-1H-pyrrole and 2-benzoyl-1H-indoles with epichlorohydrin. Some transformations of the epoxymethylation products have been studied.

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REFERENCES

  1. Fauran, C.P., Eberle, J.A., Turin, M.J., Raynaud, G.M., and Gouret, C.J., US Patent no. 3951968, 1974.

  2. Angelini, T., Fringuelli, F., Lanari, D., Pizzo, F., and Vaccaro, L., Tetrahedron Lett., 2010, vol. 51, p. 1566. https://doi.org/10.1016/j.tetlet.2010.01.055

    Article  CAS  Google Scholar 

  3. Janeliunas, D., Daskeviciene, M., Malinauskas, T., and Getautis, V., Tetrahedron, 2009, vol. 65, p. 8407. https://doi.org/10.1016/j.tet.2009.07.093

    Article  CAS  Google Scholar 

  4. MacMillan, K.S., Naidoo, J., Liang, J., Melito, L., Williams, N.S., Morlock, L., Huntington, P.J., Estill, S.J., Longgood, J., Becker, G.L., McKnight, S.L., Pieper, A.A., De Brabander, J.K., and Ready, J.M., J. Am. Chem. Soc., 2011, vol. 133, p. 1428. https://doi.org/10.1021/ja108211m

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kharaneko, A.O., Pekhtereva, T.M., and Kharaneko, O.I., Russ. J. Org. Chem., 2020, vol. 56, p. 95. https://doi.org/10.1134/S1070428020010169

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 83114, Donetsk, Ukraine

    A. O. Kharaneko, T. M. Pekhtereva & O. I. Kharaneko

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  1. A. O. Kharaneko
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  2. T. M. Pekhtereva
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  3. O. I. Kharaneko
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Correspondence to A. O. Kharaneko.

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Kharaneko, A.O., Pekhtereva, T.M. & Kharaneko, O.I. Epoxymethylation of 2-Acyl-Substituted NH Heterocycles and Transformations of the Epoxymethylation Products. Russ J Org Chem 56, 1677–1684 (2020). https://doi.org/10.1134/S1070428020100012

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  • DOI: https://doi.org/10.1134/S1070428020100012

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