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Facile Chemoselective Reduction of 3-Phenacylideneoxindoles and 2-Oxoacenaphthen-1-ylidene Ketones using the Hantzsch Ester

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Abstract

The exocyclic C=C double bond in phenacylideneoxindole and 2-oxoacenaphthen-1-ylidene ketone derivatives has been selectively reduced in good yields with a combination of the Hantzsch ester and zinc chloride in acetonitrile at ambient temperature.

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Acknowledgment

The authors are grateful to Gvk Biosciences Pvt (Hyderabad, India) and Koneru Lakshmaiah Education Foundation (KLEF), Green Fields, Vaddeswaram, Guntur for their support.

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Authors and Affiliations

  1. Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Andhrapradesh, 522502, India

    N. Murthy Gandikota, R. Sekhar Bolla & I. V. Kasi Viswanath

  2. Gvk Biosciences, Hyderabad, Telangana, 500076, India

    A. Bandyopadhyay

Authors
  1. N. Murthy Gandikota
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  2. R. Sekhar Bolla
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  3. A. Bandyopadhyay
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  4. I. V. Kasi Viswanath
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Corresponding authors

Correspondence to A. Bandyopadhyay or I. V. Kasi Viswanath.

Additional information

Russian Text © The Author(s), 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 8, pp. 1308.

Supplementary Information

Experimental details and 1H NMR, 13C NMR, HRMS, and LC-MS data for this article can be accessed at the Journal’s website.

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11178_2019_2379_MOESM1_ESM.pdf

Facile Chemoselective Reduction of 3-Phenacylideneoxindoles and 2-Oxoacenaphthen-1-ylidene Ketones using the Hantzsch Ester

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Gandikota, N.M., Bolla, R.S., Bandyopadhyay, A. et al. Facile Chemoselective Reduction of 3-Phenacylideneoxindoles and 2-Oxoacenaphthen-1-ylidene Ketones using the Hantzsch Ester. Russ J Org Chem 55, 1197–1203 (2019). https://doi.org/10.1134/S1070428019080190

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  • DOI: https://doi.org/10.1134/S1070428019080190

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