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4-alkylated 2-(2,3,5-tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,2,4-triazine-3,5-diones

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Abstract

The alkylation of 2-(2,3,5-tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)- 1,2,4-triazine-3,5-diones with benzyl halides afforded the corresponding 4-benzyl derivatives whose structure was determined by spectral methods, including X-ray analysis. Some of the synthesized compounds were tested for antibacterial and antitumor activity.

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Authors and Affiliations

  1. Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, Yerevan, 0014, Armenia

    A. A. Harutyunyan, H. A. Panosyan, R. A. Tamazyan, A. G. Aivazyan & G. G. Danagulyan

  2. Russian–Armenian (Slavic) University, ul. Ovsela Emina 123, Yerevan, 0051, Armenia

    A. A. Harutyunyan & G. G. Danagulyan

Authors
  1. A. A. Harutyunyan
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  2. H. A. Panosyan
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  3. R. A. Tamazyan
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  4. A. G. Aivazyan
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  5. G. G. Danagulyan
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Correspondence to A. A. Harutyunyan.

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Original Russian Text © A.A. Harutyunyan, H.A. Panosyan, R.A. Tamazyan, A.G. Aivazyan, G.G. Danagulyan, 2017, published in Zhurnal Organicheskoi Khimii, 2017, Vol. 53, No. 4, pp. 567–570.

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Harutyunyan, A.A., Panosyan, H.A., Tamazyan, R.A. et al. 4-alkylated 2-(2,3,5-tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,2,4-triazine-3,5-diones. Russ J Org Chem 53, 573–576 (2017). https://doi.org/10.1134/S1070428017040121

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  • DOI: https://doi.org/10.1134/S1070428017040121

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