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Regioselective alkylation of isopropylidene- and cyclohexylidenepropanedinitrile with phenacyl bromides

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Abstract

Alkylation of isopropylidene- and cyclohexylidenepropanedinitrile with phenacyl bromides gave 2,2-bis(2-aryl-2-oxoethyl)propanedinitriles. Direct alkylation of propanedinitrile with phenacyl bromides afforded only 2-(2-aryl-2-oxoethyl)propanedinitriles.

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References

  1. El-Shafei, A.K., Sultan, A.A., Soliman, A.M., and Ahmed, E.A., Synth. Commun., 1995, vol. 25. p. 3211.

    Article  CAS  Google Scholar 

  2. Dyachenko, V.D. and Litvinov, V.P., Dokl. Akad. Nauk, 1997, vol. 355, p. 62.

    CAS  Google Scholar 

  3. Abdel-Latif, F.F., Pharmazie, 1990, vol. 45. p. 283.

    CAS  Google Scholar 

  4. Dyachenko, V.D. and Litvinov, V.P., Russ. J. Org. Chem., 1998, vol. 34. p. 554.

    CAS  Google Scholar 

  5. Dyachenko, A.D., Desenko, S.M., and Dyachenko, V.D., Chem. Heterocycl. Compd., 2004, vol. 40. p. 1017.

    Article  CAS  Google Scholar 

  6. Bogdanowicz-Szwed, K., Ciechanowicz-Rutkowska, M., Carny, A., Filippini, G., Pilati, T., and Rys, B., Justus Liebigs Ann. Chem., 1994, no. 6. p. 633.

    Article  Google Scholar 

  7. Dyachenko, A.D., Desenko, S.M., Dyachenko, V.D., and Chernega, A.N., Chem. Heterocycl. Compd., 2004, vol. 40. p. 1009.

    Article  CAS  Google Scholar 

  8. Mirek, J., Adamczyk, M., and Mokrosz, M., Synthesis, 1980, p. 296.

    Google Scholar 

  9. Mirek, J., Milart, P., Z. Naturforsch., Teil B, 1986, vol. 41. p. 1471.

    Google Scholar 

  10. Miyazaki, Y., Matsunaga, S., Tang, J., Maeda, Y., Nakano, N., Philippe, R.J., Shibahara, M., Liu, W., Sato, H., Wang, L., and Nolte, R.T., Bioorg. Med. Chem. Lett., 2005, vol. 15. p. 2203.

    Article  CAS  Google Scholar 

  11. Saikia, A., Chetia, A., Bora, U., and Boruan, R.C., Synlett, 2003, p. 1506.

    Google Scholar 

  12. Dyachenko, A.D., Desenko, S.M., and Dyachenko, V.D., Vestn. Khar’k. Univ., Khim., 2002, no. 549, issue 8 (31), p. 46.

    CAS  Google Scholar 

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Correspondence to V. D. Dyachenko.

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Original Russian Text © V.D. Dyachenko, A.N. Pavlova, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 12, pp. 1728–1731.

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Dyachenko, V.D., Pavlova, A.N. Regioselective alkylation of isopropylidene- and cyclohexylidenepropanedinitrile with phenacyl bromides. Russ J Org Chem 51, 1693–1696 (2015). https://doi.org/10.1134/S1070428015120040

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  • DOI: https://doi.org/10.1134/S1070428015120040

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