Skip to main content
Log in

Synthesis of selenoureas and heterocycles based thereon

  • Review
  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

Recent data on the synthesis of various selenoureas and selenium-containing heterocycles derived therefrom have been systemized, analyzed, and generalized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Organoselenium Chemistry: Synthesis and Reactions, Wirth, T., Ed., Weinheim: Wiley-VCH, 2011.

    Google Scholar 

  2. Freudendahl, D.M., Shahzad, S.A., and Wirth, T., Eur. J. Org. Chem., 2009, p. 1649.

    Google Scholar 

  3. Braga, A.L., Lüdtke, D.S., and Vargas, F., Curr. Org. Chem., 2006, vol. 10, p. 1921.

    CAS  Google Scholar 

  4. Garud, D.R., Koketsu, M., and Ishihara, H., Molecules, 2007, vol. 12, p. 504.

    CAS  Google Scholar 

  5. Shaaban, S., Arafat, M.A., and Hamama, W.S., Arkivoc, 2014, part (i), p. 470.

    Google Scholar 

  6. Nogueira, C.W., Zeni, G., and Rocha, J.B.T., Chem. Rev., 2004, vol. 104, p. 6255.

    CAS  Google Scholar 

  7. Narajji, C., Karvekar, M.D., and Das, A.K., Indian J. Pharm. Sci., 2007, vol. 9, p. 344.

    Google Scholar 

  8. Rosa, R.M., Roesler, R., Braga, A.L., Saffi, J., and Henriques, J.A.P., Braz. J. Med. Biol. Res., 2007, vol. 40, p. 1287.

    CAS  Google Scholar 

  9. Zhao, L., Li, Z., and Wirth, T., Eur. J. Org. Chem., 2011, p. 7080.

    Google Scholar 

  10. Braga, A.L., Lüdtke, D.S., Vargas, F., and Braga, R.C., Synlett, 2006, p. 1453.

    Google Scholar 

  11. Freudendahl, D.M., Santoro, S., Shahzad, S.A., Santi, C., and Wirth, T., Angew. Chem., Int. Ed., 2009, vol. 48, p. 8409.

    CAS  Google Scholar 

  12. Zhao, L.L., Jianfeng, L., Yiquan, L.J., Wirth, T., and Li, Z., Bioorg. Med. Chem., 2012, vol. 20, p. 2558.

    CAS  Google Scholar 

  13. Guan, Q.Y., Shi, X., Shen, J.B., and Zhao, G.L., Sci. China Chem., 2013, vol. 56, p. 588.

    CAS  Google Scholar 

  14. Guo, P., Wang, Q., Liu, J., Liu, L., Zhao, P., Cao, Y., Liu, Y., Qi, C., and Liu, Y., Biol. Trace Elem. Res., 2013, vol. 154, p. 304.

    CAS  Google Scholar 

  15. Terazawa, R., Garud, D.R., Hamada, N., Fujita, Y., Itoh, T., Nozawa, Y., Nakane, K., Deguchi, T., Koketsu, M., and Ito, M., Bioorg. Med. Chem., 2010, vol. 18, p. 7001.

    CAS  Google Scholar 

  16. Plano, D., Sanmartín, C., Moreno, E., Prior, C., Calvo, A., and Palopa, J.A., Bioorg. Med. Chem. Lett. 2007, 17, 6853.

    CAS  Google Scholar 

  17. Karelia, N., Desai, D., Hengst, J.A., Amin, S., Rudrabhatla, S.V., and Yun, J., Bioorg. Med. Chem. Lett., 2010, vol. 20, p. 6816.

    CAS  Google Scholar 

  18. Chou, L.-C., Huang, L.-J., Hsu, M.-H., Fang, M.-C., Yang, J.-S., Zhuang, S.-H., Lin, H.-Y., Lee, F.-Y., Teng, C.-M., and Kuo, S.-C., Eur. J. Med. Chem., 2010, vol. 45, p. 1395.

    CAS  Google Scholar 

  19. Sharma, A.K., Sharma, A., Desai, D., Madhunapantula, S.V., Huh, S.J., Robertson, G.P., and Amin, S., J. Med. Chem., 2008, vol. 51, p. 7820.

    CAS  Google Scholar 

  20. Micke, O., Schomburg, L., Buentzel, J., Kisters, K., and Muecke, R., Molecules, 2009, vol. 14, p. 3975.

    CAS  Google Scholar 

  21. Zaharia, V., Ignat, A., Ngameni, B., Kuete, V., Moungang, M.L., Fokunang, C.N., Vasilescu, M., Palibroda, N., Cristea, C., Silaghi-Dumitrescu, L., and Ngadjui, B.T., Med. Chem. Res., 2013, vol. 22, p. 5670.

    CAS  Google Scholar 

  22. Ignat (Grozav), A., Gaina, L., Kuete, V., Silaghi-Dumitrescu, L., Efferth, T., and Zaharia, V., Molecules, 2013, vol. 18, p. 4679.

    Google Scholar 

  23. Li, D.-D., He, J., and Zeng, H.-H., Appl. Organomet. Chem., 2012, vol. 26, p. 619.

    CAS  Google Scholar 

  24. Desai, D., Madhunapantula, S.R.V., Gowdahalli, K., Sharma, A., Chandagaludoreswamy, R., El-Bayoumy, K., Robertson, G.P., and Amin, S., Bioorg. Med. Chem. Lett., 2010, vol. 20, p. 2038.

    CAS  Google Scholar 

  25. Desai, D., Salli, U., Vrana, K.E., and Amin, S., Bioorg. Med. Chem. Lett., 2010, vol. 20, p. 2044.

    CAS  Google Scholar 

  26. Das, A., Bortner, J., Desai, D., Amin, S., and El-Bayoumy, K., Chem.-Biol. Int., 2009, vol. 180, p. 158.

    CAS  Google Scholar 

  27. Bijian, K., Zhang, Z., Xu, B., Jie, S., Chen, B., Wan, S., Wu, J., Jiang, T., and Alaoui-Jamali, M.A., Eur. J. Med. Chem., 2012, vol. 48, p. 143.

    CAS  Google Scholar 

  28. Madhunapantula, S.V., Desai, D., Sharma, A., Huh, S.J., Amin, S., and Robertson, G.P., Mol. Cancer Ther., 2008, vol. 7, p. 1297.

    CAS  Google Scholar 

  29. Xing, F., Li, S., Ge, X., Wang, C., Zeng, H., Li, D., and Dong, L., Oral Oncol., 2008, vol. 44, p. 963.

    CAS  Google Scholar 

  30. Wang, L., Yang, Z., Fu, J., Yin, H., Xiong, K., Tan, Q., Jin, H., Li, J., Wang, T., Tang, W., Yin, J., Cai, G., Liu, M., Kehr, S., Becker, K., and Zeng, H., Free Radical Biol. Med., 2012, vol. 52, p. 898.

    CAS  Google Scholar 

  31. Marciniec, K., Latocha, M., Boryczka, S., and Kurczab, R., Med. Chem. Res., 2014, vol. 23, p. 3468.

    CAS  Google Scholar 

  32. Romano, B., Font, M., Encío, I., Palop, J.A., and Sanmartín, C., Eur. J. Med. Chem., 2014, vol. 83, p. 674.

    CAS  Google Scholar 

  33. Grange, R.L., Ziogas, J., North, A.J., Angus, J.A., and Schiesse, C.H., Bioorg. Med. Chem. Lett., 2008, vol. 18, p. 1241.

    CAS  Google Scholar 

  34. Radhakrishna, P.M., Sharadamma, K.C., Vagdevi, H.M., Abhilekha, P.M., Mubeen, S.R., and Nischal, K., Int. J. Chem., 2010, vol. 2, p. 149.

    CAS  Google Scholar 

  35. Tran, P.A. and Webster, T.J., Int. J. Nanomed., 2011, vol. 6, p. 1553.

    CAS  Google Scholar 

  36. Karnik, A.V., Kulkarni, A.M., Malviya, N.J., Mourya, B.R., and Jadhav, B.L., Eur. J. Med. Chem., 2008, vol. 43, p. 2615.

    CAS  Google Scholar 

  37. Sanmartín, C., Plano, D., Domínguez, E., Font, M., Calvo, A., Prior, C., Encío, I., and Palop, J.A., Molecules, 2009, vol. 14, p. 3313.

    Google Scholar 

  38. Takahashi, H., Nishina, A., Fukumoto, R., Kimura, H., Koketsu, M., and Ishihara, H., Life Sci., 2005, vol. 76, p. 2185.

    CAS  Google Scholar 

  39. Karabanovich, G., Roh, J., Smutný, T., Nemecek, J., Vicherek, P., Stolaríkova, J., Vejsova, M., Dufkova, I., Vavrova, K., Pavek, P., Klimesova, V., and Hrabalek, A., Eur. J. Med. Chem., 2014, vol. 82, p. 324.

    CAS  Google Scholar 

  40. Ryu, C.-K., Han, J.-Y., Jung, O.-J., Lee, S.-K., Lee, J.Y., and Jeong, S.H., Bioorg. Med. Chem. Lett., 2005, vol. 15, p. 679.

    CAS  Google Scholar 

  41. Zakrzewski, J. and Krawczyk, M., Bioorg. Med. Chem. Lett., 2011, vol. 21, p. 514.

    CAS  Google Scholar 

  42. Pizzo, C., Faral-Tello, P., Salinas, G., Fló, M., Robello, C., Wipf, P., and Mahler, S.G., Med. Chem. Commun., 2012, vol. 3, p. 362.

    CAS  Google Scholar 

  43. El-Shamy, I.E., Abdel-Mohsen, A.M., Al-Shehri, M.M., El-Hashash, M.A., and Al-Shamrani, K.M., Life Sci. J., 2014, vol. 11, p. 385.

    Google Scholar 

  44. Nishina, A., Kimura, H., Kozawa, K., Sommen, G.L., Nakamura, T., Heimgartner, H., Koketsu, M., and Furukawa, S., Toxicol. Appl. Pharm., 2011, vol. 257, p. 388.

    CAS  Google Scholar 

  45. Sekiguchi, A., Nishina, A., Kimura, H., Fukumoto, R., Kogami, M., Ishihara, H., and Koketsu, M., Biol. Pharm. Bull., 2006, vol. 29, p. 1404.

    CAS  Google Scholar 

  46. Takahashi, H., Nishina, A., Fukumoto, R., Kimura, H., Koketsu, M., and Ishihara, H., Life Sci., 2005, vol. 76, p. 2185.

    CAS  Google Scholar 

  47. Takahashi, H., Nishina, A., Kimura, H., Motoki, K., Koketsu, M., and Ishihara, H., Eur. J. Pharm. Sci., 2004, vol. 23, p. 207.

    CAS  Google Scholar 

  48. Battin, E.E. and Brumaghim, J.L., Cell Biochem. Biophys., 2009, vol. 55, p. 1.

    CAS  Google Scholar 

  49. Kimani, M.M., Brumaghim, J.L., and Van Dervee, D., Inorg. Chem., 2010, vol. 49, p. 9200.

    CAS  Google Scholar 

  50. Ha, S.K., Koketsu, M., Lee, K., Choi, S.Y., Park, J.-H., Ishihara, H., and Kim, S.Y., Biol. Pharm. Bull., 2005, vol. 28, p. 838.

    CAS  Google Scholar 

  51. Merino-Montiel, P., Maza, S., Martos, S., Lopez, O., Maya, I., and Fernandez-Bolanos, J.G., Eur. J. Pharm. Sci., 2013, vol. 48, p. 582.

    CAS  Google Scholar 

  52. Gerzson, M.F.B., Victoria, F.N., Radatz, C.S., de Gomes, M.G., Boeira, S.P., Jacob, R.G., Alves, D., Jesse, C.R., and Savegnago, L., Pharmacol., Biochem. Behav., 2012, vol. 102, p. 21.

    CAS  Google Scholar 

  53. Rosa, R.M., Picada, J.N., Saffi, J., and Henriques, J.A.P., Mutat. Res., 2007, vol. 628, p. 87.

    CAS  Google Scholar 

  54. Nam, K.N., Koketsu, M., and Lee, E.H., Eur. J. Pharmacol., 2008, vol. 589, p. 53.

    CAS  Google Scholar 

  55. Zhan, P., Liu, X., Fang, Z., Pannecouque, C., and De Clercq, E., Bioorg. Med. Chem., 2009, vol. 17, p. 6374.

    CAS  Google Scholar 

  56. Xiong, S., Markesbery, W.R., Shao, C., and Lovell, M.A., Antioxid. Redox Signaling, 2007, vol. 9, p. 457.

    CAS  Google Scholar 

  57. Canto, R.F.S., Barbosa, F.A.R., Nascimento, V., de Oliveira, A.S., Brighente, I.M.C., and Braga, A.L., Org. Biomol. Chem., 2014, vol. 12, p. 3470.

    CAS  Google Scholar 

  58. Mishra, B., Priyadarsini, K.I., Mohan, H., and Mugesh, G., Bioorg. Med. Chem. Lett., 2006, vol. 16, p. 5334.

    CAS  Google Scholar 

  59. Koketsu, M. and Ishihara, H., Curr. Org. Synth., 2006, vol. 3, p. 439.

    CAS  Google Scholar 

  60. Ninomiya, M., Garud, D.R., and Koketsu, M., Heterocycles, 2010, vol. 81, p. 2027.

    CAS  Google Scholar 

  61. Fernandez-Bolaños, J.G., Lopez, Ó., Ulgar, V., Maya, I., and Fuentes, J., Tetrahedron Lett., 2004, vol. 45, p. 4081.

    Google Scholar 

  62. Koketsu, M., Suzuki, N., and Ishihara, H., J. Org. Chem., 1999, vol. 64, p. 6473.

    CAS  Google Scholar 

  63. Zakrzewski, J. and Krawczyk, M., Phosphorus, Sulfur Silicon Relat. Elem., 2009, vol. 184, p. 1880.

    CAS  Google Scholar 

  64. Atanassov, P.K., Linden, A., and Heimgartner, H., Helv. Chim. Acta, 2010, vol. 93, p. 395.

    CAS  Google Scholar 

  65. Kaname, M., Minoura, M., and Sashida, H., Tetrahedron Lett., 2011, vol. 52, p. 505.

    CAS  Google Scholar 

  66. Koketsu, M., Kiyokuni, T., Sakai, T., Ando, H., and Ishihara, H., Chem. Lett., 2006, vol. 35, p. 626.

    CAS  Google Scholar 

  67. Atanassov, P.K., Linden, A., and Heimgartner, H., Helv. Chim. Acta, 2004, vol. 87, p. 1873.

    CAS  Google Scholar 

  68. López, Ó., Maza, S., Ulgar, V., Maya, I., and FernándezBolaňos, J.G., Tetrahedron, 2009, vol. 65, p. 2556.

    Google Scholar 

  69. Proshin, A.N., Serkov, I.V., and Bachurin, S.O., Dokl. Chem., 2010, vol. 430, p. 8.

    CAS  Google Scholar 

  70. Proshin, A.N., Serkov, I.V., Chemyak, A.V., and Bachurin, S.O., Dokl. Chem., 2013, vol. 451, p. 201.

    CAS  Google Scholar 

  71. Koketsu, M., Yamamura, Y., Aoki, H., and Ishihara, H., Phosphorus, Sulfur Silicon Relat. Elem., 2006, vol. 181, p. 2699.

    CAS  Google Scholar 

  72. Keil, D. and Hartmann, H., Synthesis, 2004, p. 15.

    Google Scholar 

  73. Šibor, J., Žùrek, D., Marek, R., Kutý, M., Humpa, O., Marek, J., and Pazdera, P., Collect. Czech. Chem. Commun., 1999, vol. 64, p. 1673.

    Google Scholar 

  74. Pazdera, P., Sibor, J., Marek, R., Kuty, M., and Marek, J., Molecules, 1997, vol. 2, p. 135.

    CAS  Google Scholar 

  75. Tanahashi, N. and Koketsu, M., Tetrahedron Lett., 2011, vol. 52, p. 4650.

    CAS  Google Scholar 

  76. Koketsu, M., Takakura, N., and Ishihara, H., Synth. Commun., 2002, vol. 32, p. 3075.

    CAS  Google Scholar 

  77. Koketsu, M., Fukuta, Y., and Ishihara, H., J. Org. Chem., 2002, vol. 67, p. 1008.

    CAS  Google Scholar 

  78. Koketsu, M., Fukuta, Y., and Ishihara, H., Tetrahedron Lett., 2001, vol. 42, p. 6333.

    CAS  Google Scholar 

  79. Sogabe, S., Ando, H., Koketsu, M., and Ishihara, H., Tetrahedron Lett., 2006, vol. 47, p. 6603.

    CAS  Google Scholar 

  80. Keil, D. and Hartmann, H., Phosphorus, Sulfur Silicon Relat. Elem., 1999, vol. 152, p. 169.

    CAS  Google Scholar 

  81. Sivapriya, K., Suguna, P., Banerjee, A., Saravanan, V., Rao, D.N., and Chandrasekaran, S., Bioorg. Med. Chem. Lett., 2007, vol. 17, p. 6387.

    CAS  Google Scholar 

  82. Maeda, H., Takashima, M., Sakata, K., Watanabe, T., Honda, M., and Segi, M., Tetrahedron Lett., 2011, vol. 52, p. 415.

    CAS  Google Scholar 

  83. Klayman, D.L. and Shine, R.J., J. Org. Chem., 1969, vol. 34, p. 3549.

    CAS  Google Scholar 

  84. Kantlehner, W., Hauber, M., and Vettel, M., J. Prakt. Chem., 1996, vol. 338, p. 403.

    CAS  Google Scholar 

  85. Schonberg, A., Singer, E., and Stephan, W., Chem. Ber., 1987, vol. 120, p. 1581.

    Google Scholar 

  86. Fujiwara, S., Asanuma, Y., Shin-ike, T., and Kambe, N., J. Org. Chem., 2007, vol. 72, p. 8087.

    CAS  Google Scholar 

  87. Zhou, Y. and Denk, M.K., Tetrahedron Lett., 2003, vol. 44, p. 1295.

    CAS  Google Scholar 

  88. Koketsu, M., Nada, F., Mio, T., and Ishihara, H., Heterocycles, 2003, vol. 60, p. 1211.

    CAS  Google Scholar 

  89. Sathunuru, R. and Biehl, E., Arkivoc, 2004, part (xiv), p. 51.

    Google Scholar 

  90. Rao, U.N., Sathunuru, R., and Biehl, E.R., Heterocycles, 2004, vol. 63, p. 1067.

    CAS  Google Scholar 

  91. Heimgartner, H., Zhou, Y., Atanassov, P.K., and Sommen, G.L., Phosphorus, Sulfur Silicon Relat. Elem., 2008, vol. 183, p. 840.

    CAS  Google Scholar 

  92. Zhou, Y., Linden, A., and Heimgartner, H., Helv. Chim. Acta, 2000, vol. 83, p. 1576.

    CAS  Google Scholar 

  93. Atanassov, P.K., Zhou, Y., Linden, A., and Heimgartner, H., Helv. Chim. Acta, 2002, vol. 85, p. 1102.

    CAS  Google Scholar 

  94. El-Shamy, I.E., Abdel-Mohsen, A.M., Fouda, M.M.G., Almonasy, N., Al-Deyab, S.S., and El-Hashash, M.A., Life Sci. J., 2013, vol. 10, p. 799.

    Google Scholar 

  95. Goot, H., Eriks, J.Ch., Leurs, R., and Timmerman, H., Bioorg. Med. Chem. Lett., 1994, vol. 4, p. 1913.

    Google Scholar 

  96. Archer, S. and McGarry, R., J. Heterocycl. Chem., 1982, vol. 19, p. 1245.

    CAS  Google Scholar 

  97. Hanson, R.N., J. Heterocycl. Chem., 1984, vol. 21, p. 57.

    CAS  Google Scholar 

  98. Liebscher, J. and Hartmann, H., Z. Chem., 1976, vol. 16, p. 18.

    CAS  Google Scholar 

  99. Hanson, R.N. and Davis, M.A., J. Heterocycl. Chem., 1981, vol. 18, p. 205.

    CAS  Google Scholar 

  100. Shafiee, A., Ebrahimzadeh, M.A., and Maleki, A., J. Heterocycl. Chem., 1999, vol. 36, p. 901.

    CAS  Google Scholar 

  101. Hassaneen, H.M., Farag, A.M., Algharibtt, M.S., and Shawal, A.S., Org. Prep. Proced. Int., 1988, vol. 20, p. 505.

    CAS  Google Scholar 

  102. Shafiee, A. and Lalezari, I., J. Heterocycl. Chem., 1975, vol. 12, p. 675.

    CAS  Google Scholar 

  103. Obushak, M.D., Matiychuk, V.S., Tsyalkovsky, V.M., and Voloshchuk, R.M., Phosphorus, Sulfur Silicon Relat. Elem., 2004, vol. 179, p. 107.

    CAS  Google Scholar 

  104. Potewar, T.M., Ingale, S.A., and Srinivasan, K.V., Arkivoc, 2008, part (xii), p. 117.

    Google Scholar 

  105. Narender, M., Reddy, M.S., Kumar, V.P., Srinivas, B., Sridhar, R., Nageswar, Y.V.D., and Rao, K.R., Synthesis, 2007, p. 3469.

    Google Scholar 

  106. Narender, M., Reddy, M.S., Kumar, V.P., Reddy, V.P., Nageswar, Y.V.D., and Rao, K.R., J. Org. Chem., 2007, vol. 72, p. 1849.

    CAS  Google Scholar 

  107. Madhav, J.V., Kuarm, B.S., and Rajitha, B., Synth. Commun., 2008, vol. 38, p. 3514.

    CAS  Google Scholar 

  108. Geisler, K., Pfeiffer, W.-D., Müller, C., Nobst, E., Bulka, E., and Langer, P., Synthesis, 2003, p. 1215.

    Google Scholar 

  109. Fleischhauer, J., Beckert, R., Günther, W., Kluge, S., Zahn, S., Weston, J., Berg, D., and Görls, H., Synthesis, 2007, p. 2839.

    Google Scholar 

  110. Koketsu, M., Nada, F., and Ishihara, H., Synthesis, 2002, p. 195.

    Google Scholar 

  111. Koketsu, M., Kanoh, K., Ando, H., and Ishihara, H., Heteroatom Chem., 2006, vol. 17, p. 88.

    CAS  Google Scholar 

  112. Koketsu, M., Kanoh, K., and Ishihara, H., Heterocycles, 2006, vol. 68, p. 2647.

    CAS  Google Scholar 

  113. Koketsu, M., Kanoh, K., and Ishihara, H., Heterocycles, 2006, vol. 68, p. 2145.

    CAS  Google Scholar 

  114. Kanoh, K., Ishihara, H., and Koketsu, M., Heterocycles, 2007, vol. 74, p. 1009.

    CAS  Google Scholar 

  115. Attanasi, O.A., Filippone, P., Perrulli, F.R., and Santeusanio, S., Eur. J. Org. Chem., 2002, p. 2323.

    Google Scholar 

  116. Attanasi, O.A., Filippone, P., Guidi, B., Perrulli, F.R., and Santeusanio, S., Synlett, 2001, no. 1, p. 144.

    Google Scholar 

  117. Koketsu, M., Kanoh, K., and Ishihara, H., Heterocycles, 2006, vol. 68, p. 2627.

    CAS  Google Scholar 

  118. Koketsu, M., Tanaka, H., and Ishihara, H., Chem. Lett., 2005, vol. 34, p. 1260.

    CAS  Google Scholar 

  119. Amosova, S.V., Elokhina, V.N., Nakhmanovich, A.S., Larina, L.I., Martynov, A.V., Steele, B.R., and Potapov, V.A., Tetrahedron Lett., 2008, vol. 49, p. 974.

    CAS  Google Scholar 

  120. Koketsu, M., Imagawa, M., Mio, T., and Ishihara, H., J. Heterocycl. Chem., 2005, vol. 42, p. 831.

    CAS  Google Scholar 

  121. Koketsu, M., Mio, T., and Ishihara, H., Synthesis, 2004, p. 233.

    Google Scholar 

  122. Koketsu, M., Kogami, M., Ando, H., and Ishihara, H., Synthesis, 2006, p. 31.

    Google Scholar 

  123. Koketsu, M., Taura, M., and Ishihara, H., J. Heterocycl. Chem., 2004, vol. 41, p. 783.

    CAS  Google Scholar 

  124. Kanoh, K., Ishihara, H., and Koketsu, M., Synthesis, 2007, p. 2617.

    Google Scholar 

  125. Takahashi, M., Watanabe, S., and Kasai, T., Heterocycles, 1980, vol. 14, p. 1921.

    CAS  Google Scholar 

  126. Sibor, J., Zurek, D., Humpa, O., and Pazdera, P., Molecules, 2000, vol. 5, p. 37.

    CAS  Google Scholar 

  127. Proshin, A.N., Serkov, I.V., and Bachurin, S.O., Dokl. Chem., 2012, vol. 443, p. 80.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. N. Proshin.

Additional information

Original Russian Text © I.V. Serkov, T.M. Serova, A.N. Proshin, S.O. Bachurin, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 4, pp. 471–490.

From left to right

Igor’ Serkov was born in 1957 in Kazan. In 1980 he graduated from the Kazan Institute of Chemical Technology. Candidate of chemical sciences since 1989, doctor of chemical sciences since 2011. Leading researcher at the Institute of Physiologically Active Substances, Russian Academy of Sciences. Author of more than 60 publications and more than 10 patents.

Fields of scientific interests: medicinal chemistry and chemistry of natural biologically active substances.

Tat’yana Serova was born in 1960 in Novokuibyshevsk, Kuibyshev oblast. She graduated from the Kuibyshev State University and finished post-graduate courses at the Moscow Institute of Fine Chemical Technology. Candidate of chemical sciences since 1992; senior researcher at the Institute of Physiologically Active Substances, Russian Academy of Sciences. Author of more than 60 publications.

Fields of scientific interests: chemistry of heterocyclic compounds, biological activity of organic compounds.

Aleksei Proshin was born in 1961 in Moscow. In 1984 he graduated from the Kazan Institute of Chemical Technology. Candidate of chemical sciences since 2004. Head of Special Organic Synthesis Laboratory at the Institute of Physiologically Active Substances, Russian Academy of Sciences. Author of more than 60 publications and about 10 patents.

Fields of scientific interests: organoelement and medicinal chemistry, target-oriented synthesis of potential medicinal agents.

Sergei Bachurin was born in 1953 in Lviv. In 1975 he graduated from the Faculty of Chemistry, Moscow State University. Doctor of chemical sciences since 1994, Professor since 2003, Corresponding Member of the Russian Academy of Sciences since 2003. Director of the Institute of Physiologically Active Substances, Russian Academy of Sciences. Chairman of the Moscow Chemical Society, National Russian Representative of the “Chemistry and Human Health” Departments at the IUPAC and EFMC. Author of more than 200 publications and about 40 patents.

Fields of scientific interest and scope of research activity: medicinal chemistry, target-oriented synthesis of potential medicinal agents, biological activity of organic compounds, structure-biological activity relationships, neurochemistry.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Serkov, I.V., Serova, T.M., Proshin, A.N. et al. Synthesis of selenoureas and heterocycles based thereon. Russ J Org Chem 51, 453–471 (2015). https://doi.org/10.1134/S1070428015040016

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070428015040016

Keywords

Navigation