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Selective functionalization of the primary hydroxy group in triols

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Abstract

A procedure was suggested for preparing functionally substituted 1,2-diols by O-alkylation of hydroxyalkyl-1,3-dioxacyclanes with alkyl halides, followed by acid hydrolysis. The conditions for selective cleavage of the ethers obtained were found. (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl benzoate under the conditions of acid deacetalization undergoes saponification of the ester group.

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Authors and Affiliations

  1. Ufa State Petroleum Technical University, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062, Russia

    G. Z. Raskil’dina, V. F. Valiev, R. M. Sultanova & S. S. Zlotskii

Authors
  1. G. Z. Raskil’dina
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  2. V. F. Valiev
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  3. R. M. Sultanova
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  4. S. S. Zlotskii
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Corresponding author

Correspondence to G. Z. Raskil’dina.

Additional information

Original Russian Text © G.Z. Raskil’dina, V.F. Valiev, R.M. Sultanova, S.S. Zlotskii, 2015, published in Zhurnal Prikladnoi Khimii, 2015, Vol. 88, No. 10, pp. 1414-1419.

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Raskil’dina, G.Z., Valiev, V.F., Sultanova, R.M. et al. Selective functionalization of the primary hydroxy group in triols. Russ J Appl Chem 88, 1599–1604 (2015). https://doi.org/10.1134/S1070427215100079

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  • DOI: https://doi.org/10.1134/S1070427215100079

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