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Anticancer Potential of Nature-Derived Isoquinoline Alkaloids (A Review)

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Abstract

Isoquinoline alkaloids, vastly found in nature and predominant in Papaveraceae, Berberidaceae, and Ranunculaceae plant families, possess fascinating chemical functionality and unique mechanism diversity. Isoquinoline alkaloids exhibit potent broad-spectrum anticancer activity through various mechanisms, inclusive of arrest cell cycle and induce apoptosis, representing a fertile source for discovery of novel anticancer therapeutic agents. The purpose of the present review article is to provide a comprehensive landscape of nature-derived isoquinoline alkaloids as potential anticancer agents including their mechanisms of action, covering articles published from 2018 to present.

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Authors and Affiliations

  1. Hubei Engineering Research Center for Fragrant Plants, Hubei University of Science and Technology, 437100, Xianning, China

    B.-s. Liu, K. Liu & Y.-m. Shi

  2. Xianning Research Academy of Industrial Technology of Osmanthus Fragrans, 437100, Xianning, China

    B.-s. Liu, K. Liu, J. Wang & Y.-m. Shi

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  1. B.-s. Liu
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  2. K. Liu
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  4. Y.-m. Shi
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Liu, Bs., Liu, K., Wang, J. et al. Anticancer Potential of Nature-Derived Isoquinoline Alkaloids (A Review). Russ J Gen Chem 93, 1294–1310 (2023). https://doi.org/10.1134/S1070363223050286

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  • DOI: https://doi.org/10.1134/S1070363223050286

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