Abstract
1-Alkoxycarbonylmethyl-4-heteryl-2-pyrrolidones were synthesized by alkylation of 4-heteryl-2-pyrrolidones. 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides were prepared through the reaction of N-esters with ammonia. The resulting acetamides of 2-pyrrolidones exhibit nootropic properties, antiarrhythmic and antiischemic activity.
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Original Russian Text © O.S. Vasil’eva, E.S. Ostroglyadov, N.V. Gorodnicheva, S.V. Makarenko, I.N. Tyurenkov, V.N. Perfilova, S.M. Aleksandrova, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 7, pp. 1081–1087.
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Vasil’eva, O.S., Ostroglyadov, E.S., Gorodnicheva, N.V. et al. Synthesis and Structure of 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides. Russ J Gen Chem 88, 1374–1380 (2018). https://doi.org/10.1134/S1070363218070046
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DOI: https://doi.org/10.1134/S1070363218070046