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One-Pot Synthesis of N-Substituted Alkylaminocyclohexanols by the Addition of Electrophiles Formed in situ in the System Н2О2 + HBr (HCl)

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Abstract

Highly selective one-pot synthesis of N-substituted aminocyclohexanols has been performed by hydroxyhalogenation of the corresponding cyclohexenes with electrophilic reagents formed in situ in the system Н2О2 + HHlg (Hlg = Cl, Br), with subsequent substitution of halogen atoms with amines. Some products were tested as antimicrobial additives to motor oils and cooling lubricants and showed high antibacterial and antifungal activity.

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Authors and Affiliations

  1. Mammadaliyev Institute of Petrochemical Processes, Azerbaijan National Academy of Sciences, Hojaly ave. 30, Baku, AZ 1025, Azerbaijan

    O. A. Sadygov, Kh. M. Alimardanov, Sh. I. Ismailova & N. R. Babaev

Authors
  1. O. A. Sadygov
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  2. Kh. M. Alimardanov
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  3. Sh. I. Ismailova
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  4. N. R. Babaev
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Correspondence to O. A. Sadygov.

Additional information

Original Russian Text © О.А. Sadygov, Kh.М. Alimardanov, Sh.I. Ismailova, N.R. Babaev, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 4, pp. 566–573.

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Sadygov, O.A., Alimardanov, K.M., Ismailova, S.I. et al. One-Pot Synthesis of N-Substituted Alkylaminocyclohexanols by the Addition of Electrophiles Formed in situ in the System Н2О2 + HBr (HCl). Russ J Gen Chem 88, 650–657 (2018). https://doi.org/10.1134/S1070363218040072

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  • DOI: https://doi.org/10.1134/S1070363218040072

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