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Microwave assisted selective synthesis of (E)-1-(4-Chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones and their antimicrobial activity

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Abstract

A series of new (E)-1-(4-chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones (2a–2f) have been synthesized by selective mono cyclization of 4,6-dicinnamoyl resorcinols (1a–1f) using Vilsmeier–Haack reagent under conventional heating and microwave irradiation. The structures of the synthesized compounds have been elucidated by elemental analysis, IR, 1H NMR, 13C NMR and Mass spectral data. The synthesized compounds were tested in vitro for antimicrobial activity.

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Authors and Affiliations

  1. Green and Medicinal Chemistry Laboratory, Department of Chemistry, Osmania University, Hyderabad, 500007, India

    D. Ashok, M. Sarasija, D. Shravani, B. Vijayalaxmi & K. Sudershan

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  1. D. Ashok
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  2. M. Sarasija
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  3. D. Shravani
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  4. B. Vijayalaxmi
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  5. K. Sudershan
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Correspondence to D. Ashok.

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The text was submitted by the authors in English.

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Ashok, D., Sarasija, M., Shravani, D. et al. Microwave assisted selective synthesis of (E)-1-(4-Chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones and their antimicrobial activity. Russ J Gen Chem 86, 930–933 (2016). https://doi.org/10.1134/S1070363216040290

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  • DOI: https://doi.org/10.1134/S1070363216040290

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