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Synthesis of new 4,5-substituted 4H-1,2,4-triazole-3-thiols and their sulfanyl derivatives

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Abstract

Reaction of hydrazides of 4-alkoxybenzoic acids with benzyl isothiocyanate followed by cyclization with thiosemicarbazide afforded a series of new 4,5-substituted 4H-1,2,4-triazole-3-thiols. S-Alkylation of the latter led to the formation of the corresponding 4,5-substituted sulfanyl derivatives of 4H-1,2,4-triazoles.

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References

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Correspondence to M. A. Kaldrikyan.

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Original Russian Text © M.A. Kaldrikyan, N.S. Minasyan, R.G. Melik-Ogandzhanyan, 2015, published in Zhurnal Obshchei Khimii, 2015, Vol. 85, No. 3, pp. 459–464.

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Kaldrikyan, M.A., Minasyan, N.S. & Melik-Ogandzhanyan, R.G. Synthesis of new 4,5-substituted 4H-1,2,4-triazole-3-thiols and their sulfanyl derivatives. Russ J Gen Chem 85, 622–627 (2015). https://doi.org/10.1134/S1070363215030160

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  • DOI: https://doi.org/10.1134/S1070363215030160

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