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Antiradical Activity of Extractives from Achillea millefolium L. of the Siberian Region

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Abstract—

In model reactions with a free stable 2,2-diphenyl-1-picrylhydrazyl radical, the antiradical properties of extractives of common yarrow (Achillea millefolium L.) growing in the Krasnoyarsk Territory were studied: water-alcohol extracts with an alcohol content of 20, 40 and 70% and essential oil. Whole essential oil is obtained by exhaustive hydro-steam distillation for 11 hours. In addition, separate oil fractions were obtained: the first after 20 min from the start of distillation, the second after the next 50 minutes, the third after the next 180 min, and the fourth after the next 360 min. The results of the DPPH test showed that ARA is minimal for alcohol-soluble substances and increases for aqueous-alcoholic extracts from 20.3% in the case of a 20% extract to 21.8% for a 70% aqueous-alcoholic extract. ARA of the obtained samples of essential oil surpasses the ARA values of aqueous, alcoholic and aqueous-alcoholic extracts. It was found that the APA value for 1 fraction of oil is 29.7% and increases with the transition to subsequent fractions to 54.3%. Whole Yarrow essential oil has an ARA value of 52.8%. According to the ARA value, the extractives of yarrow can be arranged in the following row: whole essential oils > 70% aqueous-alcoholic extract > 40% extract > 20% extract > aqueous extract > 96% alcoholic extract.

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Authors and Affiliations

  1. Siberian Federal University, 660049, Krasnoyarsk, Russia

    A. A. Efremov & I. D. Zykova

  2. Special Design and Technology Bureau Nauka, Federal Research Center Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences, 660036, Akademgorodok, Krasnoyarsk, Russia

    A. A. Efremov & I. D. Zykova

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  1. A. A. Efremov
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Correspondence to A. A. Efremov.

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Efremov, A.A., Zykova, I.D. Antiradical Activity of Extractives from Achillea millefolium L. of the Siberian Region. Russ J Bioorg Chem 48, 1387–1391 (2022). https://doi.org/10.1134/S1068162022070032

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  • DOI: https://doi.org/10.1134/S1068162022070032

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