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Determining the Static Dielectric Constant of Individual Hemoglobin Molecules by Electrostatic Force Microscopy

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Abstract

A technique for determination of the dielectric constant of individual hemoglobin molecules is presented. It is based on modeling the profiles of their images obtained using electrostatic force microscopy. The obtained values of the static dielectric constant are in agreement with the known literature data. The proposed method can be adapted to determine the dielectric characteristics of individual molecules of various proteins.

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Funding

The work was performed within a government assignment to the Omsk Scientific Center, Siberian Branch, Russian Academy of Sciences, within the Basic Scientific Research Program for State Academies for 2013–2020 (registration number in EGISU NIOKTR system, AAAAA17-117041210227-8).

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Correspondence to N. A. Davletkildeev.

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The authors declare that they have no conflict of interest.

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Translated by G. Dedkov

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Davletkildeev, N.A., Sokolov, D.V., Mosur, E.Y. et al. Determining the Static Dielectric Constant of Individual Hemoglobin Molecules by Electrostatic Force Microscopy. Tech. Phys. Lett. 45, 981–983 (2019). https://doi.org/10.1134/S1063785019100067

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  • DOI: https://doi.org/10.1134/S1063785019100067

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