Abstract
The immobilization of dyes (rhodamine 6G, photosens, and photoditazine) into porous spherical calcium carbonate microparticles (vaterite modification) has been performed, and the desorption of dyes in water and sodium chloride solution of physiological concentration has been investigated. Dyes were immobilized in two ways: (i) by the adsorption of fluorophore onto previously prepared calcium carbonate particles and (ii) by adding a material to the reaction mixture when forming particles. It is found that the highest degree of particle loading (12.4 wt %) is obtained when using the second way for photoditazine. Desorption of dyes occurs mainly because of the recrystallization of particles; however, the carrier can retain photodynamic preparations for a long time.
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Original Russian Text © M.A. Vantsyan, A.A. Kochetkov, I.V. Marchenko, Yu.I. Kiryukhin, B.V. Nabatov, V.V. Artemov, T.V. Bukreeva, 2015, published in Kristallografiya, 2015, Vol. 60, No. 6, pp. 968–975.
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Vantsyan, M.A., Kochetkov, A.A., Marchenko, I.V. et al. Nanostructured calcium carbonate particles as fluorophore carriers. Crystallogr. Rep. 60, 951–958 (2015). https://doi.org/10.1134/S106377451506036X
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DOI: https://doi.org/10.1134/S106377451506036X