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Neurons with different neurotransmitters in embryonic neocortical allografts in the rat sciatic nerve

  • Developmental Biology
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Abstract

Different subsets of interneurons in the Wistar rat neocortex and in neocortical transplants developing in a damaged nerve were identified by the following immunohistochemical markers: glutamate decarboxylase (GAD 67) for GABAergic nerve cells, NO-synthase (NOS) for NO-ergic neurons, choline acetyltransferase (ChAT) for cholinergic cells, and tyrosine hydroxylase for catecholaminergic structures. Twentyeight days after surgery, individual GAD 67-ir, NO-ir, ChAT-ir, and very rarely TH-ir cells were detected in the graft. It was shown that the number of GAD 67-ir neurons per unit area in the grafts was less than in the rat neocortex P20.

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  1. Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia

    E. S. Petrova

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Correspondence to E. S. Petrova.

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Original Russian Text © E.S. Petrova, 2016, published in Izvestiya Akademii Nauk, Seriya Biologicheskaya, 2016, No. 2, pp. 128–135.

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Petrova, E.S. Neurons with different neurotransmitters in embryonic neocortical allografts in the rat sciatic nerve. Biol Bull Russ Acad Sci 43, 97–103 (2016). https://doi.org/10.1134/S1062359016020059

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