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Morphological features of cellular responses to different rates of trematode Quinqueserialis quinqueserialis (Trematoda: Notocotilidae) invasion in muskrat (Ondatra zibethicus)

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Abstract

The results of investigation of leukocyte morphology and leukocyte contents of blood and caecum depending on the trematode Quinqueserialis quinqueserialis invasion rate in muskrats from natural population are given. At low trematode invasion rates, there was observed systemic activation of lymphopoiesis and neutrophil granulocytopoiesis with a decrease in the monocyte-macrophage response in caecum (trematode localization organ). At the same time, under high invasion rates, there was detected induction of T cell suppressor activity and the absence of a granulocyte response in the tissues under study. Intensification of B lymphocyte blast transformation in caecum tissues as well as the appearance of blast cells in the blood of infected muskrats was observed.

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  1. Institute of General and Experimental Biology, Siberian Branch, Russian Academy of Sciences, ul. Sakhyanova 6, Ulan-Ude, 670047, Russia

    O. E. Mazur & A. S. Fomina

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  1. O. E. Mazur
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Original Russian Text © O.E. Mazur, A.S. Fomina, 2014, published in Izvestiya Akademii Nauk, Seriya Biologicheskaya, 2014, No. 5, pp. 492–499.

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Mazur, O.E., Fomina, A.S. Morphological features of cellular responses to different rates of trematode Quinqueserialis quinqueserialis (Trematoda: Notocotilidae) invasion in muskrat (Ondatra zibethicus). Biol Bull Russ Acad Sci 41, 444–451 (2014). https://doi.org/10.1134/S1062359014050082

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