Abstract
A device is developed for automated immunochromatographic assay, designed for one-time tests at the place of occurrence of a disease. The device comprises a turntable platform for up to five strips placed simultaneously, a unit for sample collection and microdosing to a test strip, a detection unit, and a microprocessor control system. A manual, semiautomatic, or automatic operation mode may be selected. Colloidal quantum dots with a luminescence peak from the visible to near-infrared spectral region (600–800 nm) are used as fluorescent labels. A UV-LED or a laser at 365–480 nm can be used as an excitation system; the detection device is a spectrometer with an operation range of 500–800 nm, based on a CCD series of TCD1304DG sensors (Toshiba). RFID tags of samples can re read and the analysis results can be sent to an external computer. The device is made in a plastic case for carrying.
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Original Russian Text © D.V. Krylsky, A.P. Gushchin, S.A. Gushchin, S.V. Dezhurov, O.S. Morenkov, P.P. Gladyshev, A.A. Vasiliev, 2016, published in Zhurnal Analiticheskoi Khimii, 2016, Vol. 71, No. 10, pp. 1112–1117.
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Krylsky, D.V., Gushchin, A.P., Gushchin, S.A. et al. Development of a toolkit for early precision immunochromatographic diagnosis. J Anal Chem 71, 1063–1068 (2016). https://doi.org/10.1134/S1061934816100063
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DOI: https://doi.org/10.1134/S1061934816100063