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Optimization of solid phase microextraction procedure for determination of paraquat using reduction process

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Abstract

Headspace solid phase microextraction (HS-SPME) followed by gas chromatography–mass spectrometry was developed for the determination of paraquat in urine. The volatile product resulting from reduction of paraquat by sodium borohydride–nickel chloride was used for HS-SPME. The calibration curve was linear from 10–1000 ng/mL and the limit of detection was 0.1 ng/mL. The optimized methods were validated using 500 and 750 ng/mL concentrations of paraquat in the spiked urine samples. The recoveries obtained in this study were 98.2% for intra-day (n = 6) and 99.2% for inter-day (n = 6), respectively, with RSD lower than 1.1%.

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References

  1. Gil, H.W., Kang, M.S., Yang, J.O., Lee, E.Y., and Hong, S.Y., Clin. Toxicol., 2008, vol. 46, p. 515.

    Article  CAS  Google Scholar 

  2. De Almeida, R.M. and Yonamine, M., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2007, vol. 853, p. 260.

    Article  Google Scholar 

  3. Whitehead, R.D., Montesano, M.A., Jayatilaka, N.K., Buckley, B., Winnik, B., and Needham, LL., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2010, vol. 878, p. 2548.

    Article  CAS  Google Scholar 

  4. Lee, C.Y., Lee, C.H., Shih, C.C., and Liou, H.H., Biochem. Pharmacol., 2008, vol. 76, p. 1155.

    Article  CAS  Google Scholar 

  5. Mandel, J.S., Adami, H.O., and Cole, P., Regul. Toxicol. Pharmacol., 2012, vol. 62, p. 385.

    Article  CAS  Google Scholar 

  6. Purisai, M.G., McCormack, A.L., Cumine, S., Li, J., Isla, M.Z., and Di Monte, D.A., Neurobiol. Dis., 2007, vol. 25, p. 392.

    Article  CAS  Google Scholar 

  7. Ecobichon, D.J. and Klaassen, C.D., Casarett & Doull’s Toxicology: The Basic Science of Poisons, New York: McGraw-Hill, 2001, 6th ed.

    Google Scholar 

  8. McCarthy, S., Somayajulu, M., Sikorska, M., Borowy-Borowski, H., and Pandey, S., Toxicol. Appl. Pharmacol., 2004, vol. 201, p. 21.

    Article  CAS  Google Scholar 

  9. Dinis-Oliveira, R.J., Remiao, F., Carmo, H., Duarte, J.A., Navarro, A.S., and Bastos, M.L., Neurotoxicology, 2006, vol. 27, p. 1110.

    Article  CAS  Google Scholar 

  10. Shahtaheri, S.J., Mesdaghinia, A., and Stevenson, D., Iran. J. Chem. Chem. Eng., 2005, vol. 24, p. 33.

    CAS  Google Scholar 

  11. Shahtaheri, S.J., Ibrahimi, L., Golbabaei, F., and Hosseini, M., Iran. J. Public Health, 2006, vol. 35, p. 33.

    CAS  Google Scholar 

  12. Shahtaheri, S.J., Heidari, H.R., Golbabaei, F., Alimohamadi, M., and Rahimi-Froushani, A., Iran. J. Environ. Health Sci. Eng., 2006, vol. 3, p. 169.

    CAS  Google Scholar 

  13. Koohpaei, A.R., Shahtaheri, S.J., Ganjali, M.R., Rahimi-Froushani, A., and Golbabaei, F., Iran. J. Environ. Health Sci. Eng., 2008, vol. 5, p. 283.

    CAS  Google Scholar 

  14. Heidari, H.R., Shahtaheri, S.J., Golbabaei, F., Alimohamadi, M., and Rahimi-Froushani, A., Int. J. Occup. Saf. Ergon., 2008, vol. 14, p. 395.

    Article  CAS  Google Scholar 

  15. Koohpaei, A.R., Shahtaheri, S.J., Ganjali, M.R., Rahimi-Froushani, A., and Golbabaei, F., J. Hazard. Mater., 2009, vol. 170, p. 1247.

    Article  CAS  Google Scholar 

  16. Bowles, M.R., Eyles, D.W., Hampson, E.C., and Pond, S.M., Fundam. Appl. Toxicol., 1992, vol. 19, p. 375.

    Article  CAS  Google Scholar 

  17. Li, C.B., Li, X.H., Wang, Z., Jiang, C.H., and Peng, A., World J. Emerg. Med., 2011, vol. 2, p. 179.

    Article  CAS  Google Scholar 

  18. De Almeida, R.M. and Yonamine, M., Toxicol. Mech. Methods, 2010, vol. 20, p. 424.

    Article  Google Scholar 

  19. Kawase, S., Kanno, S., and Ukai, S., J. Chromatogr., 1984, vol. 283, p. 231.

    Article  CAS  Google Scholar 

  20. Wang, Z., Wang, Z., and Xing, J., J. Anal. Toxicol., 2011, vol. 35, p. 23.

    Article  CAS  Google Scholar 

  21. Hatcher, J.M., Richardson, J.R., Guillot, T.S., McCormack, A.L., Di Monte, D.A., Jones, D.P., Pennel, K.D., and Miller, G.W., Exp. Neurol., 2007, vol. 204, p. 619.

    Article  CAS  Google Scholar 

  22. Lanaro, R., Costa, J.L., Fernandes, L.C., Resende, R.R., and Tavares, M.F., J. Anal. Toxicol., 2011, vol. 35, p. 274.

    Article  CAS  Google Scholar 

  23. Nunez, O., Moyano, E., and Galceran, M.T., J. Chromatogr. A, 2002, vol. 946, p. 275.

    Article  CAS  Google Scholar 

  24. Lee, X.P., Kumazawa, T., Fujishiro, M., Hasegawa, C., Arinobu, T., Seno, H., Ishii, A., and Sato, K., J. Mass. Spectrom., 2004, vol. 39, p. 1147.

    Article  CAS  Google Scholar 

  25. Aramendia, M.A., Borau, V., Lafont, F., Marinas, A., Marinas, J.M., Moreno, J.M., Porras, J.M., and Urbano, F.J., Food Chem., 2006, vol. 97, p. 181.

    Article  CAS  Google Scholar 

  26. Pan, L. and Pawliszyn, J., Anal. Chem., 1997, vol. 69, p. 196.

    Article  CAS  Google Scholar 

  27. Beltran, J., Lopez, F.J., and Hernandez, F., J. Chromatogr. A, 2000, vol. 885, p. 389.

    Article  CAS  Google Scholar 

  28. Cai, L., Gong, S., Chen, M., and Wu, C., Anal. Chim. Acta, 2006, vol. 559, p. 89.

    Article  CAS  Google Scholar 

  29. Ghavidel, F., Shahtraheri, S.J., Khani Jazani, R., Torabbeigi, M., Rahimi Foroshani, A., and Khadem, M., Am. J. Anal. Chem., 2014, vol. 5, p. 535.

    Article  CAS  Google Scholar 

  30. Gao, L., Liu, J., Wang, C., Liu, G., Niu, X., Shua, C., and Zhu, J., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2014, vol. 944, p. 136.

    Article  CAS  Google Scholar 

  31. Kanno, S., Takekoshi, Y., Kawase, S., and Ukai, S., Chem. Pharm. Bull., 1991, vol. 39, p. 956.

    Article  CAS  Google Scholar 

  32. Posecion, N.C., Ostrea, E.M., and Bielawski, D.M., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2008, vol. 862, p. 93.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, 14155-6446, Iran

    Fateme Ghavidel

  2. Department of Occupational Health Engineering, School of Public Health, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, 14155-6446, Iran

    Seyed Jamaleddin Shahtaheri

  3. Health, Safety and Environment School, Shahid Beheshti University of Medical Sciences, P.O. Box 16858-116, Tehran, Iran

    Marzieh Torabbeigi

  4. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, 14155-6446, Iran

    Abbas Rahimi Froushani

Authors
  1. Fateme Ghavidel
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  2. Seyed Jamaleddin Shahtaheri
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  3. Marzieh Torabbeigi
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  4. Abbas Rahimi Froushani
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Correspondence to Seyed Jamaleddin Shahtaheri.

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Ghavidel, F., Shahtaheri, S.J., Torabbeigi, M. et al. Optimization of solid phase microextraction procedure for determination of paraquat using reduction process. J Anal Chem 71, 648–652 (2016). https://doi.org/10.1134/S106193481607008X

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  • DOI: https://doi.org/10.1134/S106193481607008X

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