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Modern Aspects of Surgical Neuromodulation

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Abstract

The review focuses on the modern application of the surgical neuromodulation method for different diseases and pathological conditions. The method, initially designed and applied for deep brain stimulation, is now widely used in many fields of clinical medicine, and the effect is exerted not only by electrical stimuli. The main criterion to classify a method as a variant of neuromodulation is the presence of an implantable device, which allows minimizing the action of electric, magnetic, ultrasound impulses, or pharmacological compounds, with a decrease in the incidence of adverse effects and the precision of modulation parameters. International experience of neuromodulation in the treatment of extrapyramidal hyperkinesia, drug-resistant epilepsy, and drug-resistant pain syndromes of different origin is analyzed and compared with the data obtained by the neurosurgical team from the Research Center of Neurology. Several unique authors’ inventions allowed improving the precision of electrode positioning for deep brain stimulation (microelectrode registration) and for chronic epidural stimulation in spastic syndromes.

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Authors and Affiliations

  1. Research Center of Neurology, Moscow, Russia

    A. O. Gushcha, V. M. Tyurnikov & A. A. Kashcheev

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  1. A. O. Gushcha
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  2. V. M. Tyurnikov
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  3. A. A. Kashcheev
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Correspondence to A. O. Gushcha.

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Translated by E. Sherstyuk

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Gushcha, A.O., Tyurnikov, V.M. & Kashcheev, A.A. Modern Aspects of Surgical Neuromodulation. Hum Physiol 48, 962–967 (2022). https://doi.org/10.1134/S0362119722080047

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  • DOI: https://doi.org/10.1134/S0362119722080047

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