Abstract
Vitamin D deficiency is associated with a wide range of pathologies. Low circulating 25-hydroxyvitamin D (25(OH)D) levels have been associated with obesity. The aim of the study was to assess the relationships of serum 25(OH)D with body mass index (BMI) and body composition parameters in young adults. The study included 82 young people from 18 to 20 years of age. The 25(OH)D concentration was measured in the blood plasma, and the body composition parameters were measured by bioelectrical impedance analysis. Vitamin D deficiency varying in severity was observed in 75.6% of the subjects. The median BMI was 21.0 (19.6; 22.9) kg/m2 and body fat mass, 14.9 (10.8; 18.7) kg. All subjects with vitamin D deficiency or severe vitamin D deficiency had higher BMI, body fat (BF), and percent body fat (%BF) as compared with the subjects who had 25(OH)D > 20 ng/mL. Negative associations with 25(OH)D were observed for BMI and BF. A logistic regression analysis showed that BMI affects the vitamin D availability.
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ACKNOWLEDGMENTS
We are grateful to staff of the Central Research Laboratory of the Northern State Medical University (Arkhangelsk).
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This work was supported by the Northern State Medical University (Arkhangelsk).
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the 1964 Helsinki Declaration and its later amendments and were approved by the local Ethics Committee at the Northern State Medical University (Arkhangelsk; Minutes no. 04/01-16 dated February 3, 2016). All individual participants involved in the study voluntarily provided informed consent for participation after being informed about the potential risks and benefits and nature of the study.
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Each study participant provided a voluntary written informed consent, signed by him after explaining the potential risks and benefits, as well as the nature of the upcoming study.
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Translated by T. Tkacheva
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Kostrova, G.N., Malyavskaya, S.I. & Lebedev, A.V. Associations between 25-Hydroxyvitamin D Levels and Body Composition in Young Adults. Hum Physiol 47, 652–657 (2021). https://doi.org/10.1134/S0362119721060049
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DOI: https://doi.org/10.1134/S0362119721060049