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Event-related potentials in schizotypal personality disorder and schizophrenia

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Abstract

The article analyzes event-related potentials in the Go/NoGo test of patients with schizophrenia and schizotypal personality disorder in relation to healthy subjects. Differences identified in the group of patients with schizophrenia are consistent with previous studies and indicate disruption in processes associated with different stages of visual information processing and executive functions. Specific features of brain activity in patients with schizotypal personality disorder were significantly less pronounced and presumably pointed to changes in the processes of attention redistribution and action monitoring. The results agree well with the clinical symptoms of schizophrenia and schizotypal personality disorder, so that this technique can be considered a possible additional diagnostic criterion for these disorders.

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Authors and Affiliations

  1. N.P. Bechtereva Institute of The Human Brain, Russian Academy of Sciences, St. Petersburg, Russia

    M. V. Pronina, V. A. Ponomarev, Yu. I. Poliakov, A. Yu. Mitrofanov & J. D. Kropotov

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  1. M. V. Pronina
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  2. V. A. Ponomarev
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  3. Yu. I. Poliakov
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  4. A. Yu. Mitrofanov
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  5. J. D. Kropotov
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Correspondence to M. V. Pronina.

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Original Russian Text © M.V. Pronina, V.A. Ponomarev, Yu.I. Poliakov, A.Yu. Mitrofanov, J.D. Kropotov, 2016, published in Fiziologiya Cheloveka, 2016, Vol. 42, No. 6, pp. 27–36.

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Pronina, M.V., Ponomarev, V.A., Poliakov, Y.I. et al. Event-related potentials in schizotypal personality disorder and schizophrenia. Hum Physiol 42, 606–614 (2016). https://doi.org/10.1134/S0362119716060165

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