Skip to main content
SpringerLink
Log in

Modeling of the solubility of a solid in a liquid for organic systems

  • Published:
Theoretical Foundations of Chemical Engineering Aims and scope Submit manuscript

Abstract

The solubility of a solid in a liquid for organic systems has been modeled using thermodynamic principles. The possibility of estimating average solvation and self-association parameters allows the activity coefficients calculated for the liquid phase equilibrated with the solid phase to be carried over to the solubility problem.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Serafimov, L.A., Frolkova, A.K., and Chelyuskina, T.V., Selecting extracting agents for separation of biazeotropic binary mixtures by extractive distillation, Teor. Found. Chem. Eng., 2009, vol. 43, pp. 889–898.

    Article  CAS  Google Scholar 

  2. Serafimov, L.A., Frolkova, A.K., and Bushina, D.I., Extractive distillation of binary azeotropic mixtures, Theor. Found. Chem. Eng., 2008, vol. 42, pp. 507–516.

    Article  CAS  Google Scholar 

  3. Long, B., Li, J., Zhang, R., and Wan, L., Solubility of benzoic acid in acetone, 2-propanol, acetic acid and cyclohexane: experimental measurement and thermodynamic modeling, Fluid Phase Equilib., 2010, vol. 297, pp. 113–121.

    Article  CAS  Google Scholar 

  4. Prausnitz, J.M. and Tavares, F.W., Thermodynamics of fluid-phase equilibria for standard chemical engineering operations, AIChE J., 2004, vol. 50, pp. 739–761.

    Article  CAS  Google Scholar 

  5. Mullin, J.W., Crystallization, Oxford: ButterworthHeinemann, 2001, 4th ed.

    Google Scholar 

  6. Modarresi, H., Conte, E., Abildskov, J., Gani, R., and Crafts, P., Model-based calculation of solid solubility for solvent selection-a review, Ind. Eng. Chem. Res., 2008, vol. 47, pp. 5234–5242.

    Article  CAS  Google Scholar 

  7. O’Connell, J.P., Gani, R., Mathias, P.M., Maurer, G., Olson, J.D., and Crafts, P.A., Thermodynamic property modeling for chemical process and product engineering: some perspectives, Ind. Eng. Chem. Res., 2009, vol. 48, pp. 4619–4637.

    Article  Google Scholar 

  8. Walas, S., Phase Equilibria in Chemical Engineering, London: Butterworth, 1985.

    Google Scholar 

  9. Buchowski, H., Ksiazczak, A., and Pietrzyk, S., Solvent activity along a saturation line and solubility of hydrogen-bonding solids, J. Phys. Chem., 1980, vol. 84, pp. 975–979.

    Article  CAS  Google Scholar 

  10. Long, B. and Yang, Z., Measurements of the solubilities of m-phthalic acid in acetone, ethanol and acetic ether, Fluid Phase Equilib., 2008, vol. 266, pp. 38–41.

    Article  CAS  Google Scholar 

  11. Long, B., Wang, Y., and Yang, Z., Partition behavior of benzoic acid in (water + n-dodecane) solutions at t = (293.15 and 298.15) K, J. Chem. Thermodyn., 2008, vol. 40, pp. 1565–1568.

    Article  CAS  Google Scholar 

  12. Domanska, U., Vapor-liquid-solid equilibrium of eicosanoic acid in oneand two-component solvents, Fluid Phase Equilib., 1986, vol. 26, pp. 201–220.

    Article  CAS  Google Scholar 

  13. Esina, Z.N., Korchuganova, M.R., and Murashkin, V.V., Mathematical modeling of the liquid-solid phase transition, Vestn. Tomsk. Gos. Univ. Upravl., Vychisl. Tekh. Inform., 2011, no. 3, pp. 13–23.

    Google Scholar 

  14. Esina, Z.N., Matematicheskoe modelirovanie fazovykh perekhodov v real’nykh rastvorakh (Mathematical Modeling of Phase Transitions in Real Solutions), Kemerovo: Kemerov. Gos. Univ., 2011.

    Google Scholar 

  15. Esina, Z.N., RF Inventor’s Certificate no. 2012620983, 2012.

  16. Kogan, V.B., Geterogennye ravnovesiya (Heterogeneous Equilibria), Leningrad: Khimiya, 1968.

    Google Scholar 

  17. Stephen, H. and Stephen, T., Solubilities of Inorganic and Organic Compounds, Oxford: Pergamon, 1963, vol. 1.

    Google Scholar 

  18. Yalkovsky, S.H. and He, Y., Handbook of Aqueous Solubility Data, Boca Raton, Fla.: CRC, 2003.

    Book  Google Scholar 

  19. Jouyban, A., Handbook of Solubility Data for Pharmaceuticals, Boca Raton, Fla.: CRC, 2009.

    Book  Google Scholar 

  20. Beerbower, A., Wu, P., and Martin, A., Expanded solubility parameter approach. I: Naphthalene and benzoic acid in individual solvents, J. Pharm. Sci., 2008, vol. 73, pp. 179–188.

    Article  Google Scholar 

  21. Perlovich, G.L. and Brandl-Bauer, A., Thermodynamics of solutions. I: Benzoic acid and acetylsalicylic acid as models for drug substances and the prediction of solubility, Pharm. Res., 2003, vol. 20, pp. 471–478.

    Article  CAS  Google Scholar 

  22. Jia, Q., Ma, P., Yi, S., Wang, Q., Wang, C., and Li, G., Solubilities of benzoic acid, p-methylbenzoic acid, m-methylbenzoic acid, o-methylbenzoic acid, p-hydroxybenzoic acid, and o-nitrobenzoic acid in 1-octanol, J. Chem. Eng. Data, 2008, vol. 53, pp. 1278–1282.

    Article  CAS  Google Scholar 

  23. Pires, R.F. and Franco, Jr., M.R., Solubility of benzoic acid in aqueous solutions containing ethanol or n-propanol, J. Chem. Eng. Data, 2008, vol. 53, pp. 2704–2706.

    Article  CAS  Google Scholar 

  24. Oliveira, A.C., Coelho, M.G., Pires, R.F., and Franco, M.R., Jr., Solubility of benzoic acid in mixed solvents, J. Chem. Eng. Data, 2007, vol. 52, pp. 298–300.

    Article  CAS  Google Scholar 

  25. Wang, Q., Hou, L., Cheng, Y., and Li, X., Solubilities of benzoic acid and phthalic acid in acetic acid plus water solvent mixtures, J. Chem. Eng. Data, 2007, vol. 52, pp. 936–940.

    Article  CAS  Google Scholar 

  26. Ma, P. and Xia, Q., Determination and correlation for solubility of aromatic acids in solvents, Chin. J. Chem. Eng., 2001, vol. 9, pp. 39–44.

    CAS  Google Scholar 

  27. Burger, K., Solvation, Ionic, and Complex Formation Reactions in Non-Aqueous Solvents: Experimental Methods for Their Investigation, Amsterdam: Elsevier, 1983.

    Google Scholar 

  28. Peng, C., Liu, P., and Hu, Y., Solid-liquid equilibria based on an equation of state for chain fluids, Fluid Phase Equilib., 2001, vol. 180, pp. 299–311.

    Article  CAS  Google Scholar 

  29. Gmehling, J.G., Anderson, T.F., and Prausnitz, J.M., Solid-liquid equilibria using UNIFAC, Ind. Eng. Chem. Fundam., 1978, vol. 17, pp. 269–273.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kemerovo State University, Krasnaya ul. 6, Kemerovo, 650043, Russia

    Z. N. Esina & M. R. Korchuganova

Authors
  1. Z. N. Esina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. R. Korchuganova
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Z. N. Esina.

Additional information

Original Russian Text © Z.N. Esina, M.R. Korchuganova, 2015, published in Teoreticheskie Osnovy Khimicheskoi Tekhnologii, 2015, Vol. 49, No. 3, pp. 329–338.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Esina, Z.N., Korchuganova, M.R. Modeling of the solubility of a solid in a liquid for organic systems. Theor Found Chem Eng 49, 313–321 (2015). https://doi.org/10.1134/S0040579515030021

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0040579515030021

Keywords

Search

Navigation