An Overview on Physico-Chemical Properties of Amino Acids upon Interactions with Solution Components: A Volumetric and Viscometric Approach

Abstract

In this review article a typical investigation on the partial apparent molar volume $(V_{\varnothing }^{0})$, transfer volume $(\Delta V_{\varnothing }^{0})$, Hepler’s constant ${{({{\partial }^{2}}V_{\varnothing }^{0}{\text{/}}\partial {{T}^{2}})}_{{\text{P}}}}$, Jones–Dole coefficient (${{B}_{{\text{J}}}}$), and temperature derivative of ${{B}_{{\text{J}}}}$ or B-coefficients $(\partial {{B}_{{\text{J}}}}{\text{/}}\partial T)~$ of different amino acids in various solvents at different temperatures is carried out considering the significance and usefulness of these data in understanding the solvation and various other properties of proteins. The volumetric and viscometric parameters of amino acids have been surveyed owing to the addition of co-solute into its solutions. The interpretation on physicochemical properties is done with reference to various interactions like ion–ion, ion–solvent, solute–solvent interactions, etc. The ability of amino acids as structure maker or structure breaker in the attendance of a co-solute is also discussed. At a glance from a thoroughly reviewed literature data many important PCPs are analyzed and discussed in this article. For the binary and ternary liquid mixtures the PCPs at different temperatures were reviewed. Aiming to foster the advantage and application of PCPs of amino acids in aqueous and non-aqueous phases we present an overview of significant solution properties in terms of intrinsic and extrinsic factors.