Skip to main content
SpringerLink
Log in

Online Monitoring of Adsorption onto Silica Xerogels and Aerogels from Supercritical Solutions Using Supercritical Fluid Chromatography

  • PHYSICAL METHODS OF INVESTIGATION
  • Published:
Russian Journal of Inorganic Chemistry Aims and scope Submit manuscript

Abstract

A method for measurement of low-molecular weight compounds adsorption from solutions in liquefied gases and supercritical fluids based on the online coupling of high-pressure autoclave and supercritical fluid chromatograph has been proposed and tested. This method has been shown to be applicable to determine sorption capacity and to plot isotherms for adsorption of low-molecular weight compounds from solutions in supercritical carbon dioxide onto surface of silica xerogels and aerogels. The method provides the application of xerogels and aerogels as carriers for targeted drug delivery and controlled release.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.

Similar content being viewed by others

REFERENCES

  1. A. C. Pierre and G. M. Pajonk, Chem. Rev. 102, 4243 (2002). https://doi.org/10.1021/cr0101306

    Article  CAS  Google Scholar 

  2. I. Smirnova and P. Gurikov, J. Supercrit. Fluids 134, 228 (2018). https://doi.org/10.1016/j.supflu.2017.12.037

    Article  CAS  Google Scholar 

  3. I. Smirnova and P. Gurikov, Annu. Rev. Chem. Biomol. Eng. 8, 307 (2017). https://doi.org/10.1146/annurev-chembioeng-060816-101458

    Article  Google Scholar 

  4. Z. Ulker and C. Erkey, J. Controlled Release 177, 51 (2014). https://doi.org/10.1016/j.jconrel.2013.12.033

    Article  CAS  Google Scholar 

  5. K. E. Yorov, N. A. Sipyagina, and S. A. Lermontov, et al., Russ. J. Inorg. Chem. 61, 1339 (2016). https://doi.org/10.1134/S0036023616110048

    Article  CAS  Google Scholar 

  6. S. A. Lermontov, A. E. Baranchikov, N. A. Sipyagina, et al., Russ. J. Inorg. Chem. 65, 255 (2020). https://doi.org/10.1134/S0036023620020084

    Article  CAS  Google Scholar 

  7. S. Peper and R. Dohrn, J. Supercrit. Fluids 66, 2 (2012). https://doi.org/10.1016/j.supflu.2011.09.021

    Article  CAS  Google Scholar 

  8. G. Brunner and M. Johannsen, J. Supercrit. Fluids 38, 181 (2006). https://doi.org/10.1016/j.supflu.2006.06.008

    Article  CAS  Google Scholar 

  9. G. Guiochon and A. Tarafder, J. Chromatogr., A 1218, 1037 (2011). https://doi.org/10.1016/j.chroma.2010.12.047

  10. P. Vajda and G. Guiochon, J. Chromatogr., A 1305, 293 (2013). https://doi.org/10.1016/j.chroma.2013.06.075

  11. M. Enmark, P. Forssen, J. Samuelsson, et al., J. Chromatogr., A 1312, 124 (2013). https://doi.org/10.1016/j.chroma.2013.09.007

    Article  CAS  Google Scholar 

  12. M. Enmark, J. Samuelsson, E. Forss, et al., J. Chromatogr., A 1354, 129 (2014). https://doi.org/10.1016/j.chroma.2014.05.070

    Article  CAS  Google Scholar 

  13. M. Enmark, D. Asberg, H. Leek, et al., J. Chromatogr., A 1425, 280 (2015). https://doi.org/10.1016/j.chroma.2015.11.001

    Article  CAS  Google Scholar 

  14. M. Sun, Barbero S. Ruiz, M. Johannsen, et al., J. Chromatogr., A 1588, 127 (2019). https://doi.org/10.1016/j.chroma.2018.12.053

    Article  CAS  Google Scholar 

  15. G. Caputo, I. De Marco, and E. Reverchon, J. Supercrit. Fluids 54, 243 (2010). https://doi.org/10.1016/j.supflu.2010.05.003

    Article  CAS  Google Scholar 

  16. G. Caputo, M. Scognamiglio, and I. De Marco, Chem. Eng. Res. Des. 90, 1082 (2012). https://doi.org/10.1016/j.cherd.2011.11.011

    Article  CAS  Google Scholar 

  17. N. Singh, M. Mukhopadhyay, and M. Vinjamur, J. Supercrit. Fluids 152, 104553 (2019). https://doi.org/10.1016/j.supflu.2019.104553

    Article  CAS  Google Scholar 

  18. I. Smirnova, J. Mamic, and W. Arlt, Langmuir 19, 8521 (2003). https://doi.org/10.1021/la0345587

    Article  CAS  Google Scholar 

  19. B. S. K. Gorle, I. Smirnova, M. Dragan, et al., J. Supercrit. Fluids 44, 78 (2008). https://doi.org/10.1016/j.supflu.2007.08.004

    Article  CAS  Google Scholar 

  20. B. S. K. Gorle, I. Smirnova, and W. Arlt, J. Supercrit. Fluids 52, 249 (2010). https://doi.org/10.1016/j.supflu.2010.01.006

    Article  CAS  Google Scholar 

  21. X. Hu, S. Zheng, L. Zhu, A. R. Tanyi, et al., J. Supercrit. Fluids 79, 41 (2013). https://doi.org/10.1016/j.supflu.2013.02.015

    Article  CAS  Google Scholar 

  22. D. D. Lovskaya, A. E. Lebedev, and N. V. Menshutina, J. Supercrit. Fluids 106, 115 (2015). https://doi.org/10.1016/j.supflu.2015.07.011

    Article  CAS  Google Scholar 

  23. D. Lovskaya and N. Menshutina, Materials 13, 329 (2020). https://doi.org/10.3390/ma13020329

    Article  CAS  Google Scholar 

  24. D. S. Tsiklis, Equipment for Physicochemical Studies under High and Superhigh Pressure (Khimiya, Moscow, 1976) [in Russian].

    Google Scholar 

  25. E. D. Ramsey, B. Li, W. Guo, et al., J. Chromatogr., A 1388, 141 (2015). https://doi.org/10.1016/j.chroma.2015.02.037

    Article  CAS  Google Scholar 

  26. B. Li, W. Guo, W. Song, et al., J. Supercrit. Fluids 115, 17 (2016). https://doi.org/10.1016/j.supflu.2016.04.008

    Article  CAS  Google Scholar 

  27. B. Li, W. Guo, and E. D. Ramsey, J. Supercrit. Fluids 152, 104558 (2019). https://doi.org/10.1016/j.supflu.2019.104558

    Article  CAS  Google Scholar 

  28. S. A. Lermontov, N. A. Sipyagina, A. N. Malkova, et al., Russ. J. Inorg. Chem. 59, 1392 (2014). https://doi.org/10.1134/S0036023614120134

    Article  CAS  Google Scholar 

Download references

ACKNOWLEDGMENTS

The authors thank S.Yu. Kottsov (Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences) for the measurement of specific surface area of xerogels by low-temperature nitrogen adsorption method.

Funding

This work was supported by the Russian Science Foundation (project no. 17-73-20377).

Author information

Authors and Affiliations

  1. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russia

    M. O. Kostenko, K. B. Ustinovich & O. I. Pokrovskii

  2. Chemistry Department, Moscow State University, 119991, Moscow, Russia

    M. O. Kostenko

Authors
  1. M. O. Kostenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. B. Ustinovich
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. O. I. Pokrovskii
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to O. I. Pokrovskii.

Ethics declarations

The authors declare no conflict of interest.

Additional information

Translated by I. Kudryavtsev

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kostenko, M.O., Ustinovich, K.B. & Pokrovskii, O.I. Online Monitoring of Adsorption onto Silica Xerogels and Aerogels from Supercritical Solutions Using Supercritical Fluid Chromatography. Russ. J. Inorg. Chem. 65, 1577–1584 (2020). https://doi.org/10.1134/S0036023620100125

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0036023620100125

Keywords:

Search

Navigation