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CRYSTAL STRUCTURE OF NORFLOXACINIUM AND 2,2′-BIPYRIDYL-1′-IUM 2-THIOBARBITURATES

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Abstract

Organic salts with the composition NfH2(Htba)·6H2O (I) and BipyH(Htba)·2H2O (II) (Н2tba is 2-thiobarbituric acid, NfH is norfloxacin and Bipy is 2,2′-dipyridyl) are prepared. Their structures are determined by XRD (CCDC cif-file No. 1967494-1967495). Crystals I are triclinic: a = 11.8821(4) Å, b = 11.9959(5) Å, c = 12.0038(4) Å, α = 119.835(1)°, β = 107.691(1)°, γ = 95.237(1)°, V = 1351.80(9) Å3, space group P-1, Z = 2. Crystals II are monoclinic: a = 7.9587(2) Å, b = 19.6272(4) Å, c = 10.1118(2) Å, β = 98.118(1)°, V = 1563.71(6) Å3, space group P21/n, Z = 4. The structures are stabilized by numerous hydrogen bonds and π–π interactions involving Нtba−, \(\text{NfH}_{2}^{+}\), and BipyH+ ions. Thermal decomposition of these compounds in air includes dehydration and oxidative degradation stages.

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Funding

The reported study was funded by RFBR, project number 19-52-80003.

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Authors and Affiliations

  1. Siberian Federal University, Krasnoyarsk, Russia

    N. N. Golovnev, M. S. Molokeev & M. K. Lesnikov

  2. Kirensky Institute of Physics, Federal Research Center KSC, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russia

    M. S. Molokeev

  3. Far Eastern State Transport University, Khabarovsk, Russia

    M. S. Molokeev

  4. Favorsky Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk, Russia

    I. V. Sterkhova

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  1. N. N. Golovnev
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  2. M. S. Molokeev
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Correspondence to N. N. Golovnev.

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Golovnev, N.N., Molokeev, M.S., Sterkhova, I.V. et al. CRYSTAL STRUCTURE OF NORFLOXACINIUM AND 2,2′-BIPYRIDYL-1′-IUM 2-THIOBARBITURATES. J Struct Chem 61, 1639–1647 (2020). https://doi.org/10.1134/S0022476620100170

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