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TWO Co(II) AND Zn(II) COORDINATION POLYMERS: STRUCTURAL CHARACTERIZATION AND ANTICANCER ACTIVITY AGAINST NASOPHARYNGEAL CARCINOMA

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Abstract

By employing a mixed-ligand strategy, two new coordination polymers with the chemical formulae [Co(4-bptzh)(1,3-BDC)] (1) and [Zn(4-bptzp)(1,3-BDC)]n (2) are hydrothermally synthesized using two flexible bis(pyridyl-tetrazole) ligands (4-bptzh = 1,4-bis(5-(4-pyridyl)tetrazolyl)hexane, 4-bptzp = 1,4-bis(5-(4-pyridyl)tetrazolyl)propane) and 1,3-benzenedicarboxylic acid (1,3-H2BDC). Both complexes are characterized by single crystal X-ray diffraction along with the elemental analysis. Furthermore, the inhibitory effect of compounds 1 and 2 against CNE-1 nasopharyngeal cancer cells are evaluated in vitro. Firstly, the antiproliferation activity of compounds 1 and 2 against cancer cells is assessed by the CCK-8 assay. Then, the cancer cell apoptosis is measured with the Annexin V-FITC/PI apoptosis assay by flow cytometry.

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REFERENCES

  1. Y. F. Hou, B. Liu, K. F. Yue, C. S. Zhou, Y. M. Wang, N. Yan, and Y. Y. Wang. CrystEngComm, 2014, 16, 9560.

  2. S. Feuillastre, M. Pauton, L. Gao, A. Desmarchelier, A. J. Riives, D. Prim, D. Tondelier, B. Geffroy, G. Muller, G. Clavier, and G. Pieters. J. Am. Chem. Soc., 2016, 138, 3990.

  3. T. Kajiwara, M. Fujii, M. Tsujimoto, K. Kobayashi, M. Higuchi, K. Tanaka, and S. Kitagawa. Angew. Chem., Int. Ed., 2016, 55, 2697.

  4. P. Li, N. A. Vermeulen, X. Gong, C. D. Malliakas, J. F. Stoddart, J. T. Hupp, and O. K. Farha. Angew. Chem., Int. Ed., 2016, 55, 10358.

  5. J. Duan, W. Jin, and R. Krishna. Inorg. Chem., 2015, 54, 4279.

  6. J. Duan, M. Higuchi, J. Zheng, S. Noro, I. Y. Chang, K. Hyeon-Deuk, S. Mathew, S. Kusaka, E. Sivaniah, R. Matsuda, S. Sakaki, and S. Kitagawa. J. Am. Chem. Soc., 2017, 139, 11576.

  7. Q. Gao, J. Xu, D. Cao, Z. Chang, and X. H. Bu. Angew. Chem., Int. Ed., 2016, 55, 15027.

  8. R. An, H. Zhao, H. M. Hu, X. Wang, M. L. Yang, and G. Xue. Inorg. Chem., 2016, 55, 871.

  9. X. L. Wang, J. Zhao, H. Y. Lin, G. C. Liu, and X. Wang. Polyhedron, 2018, 145, 101.

  10. B. Wu, W. H. Zhang, Z. G. Ren, and J. P. Lang. Chem. Commun., 2015, 51, 14893.

  11. Y. Xu, F. Ding, D. Liu, P. P. Yang, and L. L. Zhu. J. Mol. Struct., 2018, 1155, 72.

  12. M. Rancan and L. Armelao. Chem. Commun., 2015, 51, 12947.

  13. S. W. Sun and G. F. Wang. J. Struct. Chem., 2019, 60(3), 466.

  14. G. F. Wang and S. W. Sun. J. Struct. Chem., 2019, 60(1), 131.

  15. D. W. Wang, B. Yang, N. Zhao, Z. J. Shi, Y. Wang, and S. L. Yang. J. Struct. Chem., 2018, 59, 1918.

  16. C. Zhang and J. Wang. J. Struct. Chem., 2019, 60, 106.

  17. G. F. Wang and S. W. Sun. J. Struct. Chem., 2018, 59, 725.

  18. R. Haldar, R. Matsuda, S. Kitagawa, S. J. George, and T. K. Maji. Angew. Chem., Int. Ed., 2014, 53, 11772.

  19. L. N. Zheng, F. H. Wei, H. M. Hu, C. Bai, X. L. Yang, X. Wang, and G. Xue. Polyhedron, 2019, 161, 47.

  20. X. G. Hu, X. Li, and S. I. Yang. Chem. Commun., 2015, 51, 10636.

  21. V. A. Blatov, A. P. Shevchenko, and D. M. Proserpio. Cryst. Growth Des., 2014, 14, 3576.

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Authors and Affiliations

  1. Otolaryngology and Maxillofacial Surgery, People′s Hospital of Wuwei City, Wuwei, Gansu, P.R. China

    Z. -X. He, Y. -F. Dong, H. -G. Liu & S. -D. Sun

  2. Integrated TCM and Western Medicine Department, People′s Hospital of Wuwei City, Wuwei, Gansu, P.R. China

    Z. -H. Zhang

  3. E.N.T. Department, People′s Hospital of Wuwei City, Wuwei, Gansu, P.R. China

    S. -Z. Wang

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  1. Z. -X. He
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  2. Z. -H. Zhang
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  3. Y. -F. Dong
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  4. H. -G. Liu
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  5. S. -D. Sun
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Correspondence to S. -Z. Wang.

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He, Z.X., Zhang, Z.H., Dong, Y.F. et al. TWO Co(II) AND Zn(II) COORDINATION POLYMERS: STRUCTURAL CHARACTERIZATION AND ANTICANCER ACTIVITY AGAINST NASOPHARYNGEAL CARCINOMA. J Struct Chem 61, 1468–1474 (2020). https://doi.org/10.1134/S0022476620090152

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