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Synthesis and Structural Characterization of a Monomeric Mixed Ligand Copper(II) Complex Involving N,N,N′,N′-Tetramethylethylenediamine and Mefenamate

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An Erratum to this article was published on 01 September 2019

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Abstract

A monomeric ternary complex [Cu(tmen)(mef)2] (1) (where mef = mefenamate anion (C15H15NO21−, tmen = N,N,N′,N′-tetramethylethylenediamine) is prepared by the reaction of CuCl2·2H2O, mefenamic acid (mefH = 2-(2,3-dimethylphenyl)aminobenzoic acid), and N,N,N′,N′-tetramethylethylenediamine (tmen) in the presence of sodium hydroxide. Complex 1 is characterized by the elemental combustion analysis, UV-visible and FT–IR spectroscopy, thermal analysis, and single crystal X-ray diffraction. From the crystal structure of complex 1, it is evident that each copper(II) ion is six-coordinate and is bonded to chelating tmen, and four O atoms of two mef anions (mef1–). In the crystal, the intramolecular hydrogen bonding exists between the H atom of the –NH group of mef and the O atom of one of the coordinated carboxylate O atoms, belonging to the same mef ligand. Complex 1 is tested for antibacterial properties against four strains, including Staphylococcus aureus, Bacillus spizizenii, Escherichia coli, and Klebsiella pneumonia. The complex shows a biological activity against Staphylococcus aureus and Bacillus spizizenii.

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Change history

  • 05 October 2019

    In the original article there was a mistake in the information of the corresponding author. The correct spelling of the names of the authors and their order is: S. S. Batool<Superscript>1,2*</Superscript>, S. R. Gilani<Superscript>1</Superscript>, S. S. Zainab<Superscript>2</Superscript>, M. N. Tahir<Superscript>3</Superscript>, W. T. A. Harrison<Superscript>4</Superscript>, Q. Syed<Superscript>5</Superscript>, and S. Mazhar<Superscript>5</Superscript>

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Acknowledgements

The authors are thankful for the financial support for this research work from the Higher Education Commission, Islamabad, Pakistan.

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Engineering and Technology, Lahore, Pakistan

    S. S. Batool & S. R. Gilani

  2. Department of Chemistry, Govt. Post Graduate Islamia college (w), Lahore, Pakistan

    S. S. Batool & S. S. Zainab

  3. Department of Physics, Sargodha University, Sargodha, Pakistan

    M. N. Tahir

  4. Department of Chemistry, University of Aberdeen, Aberdeen, Scotland

    W. T. A. Harrison

  5. Pakistan Council of Scientific and Industrial Research (PCSIR) Laboratories Complex, Lahore, Pakistan

    Q. Syed & S. Mazhar

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  1. S. S. Batool
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Correspondence to Q. Syed.

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Text © The Author(s), 2019, published in Zhurnal Strukturnoi Khimii, 2019, Vol. 60, No. 7, pp. 1203-1211.

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10947_2019_1235_MOESM1_ESM.pdf

Supplementary Materials to: Synthesis and Structural Characterization of a Monomeric Mixed Ligand Copper(II) Complex Involving N,N,N′,N′-Tetramethylethylenediamine and Mefenamate

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Batool, S.S., Gilani, S.R., Zainab, S.S. et al. Synthesis and Structural Characterization of a Monomeric Mixed Ligand Copper(II) Complex Involving N,N,N′,N′-Tetramethylethylenediamine and Mefenamate. J Struct Chem 60, 1156–1165 (2019). https://doi.org/10.1134/S0022476619070187

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