Abstract
This review summarizes the results of recent studies in which the role of selenium has been addressed by investigating the functions and biochemical properties of mammalian selenocysteine-containing proteins and their involvement in maintaining the normal function of the male reproductive system. Selenium is an essential trace element; its deficiency leads to serious diseases, including male infertility disorders, prostate cancer, testicular cancer, etc. A total of 25 selenocysteine-containing proteins are known now, and almost half of them occur in the testis, highlighting the significance of the issue.
Similar content being viewed by others
References
L. A. Wessjohann, A. Schneider, M. Abbas, and W. Brandt, J. Biol. Chem. 388, 997 (2007).
E. S. Arnér, Exp. Cell Res. 316, 1296 (2010).
C. Jacob, G. I. Giles, N. M. Giles, and H. Sies, J. Angew. Chem. Int. Ed. Engl. 42, 4742 (2003).
L. Johansson, G. Gafvelin, and E. S. Arnér, Biochim. Biophys. Acta 1726, 1 (2005).
M. Wada, S.-I. Nobuki, Y. Tenkyuu, et al., J. Organomet. Chem. 580, 282 (1999).
J. C. Pleasants, W. Guo, and D. L. Rabenstein, J. Am. Chem. Soc. 111, 6553 (1989).
L. Flohe, W. A. Gunzler, and H. H. Schock, FEBS Lett. 32, 132 (1973).
J. T. Rotruck, A. L. Pope, H. E. Ganther, et al., Science 179, 588 (1973).
H. Puzanowska-Tarasiewicz, L. Kuz’micka, and M. Tarasiewicz, Pol. Merkur. Lekarski 27, 249 (2009).
V. N. Gladyshev, K. T. Jeang, and T. C. Stadtman, Proc. Natl. Acad. Sci. USA. 93, 6146 (1996).
T. Tamura and T. C. Stadtman, Proc. Natl. Acad. Sci. USA. 93, 1006 (1996).
S. Gromer, J. Wissing, D. Behne, et al., J. Biochem. 332, 591 (1998).
G. V. Kryukov, S. Castellano, S. V. Novoselov, et al., Science 300, 1439 (2003).
K. Schwarz and C. M. Foltz, J. Am. Chem. Soc. 79, 3292 (1957).
R. Shalgi, J. Seligman, and N. S. Kosower, Biol. Reprod. 40, 1037 (1989).
I. Rosenfeld, Wyoming Agric. Exp. Sta. Bull. 414, 64 (1964).
D. G. Brown and R. F. Burk, J. Nutr. 103, 102 (1973).
L. Flohe, Biol. Chem. 388, 987 (2007).
H. D. Vlajinac, J. M. Marinkovic, M. D. Ilic, and N. I. Kocev, Eur. J. Cancer 33, 101 (1997).
M. Heinonen, A. Leppävuori, and S. Pyörälä, Anim. Reprod. Sci. 11, 235 (1998).
M. Etminan, J. M. FitzGerald, M. Gleave, and K. Chambers, Cancer Causes Control 16, 1125 (2005).
M. A. Nelson, M. Reid, A. J. Duffield-Lillico, and J. R. Marshall, Urol. Clin. North. Am. 29, 67 (2002).
D. L. McCormick, K. V. Rao, W. D. Johnson, et al., Cancer Prev. Res. (Phila.) 3, 381 (2010).
R. A. Sunde, J. Annu.Rev. Nutr. 10, 451 (1990).
I. H. Waschulewski and R. A. Sunde, J. Nutr. 118, 367 (1988).
J. R. Arthur, Cell Moll. Life Sci. 57, 1825 (2000).
F. F. Chu, J. H. Doroshow, and R. S. Esworthy, J. Biol. Chem. 268, 2571 (1993).
K. Takahashi, M. Akasaka, Y. Yamamoto, et al., J. Biochem. 108, 145 (1990).
J. Y. Choi, M. L. Neuhouser, M. Barnett, et al., Cancer Epidemiol. Biomarkers Prev. 16, 1115 (2007).
Z. Arsova-Sarafinovska, N. Matevska, A. Eken, et al., Int. Urol. Nephrol. 41, 63 (2009).
F. F. Chu, R. S. Esworthy, and J. H. Doroshow, Free Radic. Biol. Med. 36, 1481 (2004).
B. L. Emmink, J. Laoukili, A. P. Kipp, et al., Cancer Res. 74, 6717 (2014).
S. Yoshimura, K. Watanabe, H. Suemizu, et al., J. Biochem. 109, 918 (1991).
C. Schmutzler, B. Mentrup, L. Schomburg, et al., J. Biol. Chem. 388, 1053 (2007).
J. K. Christman, Oncogene 21, 5483 (2002).
R. Brigelius-Flohé, J. Biol. Chem. 387, 1329 (2006).
L. C. Clark, G. F. Combs, B. W. Turnbull, et al., J. Am. Med. Assoc. 276, 1957 (1996).
M. Maiorino, J. B. Wissing, R. Brigelius-Flohé, et al., FASEB J. 12, 1359 (1998).
S. Y. Nam, M. Fujisawa, J. S. Kim, et al., Biol. Reprod. 58, 1272 (1998).
F. Bauche, B. Fouchard, and B. Jégou, FEBS Lett. 349, 392 (1994).
R. Shalgi, J. Seligman, and N. S. Kosower, Biol. Reprod. 40, 1037 (1989).
H. Pfeifer, M. Conrad, D. Roethlein, et al., FASEB J. 15, 1236 (2001).
T. Pushpa Rekha, L. M. Burdsal, G. M. Chilsom, and D. M. Driscoll, J. Biol. Chem. 270, 26993 (1985).
A. Roveri, F. Ursini, L. Flohe, and M. Maiorino, Biofactors 14, 213 (2001).
F. Ursini, M. Maiorino, R. Brigelius-Flohe, et al., Methods Enzymol. 252, 38. (1995).
F. Ursini, S. Heim, M. Kiess, et al., Science 277, 1393 (1999).
M. Maiorino, A. Roveri, L. Benazzi, et al., J. Biol. Chem. 280, 38395 (2005).
M. Schneider, H. Förster, A. Boersma, et al., FASEB J. 23, 3233 (2009).
E. S. Arnér and A. Holmgren, Eur. J. Biochem. 267, 6102 (2000).
J. Lu and A. Holmgren, Free Radic. Biol. Med. 66, 75 (2014).
E. S. Arnér, Biochim. Biophys. Acta 1790, 495 (2009).
A. K. Rundlof and E. S. Arnér, Antioxid. Redox Signal. 6, 41 (2004).
A. K. Rundlof, M. Janard, A. Miranda-Vizuete, and E. S. Arnér, Free Radic. Biol. Med. 36, 641 (2004).
L. Li, M. A. Fath, P. M. Scarbrough, et al., Redox Biol. 4, 127 (2015).
J. L. Mohler, T. L. Morris, O. H. Ford, et al., Prostate 51, 247 (2002).
C. Méplan, S. Rohrmann, A. Steinbrecher, et al., PloS ONE 7, e48709 (2012).
J. K. Christman, Oncogene 21, 5483 (2002).
A. Roveri, A. Casasco, M. Maiorino, et al., J. Biol. Chem. 267, 6142 (1992).
R. Brigelius-Flohe, Free Radic. Biol. Med. 27, 951 (1999).
R. F. Burk and K. E. Hill, Bioassays 21, 231 (1999).
R. F. Burk, K. E. Hill, R. Read, and T. Bellew, Am._J. Physiol. 261, 26 (1991).
G. E. Olson, V. P. Winfrey, S. K. Nagdas, et al., Biol. Reprod. 73, 201 (2005).
M. Koga, H. Tanaka, K. Yomogida, et al., Biol. Reprod. 58, 261 (1998).
E. C. Wallace and H. L. Calvin, Gamete Res. 4, 389 (1983).
R. F. Burk, K. E. Hill, M. E. Boeglin, et al., Histochem. Cell Biol. 108, 11 (1997).
O. Gonzalez-Moreno, N. Boque, M. Redrado, et al., Prostate 71, 824 (2011).
G. E Olson, V. P. Winfrey, S. K. Nagdas, et al., J. Biol. Chem. 282, 12290 (2007).
S. C. Tsai, C. C. Lu, C. S. Lin, and P. S. Wang, J. Cell Biochem. 90, 1276 (2003).
K. Nishimura, K. Matsumiya, A. Tsujimura, et al., Arch. Androl. 47, 67 (2001).
Y. Gao, H. C. Feng, K. Walder, et al., FEBS Lett. 563, 185 (2004).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © E.G. Varlamova, 2016, published in Biofizika, 2016, Vol. 61, No. 4, pp. 686–691.
Rights and permissions
About this article
Cite this article
Varlamova, E.G. The role of selenium and selenocysteine-containing proteins in the mammalian male reproductive system. BIOPHYSICS 61, 580–584 (2016). https://doi.org/10.1134/S0006350916040266
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0006350916040266