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Impaired cortical oxygenation is related to mood disturbance resulting from three nights of sleep restriction

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Abstract

Chronic sleep restriction adversely effects cognitive performance and mood, resulting in accidents and economic loss. We examined the effects of three nights of sleep restriction on cortical oxygenation, cognitive performance and mood. We studied 14 young adults. All subjects spent ≥8 h/night in bed prior to the study day (sufficient sleep), followed by <4 h/night in bed for 3 days (insufficient sleep). Oxyhemoglobin (oxyHb) levels were measured with near-infrared spectroscopy during a word fluency task, and subjects underwent a continuous performance test-identical pairs version (CPT-IP) and filled out the Profile of Mood States (POMS) questionnaire. Peak oxyHb levels after the first and third insufficient sleep nights were significantly lower than that after the sufficient sleep night. Sustained reaction time after the first and third insufficient sleep nights was significantly shorter than that after the sufficient sleep night. Correct response on the CPT-IP after the first and third insufficient sleep nights was significantly less than after the sufficient sleep night. POMS vigor scores after the first and third insufficient sleep nights were both significantly lower than that after the sufficient sleep night. Fatigue and total mood disturbance scores of POMS were significantly higher after the third insufficient sleep night than those after the sufficient sleep night. Three nights of sleep restriction reduced the cortical oxygenation response, and might impair cognitive performance and promote mood disturbance.

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Authors and Affiliations

  1. Department of Biomedical Sciences, Chubu University, Japan

    Seiko Miyata & Akiko Noda (Professor)

  2. Department of Biomedical Sciences, Akiko Noda, Chubu University Graduate School of Life and Health Sciences, 1200 Matsumoto-cho Kasugai-shi, Aichi, 487-8501, Japan

    Akiko Noda (Professor)

  3. Department of Psychiatry, Nagoya University Graduate School of Medicine, Japan

    Kunihiro Iwamoto, Naoko Kawano, Masahiro Banno, Yoshiyuki Tsuruta & Norio Ozaki

  4. Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Graduate School of Pharmacy, Nagoya, Japan

    Yukihiro Noda

Authors
  1. Seiko Miyata
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  2. Akiko Noda
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  3. Kunihiro Iwamoto
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  4. Naoko Kawano
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  5. Masahiro Banno
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  6. Yoshiyuki Tsuruta
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  7. Yukihiro Noda
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  8. Norio Ozaki
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Corresponding author

Correspondence to Akiko Noda.

Additional information

This work was carried out at Chubu University, 1200 Matsumoto-cho, Kasugai-shi, 487–8501, Japan

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Miyata, S., Noda, A., Iwamoto, K. et al. Impaired cortical oxygenation is related to mood disturbance resulting from three nights of sleep restriction. Sleep Biol. Rhythms 13, 387–394 (2015). https://doi.org/10.1111/sbr.12130

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  • DOI: https://doi.org/10.1111/sbr.12130

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