Abstract
Early growth restriction followed by nutritional intakes that permit accelerated growth may result in adiposity and metabolic disease in later life. This study compared growth, body composition and nutritional intake between term age and 6 months post-term in 83 appropriate-for-gestational-age preterm infants with growth restriction at term age (AGA GR+), 15 AGA without growth restriction at term age (AGA GR−) and 33 small-for-gestational-age (SGA) preterm infants. AGA GR+ and SGA preterm infants had higher protein intake, higher energy intake and higher gain in weight SDS between term age and 6 months post-term, with similar lean mass (LM) and lower fat mass (FM) at 6 months post-term compared with AGA GR− preterm infants. In conclusion, despite higher energy and protein intake compared with AGA GR− preterm infants during the first 6 months post-term, AGA GR+ and SGA preterm infants restore their LM without excessive FM.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Finken M, Dekker F, de Zegher F, Wit J . Long-term height gain of prematurely born children with neonatal growth restraint: parallellism with the growth pattern of short children born small for gestational age. Pediatrics 2006; 118: 640–643.
Giannì M, Roggero P, Taroni F, Liotto N, Piemontese P, Mosca F . Adiposity in small for gestational age preterm infants assessed at term equivalent age. Arc Dis Child Fetal Neonatal Ed 2009; 94: F368–F372.
Euser A, Finken M, Keijzer-Veen M, Hille E, Wit J, Dekker F . Associations between prenatal and infancy weight gain and BMI, fat mass, and fat distribution in young adulthood: a prospective cohort study in males and females born very preterm. Am J Clin Nutr 2005; 81: 480–487.
Griffin I, Cooke R . Development of whole body adiposity in preterm infants. Early Hum Dev 2012; 88 (Suppl 1): S19–S24.
Amesz E, Schaafsma A, Cranendonk A, Lafeber H . Optimal growth and lower fat mass in preterm infants fed a protein-enriched postdischarge formula. J Pediatr Gastroenterol Nutr 2010; 50: 200–207.
Niklasson A, Albertsson-Wikland K . Continous growth reference from 24th weeks of gestation to 24 months by gender. BMC Pediatr 2008; 8: 8.
Fredriks A, van Buuren S, Burgmeijer R, Meulmeester J, Beuker R, Brugman E et al. Continuing positive secular growth change in the Netherlands 1955-1997. Pediatr Res 2000; 47: 316–323.
Roggero P, Gianni M, Liotto N, Taroni F, Orsi A, Amato O et al. Rapid recovery of fat mass in small for gestational age preterm infants after term. PLoS One 2011; 6: e14489.
van Goudoever J, Sulkers E, Lafeber H, Sauer P . Short-term growth and substrate use in very-low-birth-weight infants fed formulas with different energy contents. Am J Clin Nutr 2000; 71: 816–821.
Aggett P, Agostoni C, Axelsson I, DeCurtis M, Goulet O . Feeding preterm infants after hospital discharge. J Pediatr Gastroenterol Nutr 2006; 42: 596–603.
Acknowledgements
This work was supported by an unrestricted research grant of FrieslandCampina, Leeuwarden, The Netherlands.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Rights and permissions
About this article
Cite this article
van de Lagemaat, M., Rotteveel, J., Lafeber, H. et al. Lean mass and fat mass accretion between term age and 6 months post-term in growth-restricted preterm infants. Eur J Clin Nutr 68, 1261–1263 (2014). https://doi.org/10.1038/ejcn.2014.182
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/ejcn.2014.182
- Springer Nature Limited
This article is cited by
-
Body composition in late preterm infants according to percentile at birth
Pediatric Research (2016)