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Effect of Ambulatory 24-Hour Esophageal pH Monitoring on Reflux-Provoking Activities

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Abstract

Ambulatory 24-hr esophageal pH monitoring isconsidered the gold standard for diagnosinggastroesophageal reflux disease (GERD). The currentapproach is to encourage patients to pursue theireveryday activity in order to obtain near-physiologicalrecordings. However, the effect of the test itself onreflux-provoking activities has never been evaluated.Thus, the aim of our study was to assess daily foodconsumption, habits, symptoms, sleep, and perceivedexperience of patients undergoing pH testing as comparedto an off test (normal) day. Patients reported type andtime spent in each activity pursued, food ingested and length of each meal, habits, frequency andseverity of GERD and other related symptoms, sleepdisturbances, side effects, and overall perceivedexperience during pH testing and four weeks later,during a normal day. Fifty-four patients enrolled. pHtesting significantly reduced time spent being active,number of meals and cups of coffee consumed, andfrequency of GERD symptoms. Almost half of the patients reported having dysphagia during the test. Mostpatients experienced side effects and stated that thetest bothered them most of the time. In conclusion, pHtesting has a significant effect on decreasing reflux-provoking activities — patientstend to assume a more sedentary lifestyle. This mayinfluence the reliability of the test as a physiologicmeasure of acid reflux.

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REFERENCES

  1. Euler AR, Byrne WJ: Twenty four hour esophageal intraluminal pH probe testing: a comparative analysis. Gastroenterology 80:957-961, 1981

    Google Scholar 

  2. Richter JE, Castell DO: Gastroe sophageal reflux: pathogenesis, diagnosis and therapy. Ann Intern Med 97:93-103, 1982

    Google Scholar 

  3. Behar J, Biancani P, Sheahan DG: Evaluation of esophageal tests in the diagnosis of reflux esophagitis. Gastroenterology 71:9-15, 1976

    Google Scholar 

  4. Stanciu C, Hoare RC, Bennett JR: Correlation between manometric and pH tests for gastro-oesophageal reflux. Gut 18:536-540, 1977

    Google Scholar 

  5. Rosen SN, Pope CE: Extended esophageal pH monitoring. J Clin Gastroenterol 11:260-270, 1989

    Google Scholar 

  6. Jamieson JR, Sten HJ, DeMeester TR, Bonavian L, Schwizer W, Hinder RA, Albertucci M: Ambulatory 24-hour esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity and reproducibility. Am J Gastroenterol 87:1102-1111, 1992

    Google Scholar 

  7. Kahrilas PJ, Quigley EMM: American Gastrointestinal Association medical position statement: Guidelines on the use of esophageal pH recording. Gastroenterology 110:1981-1996, 1996

    Google Scholar 

  8. Mattox HE, Richter JE: Prolonged ambulatory 24-hour esophageal pH monitoring in the evaluation of gastroesophageal reflux disease. Am J Med 89:345-356, 1990

    Google Scholar 

  9. Schlesinger PK, Schmid DB, Layden TJ: Limitations of ambulatory 24-hour intraesophageal pH monitoring in the hospital setting. Gastroenterology 89:797-804, 1985

    Google Scholar 

  10. DeCaestecker JS, Blackwell JN, Pryde A, Heading RC: Daytime gastro-oesophageal reflux is important in oesophagitis. Gut 28:519-526, 1987

    Google Scholar 

  11. Fass R, Sampliner RE, Mackel C, McGee D, Rappaport W: Age-and gender-related differences in 24-hour esophageal pH monitoring of normal subjects. Dig Dis Sci 38:1926-1928, 1993

    Google Scholar 

  12. Wiener GJ, Morgan TM, Copper JB, Wu WC, Castell DO, Sinclair JW, Richter JE: Ambulatory 24-hour esophageal pH monitoring. Reproducibility and variability of pH parameters. Dig Dis Sci 33:1127-1133, 1988

    Google Scholar 

  13. Locke GR, Talley NJ, Zinsmeister AR: A new questionnaire for gastro esophageal reflux disease. Mayo Clinic Proc 69:539-547, 1994

    Google Scholar 

  14. Fass R, Fullerton S, Deihl DL, Mayer EA: Sleep disturbances (SD) in patients with functional bowel disorders (FBD). Gastroenterology 108:A596, 1995

    Google Scholar 

  15. Grande L, Culell P, Ros E, Lacima G, Pujol A, Garcia-Valdecasas JC, Fuster J, Visa J, Pera C: Comparison of stationary vs ambulatory 24-hour pH monitoring systems in diagnosis of gastroesophageal reflux disease. Dig Dis Sci 38:213-219, 1993

    Google Scholar 

  16. Fass R, Fennerty MB, Ofman JJ, Gralnek IM, Johnson C, Camargo E, Sampliner RE: The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain. Gastroenterology 115:42-49, 1998

    Google Scholar 

  17. Schenk BE, Kuipers EJ, Klinkenberg-Knol EC, Festen HPM, Jansen EH, Tyunman HARE, Schrijver M, Dieleman LA, Meuwissen SGM: Omeprazole as a diagnostic tool in gastroesophageal reflux disease. Am J Gastroenterol 92:1997-2000, 1997

    Google Scholar 

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Fass, R., Hell, R., Sampliner, R.E. et al. Effect of Ambulatory 24-Hour Esophageal pH Monitoring on Reflux-Provoking Activities. Dig Dis Sci 44, 2263–2269 (1999). https://doi.org/10.1023/A:1026608804938

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  • DOI: https://doi.org/10.1023/A:1026608804938

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